Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Shoeb I. Khan"'
Autor:
Jenna Wilson, Debra G Wheeler, Laura J. Sommerville, David Dornbos, Kendyl Carlisle, Nicholas Venetos, Richard C. Becker, Shahid M Nimjee, Juliana M. Layzer, George A. Pitoc, Nicholas Musgrave, Allyson Huttinger, Spencer Talentino, Shoeb I. Khan, Holly Moody, Bruce A. Sullenger, Jay L. Zweier, Camille Bratton, Rachel E. Rempel, Matthew Joseph, Maureane Hoffman, Cheyenne Jones
Publikováno v:
Mol Ther
Endothelial surface and circulating glycoprotein von Willebrand factor (vWF) regulates platelet adhesion and is associated with thrombotic diseases, including ischemic stroke, myocardial infarction, and peripheral vascular disease. Thrombosis, as man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a4909ecd632d79e90e5038b60fb450
https://doi.org/10.1016/j.ymthe.2019.03.016
https://doi.org/10.1016/j.ymthe.2019.03.016
Publikováno v:
Inorganic Chemistry. 38:3922-3925
A facile procedure for the incorporation of Ru(bpy)32+ in an oligonucleotide is reported. A Ru(bpy)32+ phosphoramidite is synthesized, and then attached to the 5‘-terminus of DNA using a standard protocol on an automated DNA solid-phase synthesizer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fd4386a05941dfd24d86f43dc7b52d0
https://doi.org/10.1021/ic990177y
https://doi.org/10.1021/ic990177y
Publikováno v:
Inorganic Chemistry. 38:2411-2415
The synthesis and photophysical properties of a novel ruthenium-modified nucleoside are reported. The key synthetic step to 5-[Ru(bpy)2(4-m-4‘-pa-bpy)]2+-2‘-deoxyuridine involves the Pd(0)-catalyzed cross-coupling of a propargylamine-derivatized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a971a8ba576ed41d39687b2b0338e3c0
https://doi.org/10.1021/ic990067r
https://doi.org/10.1021/ic990067r
Autor:
Shoeb I. Khan, Mark W. Grinstaff
Publikováno v:
Tetrahedron Letters. 39:8031-8034
The solid-phase synthesis of a nucleoside hydroxamic acid is accomplished by the Pd(0) cross-coupling of 5-iodouridine and an O-linked hydroxylamine alkyne bound to 2-chlorotrityl chloride polystyrene resin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e33bf2dd1f7ffc16c1231a8065ab199
https://doi.org/10.1016/s0040-4039(98)01794-8
https://doi.org/10.1016/s0040-4039(98)01794-8
Publikováno v:
Nucleosides and Nucleotides. 13:1049-1058
Synthesis and antifungal activity of 3′-deoxyribo-nucleosides containing naturally occurring pyrimidine and purine bases are reported.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c72b7186feec30482dd7bc44ac56cf75
https://doi.org/10.1080/15257779408011878
https://doi.org/10.1080/15257779408011878
Autor:
Mark W. Grinstaff, Shoeb I. Khan
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::245de6f0185f033938ba3a16c0082e92
https://doi.org/10.1002/chin.199927239
https://doi.org/10.1002/chin.199927239
Publikováno v:
The Journal of Physical Chemistry B. 104:7574-7576
Kinetics of a photoinduced electron-transfer reaction between phenothiazine (PTZ) and Ru(bpy)2(4-m-4‘-pa-bpy)2+ [bpy = 2,2‘-bipyridine and 4-m-4‘-pa-bpy = 4-methyl-4‘-carbonylpropargylamine] covalently bound to a DNA duplex is investigated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95fe7a1d9d35b901f0c9b1843b1f8703
https://doi.org/10.1021/jp001539m
https://doi.org/10.1021/jp001539m
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 24(5-7)
The 5-ethynyl-2'-deoxyuridine nucleoside and the 5'-boranomonophosphate nucleotide were synthesized as analogs of 5-fluoro-2'-deoxyuridine monophosphate (5-FdUMP), a widely used mechanism-based inhibitor of thymidylate synthase. Synthesis was carried
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131149259f648998ddc706674f385982
https://pubmed.ncbi.nlm.nih.gov/16248089
https://pubmed.ncbi.nlm.nih.gov/16248089
Autor:
Thomas L. Ortel, Richard C. Becker, Deborah A. Lewis, Shahid M Nimjee, Shoeb I. Khan, George A. Pitoc, Bruce A. Sullenger
Publikováno v:
Blood. 124:4279-4279
Introduction: Many cardiovascular procedures including percutaneous coronary intervention, coronary bypass surgery, and peripheral vascular surgery require antithrombotic therapy during the procedure. Heparin is frequently used, due to low cost, ease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdd97e026dcc7c4fba6205ead77d670a
https://doi.org/10.1182/blood.v124.21.4279.4279
https://doi.org/10.1182/blood.v124.21.4279.4279
Publikováno v:
Inorganic chemistry. 38(26)
A facile procedure for incorporating a Ru(diimine)(3)(2+) complex at the nucleobase in an oligonucleotide is reported that combines the advantages of Pd(0) cross-coupling and solid-phase DNA chemistries. These ruthenium-modified oligonucleotides form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::320367ce43dc1152666fc21f9eadf7ff
https://pubmed.ncbi.nlm.nih.gov/11671306
https://pubmed.ncbi.nlm.nih.gov/11671306