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pro vyhledávání: '"Shogo Koshida"'
Autor:
Shogo Koshida, Yohei Hirai
Publikováno v:
Biochemical and Biophysical Research Communications. 234:522-525
A mesenchymal protein, epimorphin, is known to bind directly to the cell surface through its central portion and to act as a signaling molecule for epithelial morphogenesis. Utilizing several recombinant polypeptides and synthetic peptides, we identi
Autor:
Derek C. Radisky, Shogo Koshida, Hokari Tsuda, Kyoko Takebe, Yumiko Oka, Katsuyuki C O Osaka Works Kogo, Keiko Tochigui, Yohei Hirai
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 17(14)
Epimorphin is a mesenchymal morphogen that has been shown to mediate epithelial-mesenchymal signaling interactions in various organs. We now show that epimorphin functions in hair follicle morphogenesis; using a novel ex vivo organ culture assay, we
Publikováno v:
The Journal of Cell Biology
Hepatocyte growth factor (HGF) and EGF have been reported to promote branching morphogenesis of mammary epithelial cells. We now show that it is epimorphin that is primarily responsible for this phenomenon. In vivo, epimorphin was detected in the str