Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Shoba A. Navai"'
1
Pediatric liposarcoma: A case series and literature review
Autor: Sarah B. Whittle, Rajkumar Venkatramani, Shoba A. Navai, Yiressy Izaguirre Baday, M. John Hicks
Publikováno v: Pediatric bloodcancerREFERENCES. 68(12)
Liposarcoma is arare soft tissue sarcoma in children. While prognosis, clinical behavior, and response to therapy among the various histologic subtypes are well described in adults, data in children are limited. Here, we describe our experience treat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a06b5579cae159ef0ac8803f29c30c2
https://pubmed.ncbi.nlm.nih.gov/34520106
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3
Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma
Autor: Christopher DeRenzo, Stephen Gottschalk, John Hicks, Winfried S. Wels, Catherine Robertson, Tiara T. Byrd, Olga Dakhova, Ankita Shree, Farzana Pashankar, Nabil Ahmed, Khaled Sanber, Gianpietro Dotti, Claudia Gerken, Mina L. Xu, Meenakshi Hegde, Vita S. Salsman, Sujith K. Joseph, Helen E. Heslop, Bambi Grilley, Mamta Kalra, Shoba A. Navai, Malcolm K. Brenner, Adrian P. Gee, Birju Mehta, Huimin Zhang
Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Refractory metastatic rhabdomyosarcoma is largely incurable. Here we analyze the response of a child with refractory bone marrow metastatic rhabdomyosarcoma to autologous HER2 CAR T cells. Three cycles of HER2 CAR T cells given after lymphodepleting
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ba4621fb359fbc26a85390ff0a183f
https://doi.org/10.1038/s41467-020-17175-8
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6
Abstract 6605: Functional screening of bispecific CAR ectodomains targeting HER2 and GD2 in melanoma
Autor: Nabil Ahmed, Zakaria Grada, Amanda Wakefield, Ankita Shree, Sujith K. Joseph, Kristen Fousek, Shoba A. Navai, Meenakshi Hegde, Pretty R. Mathew
Publikováno v: Cancer Research. 80:6605-6605
We describe the development of targeted immunotherapy using a bispecific chimeric antigen receptor (CAR) modified T-cell directed against the tumor associated antigens, human epidermal growth factor receptor 2 (HER2) and the disialoganglioside GD2, s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e6327e153abaff534d5369e0a8f2ddd7
https://doi.org/10.1158/1538-7445.am2020-6605
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7
Malignant melanoma incidence among children and adolescents in Texas and SEER 13, 1995–2013
Autor: Heather E. Danysh, Shoba A. Navai, Michael E. Scheurer, Rajkumar Venkatramani, Raegan D. Hunt
Publikováno v: Pediatr Blood Cancer
BACKGROUND Epidemiological knowledge and predictors of melanoma among children and adolescents in multiethnic populations are limited. PROCEDURE Using data from the Texas Cancer Registry (TCR) and the Surveillance, Epidemiology, and End Results (SEER
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f6b828ed3b2831f4828529be8cf6e8a
https://doi.org/10.1002/pbc.27648
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8
Targeting the tumour profile using broad spectrum chimaeric antigen receptor T-cells
Autor: Shoba A. Navai, Nabil Ahmed
Publikováno v: Biochemical Society transactions. 44(2)
A variety of distinct and redundant mechanisms support tumour propagation and survival. Tumour parenchyma consists of a variety of geographically diverse cells with varying genetic expression among subclonal populations. Additionally, the solid tumou
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580a21e6ec7ca7f6ad411017e4720652
https://pubmed.ncbi.nlm.nih.gov/27068945
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9
Abstract A50: Trivalent CAR T cells mitigate CD19-negative relapse and improve tumor control in primary pre-B cell acute lymphoblastic leukemia (B-ALL)
Autor: Albert Jang, Hye Na Kim, Jonathan Kirzner, Nabil Ahmed, Heba Samaha, Meenakshi Hegde, Tiara T. Byrd, Xingyue An, Nora Heisterkamp, Junji Watanabe, Kristen Fousek, Navin Varadarajan, Matthew L. Baker, Hisham Abdel-Azim, Shoba A. Navai, Sujith K. Joseph, Ann George
Publikováno v: Cancer Immunology Research. 6:A50-A50
B-acute lymphoblastic leukemia (B-ALL) is the most common malignancy in children, and limited treatment options exist for patients with relapsed or refractory disease. Cellular immunotherapy, specifically chimeric antigen receptor (CAR) T cells targe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ef12917c1fd5e7c6017f13ec2809fa7
https://doi.org/10.1158/2326-6074.tumimm17-a50
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10
Targeting CD19-negative relapsed B-acute lymphoblastic leukemia using trivalent CAR T cells
Autor: Hye Na Kim, Xingyue An, Matthew L. Baker, Yong-Mi Kim, Shoba A. Navai, Hisham Abdel-Azim, Albert Jang, Tiara T. Byrd, Meenakshi Hegde, Nabil Ahmed, Kristen Fousek, Junji Watanabe, Sujith K. Joseph, Ann George, Navin Varadarajan, Nora Heisterkamp, Heba Samaha
Publikováno v: Journal of Clinical Oncology. 36:121-121
121 Background: Chimeric antigen receptor (CAR) T cells targeting CD19 have shown remarkable efficacy in treating relapsed B cell acute lymphoblastic leukemia (B-ALL). However, recent reports show that up to 40% of patients who relapse after CD19 CAR
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a0ec987efd99ce79b00779a60b07656
https://doi.org/10.1200/jco.2018.36.5_suppl.121
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