Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Shoemark DK"'
Autor:
Celis, S, Hobor, F, James, T, Bartlett, GJ, Ibarra, AA, Shoemark, DK, Hegedüs, Z, Hetherington, K, Woolfson, DN, Sessions, RB, Edwards, TA, Andrews, DM, Nelson, A, Wilson, AJ
Protein–protein interactions (PPIs) are central to biological mechanisms, and can serve as compelling targets for drug discovery. Yet, the discovery of small molecule inhibitors of PPIs remains challenging given the large and typically shallow topo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::11debccf988e715c53d9305e43a6f9c2
https://eprints.whiterose.ac.uk/171361/2/d1sc00023c.pdf
https://eprints.whiterose.ac.uk/171361/2/d1sc00023c.pdf
Autor:
Smith, SA, Sessions, RB, Shoemark, DK, Williams, C, Ebrahimighaei, R, McNeill, MC, Crump, MP, McKay, TR, Harris, G, Newby, AC, Bond, M
Publikováno v:
Smith, S A, Sessions, R B, Shoemark, D K, Williams, C, Ebrahimighaei, R, McNeill, M C, Crump, M P, McKay, T R, Harris, G, Newby, A C & Bond, M 2019, ' Antiproliferative and Antimigratory Effects of a Novel YAP-TEAD Interaction Inhibitor Identified Using in Silico Molecular Docking ', Journal of Medicinal Chemistry, vol. 62, no. 3, pp. 1291-1305 . https://doi.org/10.1021/acs.jmedchem.8b01402
© Copyright 2019 American Chemical Society. The Hippo pathway is an important regulator of cell growth, proliferation, and migration. TEAD transcription factors, which lie at the core of the Hippo pathway, are essential for regulation of organ growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bd2c1769f941be67765bcabacea0e117
https://research-information.bris.ac.uk/ws/files/185252962/acs.jmedchem.8b01402.pdf
https://research-information.bris.ac.uk/ws/files/185252962/acs.jmedchem.8b01402.pdf
Publikováno v:
The FASEB journal 32 (2018): 2223–2234.
info:cnr-pdr/source/autori:Shoemark DK (1), Sessions RB (1), Brancaccio A (1,2), Bigotti MG (1)./titolo:Intraring allostery controls the function and assembly of a hetero-oligomeric class II chaperonin./doi:/rivista:The FASEB journal/anno:2018/pagina_da:2223/pagina_a:2234/intervallo_pagine:2223–2234/volume:32
info:cnr-pdr/source/autori:Shoemark DK (1), Sessions RB (1), Brancaccio A (1,2), Bigotti MG (1)./titolo:Intraring allostery controls the function and assembly of a hetero-oligomeric class II chaperonin./doi:/rivista:The FASEB journal/anno:2018/pagina_da:2223/pagina_a:2234/intervallo_pagine:2223–2234/volume:32
Class II chaperonins are essential multisubunit complexes that aid the folding of nonnative proteins in the cytosol of archaea and eukarya. They use energy derived from ATP to drive a series of structural rearrangements that enable polypeptides to fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=cnr_________::0208c64adff425ea79158736cf5b480b
http://www.cnr.it/prodotto/i/388052
http://www.cnr.it/prodotto/i/388052
Akademický článek
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Akademický článek
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Autor:
Langlands HD; School of Biochemistry, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK., Shoemark DK; School of Biochemistry, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK., Toye AM; School of Biochemistry, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Publikováno v:
Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2024 Sep 02; Vol. 13 (9). Date of Electronic Publication: 2024 Sep 02.
Autor:
Wyatt RC; Diabetes and Metabolism Unit, Translational Health Sciences, University of Bristol, Bristol, U.K., Grace SL; Diabetes and Metabolism Unit, Translational Health Sciences, University of Bristol, Bristol, U.K., Brigatti C; San Raffaele Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy., Marzinotto I; San Raffaele Diabetes Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy., Gillard BT; Diabetes and Metabolism Unit, Translational Health Sciences, University of Bristol, Bristol, U.K., Shoemark DK; School of Biochemistry, University of Bristol, Bristol, U.K., Chandler K; Diabetes and Metabolism Unit, Translational Health Sciences, University of Bristol, Bristol, U.K., Achenbach P; Institute of Diabetes Research, Helmholtz Munich, German Center for Environmental Health, Munich, Germany.; Technical University of Munich, School of Medicine, Klinikum rechts der Isar, Forschergruppe Diabetes, Munich, Germany., Piemonti L; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Long AE; Diabetes and Metabolism Unit, Translational Health Sciences, University of Bristol, Bristol, U.K., Gillespie KM; Diabetes and Metabolism Unit, Translational Health Sciences, University of Bristol, Bristol, U.K., Lampasona V; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Williams AJK; Diabetes and Metabolism Unit, Translational Health Sciences, University of Bristol, Bristol, U.K.
Publikováno v:
Diabetes [Diabetes] 2024 Apr 01; Vol. 73 (4), pp. 565-571.
Autor:
Oliveira ASF; School of Chemistry, Centre for Computational Chemistry, University of Bristol, Bristol BS8 1TS, UK.; School of Chemistry, University of Bristol, Bristol BS8 1TS, UK.; School of Biochemistry, University of Bristol, Bristol BS8 1TD, UK., Shoemark DK; School of Biochemistry, University of Bristol, Bristol BS8 1TD, UK., Davidson AD; School of Cellular and Molecular Medicine, University of Bristol, University Walk, Bristol BS8 1TD, UK., Berger I; School of Chemistry, University of Bristol, Bristol BS8 1TS, UK.; School of Biochemistry, University of Bristol, Bristol BS8 1TD, UK.; School of Chemistry, Max Planck Bristol Centre for Minimal Biology, Bristol BS8 1TS, UK., Schaffitzel C; School of Biochemistry, University of Bristol, Bristol BS8 1TD, UK., Mulholland AJ; School of Chemistry, Centre for Computational Chemistry, University of Bristol, Bristol BS8 1TS, UK.
Publikováno v:
Journal of molecular cell biology [J Mol Cell Biol] 2023 Aug 03; Vol. 15 (3).
Autor:
Jiménez-Moreno N; Cell Biology Laboratories, School of Biochemistry, University of Bristol , Bristol, UK., Kollareddy M; Cell Biology Laboratories, School of Biochemistry, University of Bristol , Bristol, UK., Stathakos P; Cell Biology Laboratories, School of Biochemistry, University of Bristol , Bristol, UK., Moss JJ; Cell Biology Laboratories, School of Biochemistry, University of Bristol , Bristol, UK., Antón Z; Cell Biology Laboratories, School of Biochemistry, University of Bristol , Bristol, UK., Shoemark DK; School of Biochemistry, University of Bristol , Bristol, UK., Sessions RB; School of Biochemistry, University of Bristol , Bristol, UK., Witzgall R; Institute for Molecular and Cellular Anatomy, University of Regensburg , Regensburg, Germany., Caldwell M; Trinity College Institute for Neuroscience, Trinity College Dublin , Dublin, Ireland., Lane JD; Cell Biology Laboratories, School of Biochemistry, University of Bristol , Bristol, UK.
Publikováno v:
The Journal of cell biology [J Cell Biol] 2023 May 01; Vol. 222 (5). Date of Electronic Publication: 2023 Apr 04.