Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Shobhona Sharma"'
Publikováno v:
Life, Vol 13, Iss 8, p 1684 (2023)
Background: The major focus of metabolomics research has been confined to the readily available biofluids—urine and blood serum. However, red blood cells (RBCs) are also readily available, and may be a source of a wealth of information on vertebrat
Externí odkaz:
https://doaj.org/article/df8ba92537a44030b7c75bd50d97a829
Publikováno v:
Metabolites, Vol 10, Iss 7, p 277 (2020)
Investigation of glucose utilization during an infection is central to the study of energy metabolism. The heavy utilization of glucose by the malaria parasite, and the consequences of this process, have been investigated extensively. However, host g
Externí odkaz:
https://doaj.org/article/26b8a531ae5142edb2c0241064704f85
Publikováno v:
PeerJ, Vol 5, p e3128 (2017)
The secretory pathway in Plasmodium falciparum has evolved to transport proteins to the host cell membrane and to an endosymbiotic organelle, the apicoplast. The latter can occur via the ER or the ER-Golgi route. Here, we study these three routes usi
Externí odkaz:
https://doaj.org/article/9aeb5d9b9b4842b39b00812141ccdc9b
Autor:
Esther Dalko, Nicolas Tchitchek, Laurent Pays, Fabien Herbert, Pierre-André Cazenave, Balachandran Ravindran, Shobhona Sharma, Serge Nataf, Bidyut Das, Sylviane Pied
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158420 (2016)
Cerebral malaria (CM) caused by Plasmodium falciparum parasites often leads to the death of infected patients or to persisting neurological sequelae despite anti-parasitic treatments. Erythropoietin (EPO) was recently suggested as a potential adjunct
Externí odkaz:
https://doaj.org/article/c94ce17dad3d495a8372261e5663c99f
Autor:
Shobhona Sharma, Sulabha Pathak
Publikováno v:
Journal of Vector Borne Diseases, Vol 45, Iss 1, Pp 1-20 (2008)
The observation that inactivated Plasmodium sporozoites could protect against malaria is about a hundred years old. However, systematic demonstration of protection using irradiated sporozoites occurred in the nineteen-sixties, providing the impetus f
Externí odkaz:
https://doaj.org/article/21443d46debd46c495443e1603b2b918
Study of P. falciparum-infected erythrocytes and induced anisotropies under optical and fluid forces
Publikováno v:
Journal of Vector Borne Diseases, Vol 44, Iss 1, Pp 23-32 (2007)
Background & objectives: The effect of P. falciparum on erythrocytes has been studied for a longtime at the population level but actual studies at the single cell level remain largely unexplored. Theaim of this study was to address the host-parasite
Externí odkaz:
https://doaj.org/article/f8b0fe83203c46908a2cb62a288c75a4
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73113 (2013)
A significant fraction of global population is under the threat of malaria. Majority of annual death is due to the more complicated form of the infection i.e. the cerebral form, also known as Cerebral Malaria (CM). Host parasite interaction is known
Externí odkaz:
https://doaj.org/article/8cad0235aa34424f9212707228ee993c
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66954 (2013)
Malaria, a mosquito-borne disease caused by Plasmodium spp. is considered to be a global threat, specifically for the developing countries. In human subjects considerable information exists regarding post-malarial physiology. However, most murine mal
Externí odkaz:
https://doaj.org/article/0613061023ae4b88a5a78fd3c6c5976e
Publikováno v:
PLoS Pathogens, Vol 8, Iss 8 (2012)
Externí odkaz:
https://doaj.org/article/eb8c1ea479bc49049dc18ebdc528539d
Autor:
Sulabha Pathak, Mayuri Rege, Nithya J Gogtay, Umesh Aigal, Surya Kant Sharma, Neena Valecha, Gyan Bhanot, Nilima A Kshirsagar, Shobhona Sharma
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35592 (2012)
Background and objectivesExperimental models show a male bias in murine malaria; however, extant literature on biases in human clinical malaria is inconclusive. Studies in hyperendemic areas document an absence of sexual dimorphism in clinical malari
Externí odkaz:
https://doaj.org/article/e7bb0adbe36c4deeb4f70d4f187aecb1