Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Sho Kitamoto"'
Autor:
Yijie Guo, Sho Kitamoto, Gustavo Caballero-Flores, Yeji Kim, Daisuke Watanabe, Kohei Sugihara, Gabriel Núñez, Christopher J. Alteri, Naohiro Inohara, Nobuhiko Kamada
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTThe ectopic gut colonization by orally derived pathobionts has been implicated in the pathogenesis of various gastrointestinal diseases, including inflammatory bowel disease (IBD). For example, gut colonization by orally derived Klebsiella sp
Externí odkaz:
https://doaj.org/article/89d31e824047448388eaeea4d7819934
Autor:
Kazuki Nakai, Hancheng Lin, Shotaro Yamano, Shinya Tanaka, Sho Kitamoto, Hitoshi Saitoh, Kenta Sakuma, Junpei Kurauchi, Eilma Akter, Masamitsu Konno, Kojiro Ishibashi, Ryo Kamata, Akihiro Ohashi, Jun Koseki, Hirotaka Takahashi, Hideshi Yokoyama, Yukihiro Shiraki, Atsushi Enomoto, Sohei Abe, Yoku Hayakawa, Tetsuo Ushiku, Michihiro Mutoh, Yasuyuki Fujita, Shunsuke Kon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Normal epithelial cells exert their competitive advantage over RasV12-transformed cells and eliminate them into the apical lumen via cell competition. However, the internal or external factors that compromise cell competition and provoke car
Externí odkaz:
https://doaj.org/article/6f44e420616648b8bbcf9f4de854cbbb
Autor:
Sho Kitamoto, Nobuhiko Kamada
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-9 (2023)
Abstract Inflammatory bowel disease (IBD) is a multifactorial intractable intestinal disease. Focusing on only one facet of the pathogenesis of IBD is insufficient to fully capture the complexity of the disease, and results in limited advance in clin
Externí odkaz:
https://doaj.org/article/0163d6411a7b4af8a022a77951d77c83
Autor:
Rika Tanaka, Jin Imai, Hitoshi Tsugawa, Karl Bil Eap, Masaki Yazawa, Motoki Kaneko, Masashi Ohno, Kohei Sugihara, Sho Kitamoto, Hiroko Nagao-Kitamoto, Nicolas Barnich, Masashi Matsushima, Takayoshi Suzuki, Tatehiro Kagawa, Yasuhiro Nishizaki, Hidekazu Suzuki, Nobuhiko Kamada, Katsuto Hozumi
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Background and aimAdherent-invasive E. coli (AIEC) has been identified as a pathobiont associated with Crohn’s disease (CD), that prefers to grow in inflammatory conditions. Although the colonization by AIEC is implicated in the progression of the
Externí odkaz:
https://doaj.org/article/bdfef7b8bffb42bdafe3be6e4e880eba
Autor:
Jin Imai, Hitoshi Ichikawa, Sho Kitamoto, Jonathan L. Golob, Motoki Kaneko, Junko Nagata, Miho Takahashi, Merritt G. Gillilland III, Rika Tanaka, Hiroko Nagao-Kitamoto, Atsushi Hayashi, Kohei Sugihara, Shrinivas Bishu, Shingo Tsuda, Hiroyuki Ito, Seiichiro Kojima, Kazunari Karakida, Masashi Matsushima, Takayoshi Suzuki, Katsuto Hozumi, Norihito Watanabe, William V. Giannobile, Takayuki Shirai, Hidekazu Suzuki, Nobuhiko Kamada
Publikováno v:
JCI Insight, Vol 6, Iss 23 (2021)
Oral conditions are relatively common in patients with inflammatory bowel disease (IBD). However, the contribution of oral maladies to gut inflammation remains unexplored. Here, we investigated the effect of periodontitis on disease phenotypes of pat
Externí odkaz:
https://doaj.org/article/6805a612c28d497eaa0707b7c8d4ff9f
Publikováno v:
Gut Microbes, Vol 12, Iss 1 (2020)
There are 100 trillion diverse bacterial residents in the mammalian gut. Commensal bacterial species/strains cooperate and compete with each other to establish a well-balanced community, crucial for the maintenance of host health. Pathogenic bacteria
Externí odkaz:
https://doaj.org/article/2c0e81a6aad04719b2d359672a086bf4
Autor:
Hirotaka Watanabe, Kojiro Ishibashi, Hiroki Mano, Sho Kitamoto, Nanami Sato, Kazuya Hoshiba, Mugihiko Kato, Fumihiko Matsuzawa, Yasuto Takeuchi, Takanobu Shirai, Susumu Ishikawa, Yuka Morioka, Toshiaki Imagawa, Kazuyasu Sakaguchi, Suguru Yonezawa, Shunsuke Kon, Yasuyuki Fujita
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3721-3729 (2018)
Summary: p53 is a tumor suppressor protein, and its missense mutations are frequently found in human cancers. During the multi-step progression of cancer, p53 mutations generally accumulate at the mid or late stage, but not in the early stage, and th
Externí odkaz:
https://doaj.org/article/7b3d5f86dea4489d8d609ac4b73d0b9d
Autor:
Hiroko Nagao-Kitamoto, Andrew B. Shreiner, Merritt G. Gillilland, III, Sho Kitamoto, Chiharu Ishii, Akiyoshi Hirayama, Peter Kuffa, Mohamad El-Zaatari, Helmut Grasberger, Anna M. Seekatz, Peter D.R. Higgins, Vincent B. Young, Shinji Fukuda, John Y. Kao, Nobuhiko Kamada
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 4, Pp 468-481 (2016)
Background & Aims: Gut dysbiosis is closely involved in the pathogenesis of inflammatory bowel disease (IBD). However, it remains unclear whether IBD-associated gut dysbiosis contributes to disease pathogenesis or is merely secondary to intestinal in
Externí odkaz:
https://doaj.org/article/3fc493a99c8344008e1daab2da6889ba
Publikováno v:
Intestinal Research, Vol 14, Iss 2, Pp 127-138 (2016)
The gastrointestinal (GI) tract is colonized by a dense community of commensal microorganisms referred to as the gut microbiota. The gut microbiota and the host have co-evolved, and they engage in a myriad of immunogenic and metabolic interactions. T
Externí odkaz:
https://doaj.org/article/ba784f57503c462aa06e10865fac71df
Autor:
Junichiro En, Sho Kitamoto, Akira Kawashima, Suguru Yonezawa, Yoshito Kishi, Norihisa Ishii, Masamichi Goto
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 8, p e0005834 (2017)
Buruli ulcer is a chronic painless skin disease caused by Mycobacterium ulcerans. The local nerve damage induced by M. ulcerans invasion is similar to the nerve damage evoked by the injection of mycolactone in a Buruli ulcer mouse model. In order to
Externí odkaz:
https://doaj.org/article/361bc656c9f5454c94ff3f757c0d60ee