Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shobha Gokul"'
Autor:
Brian C. Haynes, Richard A. Blidner, Robyn D. Cardwell, Robert Zeigler, Shobha Gokul, Julie R. Thibert, Liangjing Chen, Junya Fujimoto, Vassiliki A. Papadimitrakopoulou, Ignacio I. Wistuba, Gary J. Latham
Publikováno v:
Translational Oncology, Vol 12, Iss 6, Pp 836-845 (2019)
We developed and characterized a next-generation sequencing (NGS) technology for streamlined analysis of DNA and RNA using low-input, low-quality cancer specimens. A single-workflow, targeted NGS panel for non–small cell lung cancer (NSCLC) was des
Externí odkaz:
https://doaj.org/article/a8950f9ea35a4e3aab0cccfb16ee6416
Autor:
Gary J. Latham, Robert Zeigler, Robyn D. Cardwell, Brian C. Haynes, Vassiliki A. Papadimitrakopoulou, Ignacio I. Wistuba, Junya Fujimoto, Richard A. Blidner, Liangjing Chen, Shobha Gokul, Julie R. Thibert
Publikováno v:
Translational Oncology, Vol 12, Iss 6, Pp 836-845 (2019)
We developed and characterized a next-generation sequencing (NGS) technology for streamlined analysis of DNA and RNA using low-input, low-quality cancer specimens. A single-workflow, targeted NGS panel for non–small cell lung cancer (NSCLC) was des
Autor:
Richard A. Blidner, Gary J. Latham, Sarah Schmitt, Ziyan Y. Pessetto, Dan Su, Robyn D. Cardwell, Andrew K. Godwin, Stephen Hyter, Léon C van Kempen, Shobha Gokul, Maria Aguirre, Patrick Hurban, Brian C. Haynes
Publikováno v:
The Journal of Molecular Diagnostics : JMD
Lung cancer accounts for approximately 14% of all newly diagnosed cancers and is the leading cause of cancer-related deaths. Chimeric RNA resulting from gene fusions (RNA fusions) and other RNA splicing errors are driver events and clinically address
Autor:
Yasef Khan, Shobha Gokul, Gary J. Latham, Francisco Ramirez, Lawrence Manzano, Louis Leong, Chris Heger
Publikováno v:
Cancer Research. 80:6296-6296
Introduction: Integration of multiple classes of biomarkers, including proteins, DNA and RNA, offers insights into the complexities of spatial, temporal, and functional biology beyond those possible with any one class. The distinct properties and det
Autor:
Blake Printy, Yves Konigshofer, Farol L. Tomson, Jessica L. Larson, Gary J. Latham, Brian C. Haynes, Sarah N. Statt, Jeffrey Shelton, Liangjing Chen, Joseph K. Kaplan, Shobha Gokul, Lando Ringel
Publikováno v:
Cancer Research. 78:5574-5574
Introduction: Mutation analysis of circulating tumor DNA (ctDNA) in blood-based liquid biopsies provides a minimally invasive approach to detect and monitor disease. Existing next-generation sequencing (NGS) liquid biopsy techniques have laborious an
Autor:
T Halsey, Ziyan Y. Pessetto, Victor J. Weigman, Gary J. Latham, Dan Su, Andrew K. Godwin, Patrick Hurban, Richard A. Blidner, Shobha Gokul, Maria Aguirre, Brian C. Haynes, Stephen Hyter, Léon C van Kempen, Maria Curtis
Publikováno v:
Cancer Research. 77:1764-1764
Introduction: Reliable assessment of cancer-associated RNA markers in lung cancer produced by gene-fusions or exon skipping events by next-generation sequencing requires integrated reagents, protocols, and interpretive software that can harmonize pro
Autor:
Ignacio I. Wistuba, Robert Zeigler, Brian C. Haynes, Michael E. Dodge, Julie Krosting, Liangjing Chen, Vassiliki A. Papadimitrakopoulou, Shobha Gokul, Jason Plyler, Junya Fujimoto, Richard A. Blidner, Gary J. Latham
Publikováno v:
Cancer Research. 76:1389-1389
Introduction: The promise of precision medicine relies on the identification of DNA and RNA markers that can individualize patient management. Methods such as next-generation sequencing (NGS) can deduce DNA or RNA sequences, but both types of nucleic