Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Shoba Shetty"'
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 8, Pp 1700-1713 (2006)
Previous studies have suggested that HDL retroendocytosis may play a role in scavenger receptor class B type I (SR-BI)-dependent selective lipid uptake in a cell-specific manner. To investigate this possibility, we developed methods to quantitatively
Externí odkaz:
https://doaj.org/article/7f0a7f27710247058658187c69d6a275
Autor:
Suzette Girgis, Shun Xin Wang Lin, Kodandaram Pillarisetti, Arnob Banerjee, Tara Stephenson, Xuewen Ma, Shoba Shetty, Tong-Yuan Yang, Brandi W. Hilder, Qun Jiao, Brett Hanna, Homer C Adams, Yu-Nien Sun, Amarnath Sharma, Jennifer Smit, Jeffrey R. Infante, Jenna D. Goldberg, Yusri Elsayed
Publikováno v:
Targeted Oncology. 17:433-439
Teclistamab (JNJ-64007957), a B-cell maturation antigen × CD3 bispecific antibody, displayed potent T-cell-mediated cytotoxicity of multiple myeloma cells in preclinical studies.A first-in-human, Phase I, dose escalation study (MajesTEC-1) is evalua
Autor:
Shou-Ching Jaminet, Harold F. Dvorak, Anthony J. Coyle, Leigh Zawel, Anthony Barry, Shoba Shetty, Mauricio Leal, Anson K. Abraham, William B. Snyder, Robert Dunn, Xianjun Cao, Andreas Maderna, Christopher J. O'Donnell, Dan Li, Lioudmila Tchistiakova, Sadhana Jain, Kimberly Marquette, Xiang Zheng, Chi-Iou Lin, Edyta Tyminski, Kelly Knowlton, Alberto Visintin
Supplementary Figures S1-S6. Supplementary Figure S1. Liquid chromatography electrospray ionization tandem mass spectrometry analysis; Supplementary Figure S2. TM4SF1 expression in human breast and colon cancers; Supplementary Figure S3A. Clearance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d85d555fe06140285b3604e384e0d0
https://doi.org/10.1158/1535-7163.22505884.v1
https://doi.org/10.1158/1535-7163.22505884.v1
Autor:
Suzette Girgis, Shun Xin Wang Lin, Kodandaram Pillarisetti, Arnob Banerjee, Tara Stephenson, Xuewen Ma, Shoba Shetty, Tong-Yuan Yang, Brandi W. Hilder, Qun Jiao, Brett Hanna, Homer C. Adams, Yu-Nien Sun, Amarnath Sharma, Jennifer Smit, Jeffrey R. Infante, Jenna D. Goldberg, Yusri Elsayed
Publikováno v:
Targeted Oncology. 17:609-609
Autor:
Mark Mendonca, Ricardo Attar, Francois Gaudet, Yingzhe Li, Jocelin Joseph, Eileen Walsh, Suzanne Edavettal, Matt Husovsky, Mark Tornetta, Kodandaram Pillarisetti, Nate Majewski, Gerald Chu, Shoba Shetty, Yusri Elsayed, Alexander Babich, Dara Reeves, Leopoldo Luistro, Diana Chin, Kathryn Packman
T-cell–mediated approaches have shown promise in myeloma treatment. However, there are currently a limited number of specific myeloma antigens that can be targeted, and multiple myeloma (MM) remains an incurable disease. G-protein–coupled recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696d6f4bc66787d11b99970af2b12bc3
https://europepmc.org/articles/PMC7146017/
https://europepmc.org/articles/PMC7146017/
Autor:
Suzette Girgis, Brandi Hilder, Jennifer Smit, Brett Hanna, Yu-Nien Sun, Amarnath Sharma, Shoba Shetty, Homer Adams, Shun Xin Wang Lin, Jeffrey R. Infante, Jenna D. Goldberg, Arnob Banerjee, Tara Stephenson, Yusri Elsayed, Kodandaram Pillarisetti
Publikováno v:
Blood. 136:35-35
B cell maturation antigen (BCMA; CD269; TNFRSF17) is a surface receptor, expressed on benign and malignant plasma cells. The restricted expression of BCMA on B-cell lineage makes it an ideal target for multiple myeloma (MM) immunotherapy. BCMAxCD3 bi
Publikováno v:
The American Journal of Pathology. 178:2690-2699
In this study, we elucidated the mechanism by which adiponectin modulates hepatic stellate cell activation and fibrogenesis. Adiponectin-overexpressing transgenic mice receiving thioacetamide were resistant to fibrosis, compared with controls. In con
Autor:
Xiang Zheng, Anthony Barry, Shoba Shetty, William B. Snyder, Kelly M. Knowlton, Kimberly Ann Marquette, Edyta Tyminski, Anthony J. Coyle, Christopher J. O’Donnell, Harold F. Dvorak, Chi-Iou Lin, Lioudmila Tchistiakova, Sadhana Jain, Shou-Ching S. Jaminet, Leigh Zawel, Xianjun Cao, Mauricio Leal, Alberto Visintin, Anson K. Abraham, Dunn Robert Joseph, Dan Li, Andreas Maderna
Publikováno v:
Molecular cancer therapeutics. 14(8)
Antibody–drug conjugates (ADC) represent a promising therapeutic modality for managing cancer. Here, we report a novel humanized ADC that targets the tetraspanin-like protein TM4SF1. TM4SF1 is highly expressed on the plasma membranes of many human
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 26:2125-2131
Objective— The high-density lipoprotein (HDL) receptor scavenger receptor Class B type I (SR-BI) plays a key role in mediating the final step of reverse cholesterol transport. This study examined the possible regulation of hepatic SR-BI by phosphat
Autor:
Erik Eckhardt, Shoba Shetty, Lei Cai, Nancy R. Webb, Deneys R. van der Westhuyzen, Zhenze Zhao, Attila Szanto
Publikováno v:
Journal of Biological Chemistry. 281:4348-4353
The high density lipoprotein (HDL) receptor Scavenger Receptor BII (SR-BII) is encoded by an alternatively spliced mRNA from the SR-BI gene and is expressed in various tissues. SR-BII protein differs from SR-BI only in the carboxyl-terminal cytoplasm