Výsledky vyhledávání - "Shoba P Dsouza"

Evidence for presence of mismatch repair gene expression positive Lynch syndrome cases in India

Autor: Murali D. Bashyam, Ashavaid Tester, Mohana Vamsy, Satish Rao, Ravikanth Kongara, Shantveer G Uppin, Viswakalyan Kotapalli, Brijesh K. Yadav, Ratheesh Raman, Ajay K. Chaudhary, Devendra Desai, Shoba P Dsouza, Swarnalata Gowrishankar, Sujit Patnaik, Regulagadda A. Sastry

Publikováno v: Molecular Carcinogenesis. 54:1807-1814

Lynch syndrome (LS), the most common form of familial CRC predisposition that causes tumor onset at a young age, is characterized by the presence of microsatellite instability (MSI) in tumors due to germline inactivation of mismatch repair (MMR) syst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::caae6b3fc69cb93f76c8845cde169c62
https://doi.org/10.1002/mc.22244

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Genome scan study of prostate cancer in Arabs: identification of three genomic regions with multiple prostate cancer susceptibility loci in Tunisians

Autor: Danny M. Rabah, Hala Kfoury, Shahzad Jafri, Issam Al-Bozom, Dhanya Kizhakayil, Idil I. Aigha, Hanif Khalak, Jillian Rowe, Karim Farhat, Lotfi Chouchane, Sami Alsaid, Shoba P Dsouza, Jingxuan Shan, Khalid Al-Rumaihi

Publikováno v: Journal of Translational Medicine

Background Large databases focused on genetic susceptibility to prostate cancer have been accumulated from population studies of different ancestries, including Europeans and African-Americans. Arab populations, however, have been only rarely studied

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f3794258578e5ffd030f84d4c74f86
https://doi.org/10.1186/1479-5876-11-121

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TNRC9 downregulates BRCA1 expression and promotes breast cancer aggressiveness

Autor: Dhanya Kizhakayil, Stacia Furtado, Idil I. Aigha, Lotfi Chouchane, Eman K. Al-Azwani, Shahinaz Bedri, Ena Wang, Joel A. Malek, Jingxuan Shan, Issam Al-Bozom, Edith Mathiowitz, Shoba P Dsouza, Sasha Bakhru, Salah Gehani, Francesco M. Marincola, Konduru S Sastry, Maria Libera Ascierto

Publikováno v: Cancer research. 73(9)

Although the linkage between germline mutations of BRCA1 and hereditary breast/ovarian cancers is well established, recent evidence suggests that altered expression of wild-type BRCA1 might contribute to the sporadic forms of breast cancer. The breas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df22df028110800952ebfddc60dfac1
https://pubmed.ncbi.nlm.nih.gov/23447579

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Genome-Wide Association Studies (GWAS) breast cancer susceptibility loci in Arabs: susceptibility and prognostic implications in Tunisians

Autor: Idil I. Aigha, Hager Memmi, Lotfi Chouchane, Wijden Mahfoudh, Noureddine Bouaouina, Jingxuan Shan, Sonia Abdelhak, Sallouha Gabbouj, Elham Hassen, Rebecca Mathew, Ahlem Benhadjayed, Yassmine Remadi, Shoba P Dsouza

Publikováno v: Breast Cancer Research and Treatment
Breast Cancer Research and Treatment, Springer Verlag, 2012, 135 (3), pp.715-24. ⟨10.1007/s10549-012-2202-6⟩

Genome-wide Association Studies (GWAS) revealed novel genetic markers for breast cancer susceptibility. But little is known about the risk factors and molecular events associated with breast cancer in Arab Population. Therefore, we designed a broad s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffcde7c174fe2b743da2d13d0da814e0
https://hal-riip.archives-ouvertes.fr/pasteur-01375153

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Genome-wide association study of prostate cancer in Arab populations: Identification of three genomic regions with multiple consecutive prostate cancer susceptibility loci

Autor: Shoba P Dsouza, Jingxuan Shan, Dhanya Kizhakayil, Issam Al-Bozom, Khalid Al-Rumaihi, Karim Farhat, Danny Rabah, Idil I. Aigha, Lotfi Chouchane, Sami Alsaid

Publikováno v: Qatar Foundation Annual Research Forum Volume 2012 Issue 1.

Background: Prostate cancer is the most common malignancy in many industrialized countries and the second cause of cancer-related death in Europe and the United States. The incidence of the disease has been increasing in Arab populations. Large datab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::256ecdda223d364499b8334daaafc98c
https://doi.org/10.5339/qfarf.2012.bmp71

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TNRC9 (TOX3) downregulates BRCA1 expression and promotes breast cancer aggressiveness

Autor: Issam Al-Bozom, Joel A. Malek, Maria Libera Ascierto, Jingxuan Shan, Francesco M. Marincola, Konduru S Sastry, Shoba P Dsouza, Shahinaz Bedri, Salah Gehani, Idil I. Aigha, Sasha Bakhru, Lotfi Chouchane, Dhanya Kizhakayil, Stacia Furtado, Eman K. Al-Azwani, Ena Wang, Edith Mathiew

Publikováno v: Qatar Foundation Annual Research Forum Volume 2012 Issue 1.

Background: Although the linkage between germline mutations of BRCA1 and hereditary breast/ovarian cancers is well established, recent evidence suggests that altered expression of wild type BRCA1 might contribute to the sporadic forms of breast cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::860f858c4a46baf807d8625937d32b10
https://doi.org/10.5339/qfarf.2012.bmo5

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PCA3 molecular urine test: Development of an easy and cheap assay of a potential use in the diagnosis of prostate cancer

Autor: Jingxuan Shan, Idil I. Aigha, Lotfi Chouchane, Sami Alsaid, Khalid Al-Rumaihi, Shoba P Dsouza, Dhanya Kizhakayil

Publikováno v: Qatar Foundation Annual Research Forum Volume 2012 Issue 1.

Background: The use of the serum prostate-specific antigen (PSA) test for prostate cancer screening has resulted in a diagnostic dilemma: PSA is not prostate cancer specific and could be found in the normal prostate at equal or higher levels than is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::089795ba1139d866de5250aa7e3ed590
https://doi.org/10.5339/qfarf.2012.bmp80

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Prevalence of Metabolic Syndrome in Urban India

Autor: Seema P. Todur, Apurva Sawant, Ranjit Mankeshwar, Pradnya Dhairyawan, Swarup A V Shah, Tester F. Ashavaid, Rani Raghavan, Shoba P Dsouza, Aarti Subramanium, Himanshu Raje, Gargi Dhongde

Publikováno v: Cholesterol
Cholesterol, Vol 2011 (2011)

Background. Metabolic syndrome (MS) is characterised by a constellation of individual risk factors of cardiovascular disease. Materials and Methods. The current study was a population-based survey of cohort of subjects in the metropolitan city of Mum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684da95ae1a3a55c967583b11748cd5f
http://europepmc.org/articles/PMC3114375

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Abstract 1285: Identification of MMR gene exonic rearrangements in suspected Lynch syndrome tumors without loss of MMR expression

Autor: Ratheesh Raman, Murali D. Bashyam, Tester F. Ashavaid, Devendra Desai, Ajay K. Chaudhary, Sujit Patnaik, Ravikanth Kongara, Shantveer G Uppin, Mohana Vamsy, Shoba P Dsouza, Swarnalata Gowrishankar, Regulagadda A. Sastry, Viswakalyan Kotapalli, Brijesh K. Yadav

Publikováno v: Cancer Research. 74:1285-1285

Lynch syndrome (LS), also called Hereditary Non-Polyposis Colorectal Cancer, the most well studied form of familial CRC, is responsible for about 3% of all CRC cases. LS-associated CRC often exhibits one or more of the following features namely early

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11a13b26eb3e8818a809ac16de9c1579
https://doi.org/10.1158/1538-7445.am2014-1285

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