Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Sho Morioka"'
Autor:
Takeshi Chida, Yuji Ishida, Sho Morioka, Go Sugahara, Christine Han, Bill Lam, Chihiro Yamasaki, Remi Sugahara, Meng Li, Yasuhito Tanaka, T. Jake Liang, Chise Tateno, Takeshi Saito
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
Hepatitis delta virus (HDV), a satellite virus of HBV, is regarded as the most severe type of hepatitis virus because of the substantial morbidity and mortality. The IFN system is the first line of defense against viral infections and an essential el
Externí odkaz:
https://doaj.org/article/608b3b9284e2485ab23afc6503eddeab
Autor:
Claudia M. Rival, Wenhao Xu, Laura S. Shankman, Sho Morioka, Sanja Arandjelovic, Chang Sup Lee, Karen M. Wheeler, Ryan P. Smith, Lisa B. Haney, Brant E. Isakson, Scott Purcell, Jeffrey J. Lysiak, Kodi S. Ravichandran
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Izumo and Juno are receptors on sperm and eggs respectively required for fusion, but other factors for sperm-egg fusion are poorly studied. Here, the authors report that phosphatidylserine, found mainly on cells marked for death, is also present on m
Externí odkaz:
https://doaj.org/article/89356b6243dc4c859d4c2eaf9ae0cf51
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Programmed cell death (PCD) occurs in several forms including apoptosis and necroptosis. Apoptosis is executed by the activation of caspases, while necroptosis is dependent on the receptor interacting protein kinase 3 (RIPK3). Precise contro
Externí odkaz:
https://doaj.org/article/2056cc721a4243bf8b14c0331b0af806
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94982 (2014)
Macrophages play diverse roles in tissue homeostasis and immunity, and canonically activated macrophages are critically associated with acute inflammatory responses. It is known that activated macrophages undergo cell death after transient activation
Externí odkaz:
https://doaj.org/article/32ddf83edec040e9b64ee154f41baa1e
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88037 (2014)
The liver is the first line of defense from environmental stressors in that hepatocytes respond to and metabolize them. Hence, hepatocytes can be damaged by stressors. Protection against hepatic cell damage and cell death is important for liver funct
Externí odkaz:
https://doaj.org/article/7bca9e756e6b41b79209b9dd26acd41b
Supplemental legend from CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer
Autor:
Todd W. Bauer, J. Thomas Parsons, Kodi S. Ravichandran, Craig L. Slingluff, Timothy N. J. Bullock, Jesse B. Persily, Matthew G. Mullen, Sarbajeet Nagdas, Bernadette J. Goudreau, Sho Morioka, Sara J. Adair, Timothy E. Newhook, Alex D. Michaels
Supplemental legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ae90723b16bb6d9c0fa3c8ab5df2c9
https://doi.org/10.1158/1078-0432.22460652.v1
https://doi.org/10.1158/1078-0432.22460652.v1
Autor:
Todd W. Bauer, J. Thomas Parsons, Kodi S. Ravichandran, Craig L. Slingluff, Timothy N. J. Bullock, Jesse B. Persily, Matthew G. Mullen, Sarbajeet Nagdas, Bernadette J. Goudreau, Sho Morioka, Sara J. Adair, Timothy E. Newhook, Alex D. Michaels
Purpose: Patients with pancreatic ductal adenocarcinoma (PDAC) who undergo surgical resection and adjuvant chemotherapy have an expected survival of only 2 years due to disease recurrence, frequently in the liver. We investigated the role of liver ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939bd162b8d708e254072e5725e6b404
https://doi.org/10.1158/1078-0432.c.6524556.v1
https://doi.org/10.1158/1078-0432.c.6524556.v1
Publikováno v:
Nephron
Various forms of cell death have been identified, and billions of cells die during development and daily in adult organisms. Clearing dead cells and associated cellular debris is an integral part of tissue homeostasis. While diverse types of phagocyt
Autor:
Michael H, Raymond, Andrew J, Davidson, Yi, Shen, Daniel R, Tudor, Christopher D, Lucas, Sho, Morioka, Justin S A, Perry, Julia, Krapivkina, David, Perrais, Linus J, Schumacher, Robert E, Campbell, Will, Wood, Kodi S, Ravichandran
Publikováno v:
Science (New York, N.Y.). 375(6585)
Apoptosis of cells and their subsequent removal through efferocytosis occurs in nearly all tissues during development, homeostasis, and disease. However, it has been difficult to track cell death and subsequent corpse removal in vivo. We developed a
Autor:
Alexander S. Krupnick, Kodi S. Ravichandran, Scott F. Walk, Christopher B. Medina, Bart Ghesquière, Yizhan Guo, Sanja Arandjelovic, Sho Morioka, Parul Mehrotra, Brady J. Barron, Justin S. A. Perry, Ulrike Lorenz
Publikováno v:
Nature
Caspase-dependent apoptosis accounts for approximately 90% of homeostatic cell turnover in the body1, and regulates inflammation, cell proliferation, and tissue regeneration2–4. How apoptotic cells mediate such diverse effects is not fully understo