Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shogo Inari"'
Autor:
Yuichiro Mita, Kaho Nakayama, Shogo Inari, Yukina Nishito, Yuya Yoshioka, Naoko Sakai, Kanade Sotani, Takahiro Nagamura, Yuki Kuzuhara, Kumi Inagaki, Miki Iwasaki, Hirofumi Misu, Masaya Ikegawa, Toshinari Takamura, Noriko Noguchi, Yoshiro Saito
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Selenoprotein P is secreted by the liver and when present in excess it promotes development of type 2 diabetes. Here the authors develop neutralizing antibodies to target human and mouse selenoprotein P, and show that they improve insulin secretion a
Externí odkaz:
https://doaj.org/article/9072caa59698443ba30fe40fdc34e5b3
Autor:
Yukina Nishito, Takahiro Nagamura, Toshinari Takamura, Yuki Kuzuhara, Naoko Sakai, Miki Iwasaki, Yuya Yoshioka, Hirofumi Misu, Noriko Noguchi, Kanade Sotani, Shogo Inari, Yoshiro Saito, Kumi Inagaki, Kaho Nakayama, Yuichiro Mita, Masaya Ikegawa
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Nature Communications
Nature Communications
Selenoprotein P (SeP) functions as a selenium (Se)-supply protein. SeP is identified as a hepatokine, promoting insulin resistance in type 2 diabetes. Thus, the suppression of Se-supply activity of SeP might improve glucose metabolism. Here, we devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::226b6b78d59c99b89d889456c152426a
http://link.springer.com/article/10.1038/s41467-017-01863-z
http://link.springer.com/article/10.1038/s41467-017-01863-z
Autor:
Takahiro Nagamura, Shogo Inari, Toshinari Takamura, Yoshiro Saito, Hirofumi Misu, Noriko Noguchi, Yuichiro Mita
Publikováno v:
Free Radical Biology and Medicine. 120:S78
Selenoprotein P (SeP; encoded by SELENOP) is a selenium (Se)-rich plasma protein and is synthesized mainly by the liver. SeP functions as a Se-supply protein to maintain antioxidative selenoprotein levels in peripheral tissue. Thus, SeP plays an esse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::908a1c1c9e69bfa92e6317637a8b7da7
https://doi.org/10.1016/j.freeradbiomed.2018.04.259
https://doi.org/10.1016/j.freeradbiomed.2018.04.259
Publikováno v:
Free Radical Biology and Medicine. 100:S174-S175
Selenoprotein P (SeP) is a liver-derived selenium (Se)-supply protein to maintain Se levels in peripheral tissues. The safety window of Se is narrow, even below the levels required for intoxication, supra-nutritional intake of Se has been reported to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c1fe6295f986a6ef31b43b03bb15ec6
https://doi.org/10.1016/j.freeradbiomed.2016.10.460
https://doi.org/10.1016/j.freeradbiomed.2016.10.460
Publikováno v:
Free Radical Biology and Medicine. 112:156
Selenoprotein P (SeP) is synthesized mainly by the liver and functions as a selenium (Se)-supply protein to maintain Se levels in peripheral tissue. SeP is identified as a hepatokine, promoting insulin resistance in type 2 diabetes. Recently, we foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13876721d3a6ed46f003a4b15b7b705c
https://doi.org/10.1016/j.freeradbiomed.2017.10.239
https://doi.org/10.1016/j.freeradbiomed.2017.10.239