Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sho Anzai"'
Autor:
Reiko Kuno, Go Ito, Ami Kawamoto, Yui Hiraguri, Hady Yuki Sugihara, Sayaka Takeoka, Sayaka Nagata, Junichi Takahashi, Mao Tsuchiya, Sho Anzai, Tomohiro Mizutani, Hiromichi Shimizu, Shiro Yui, Shigeru Oshima, Kiichiro Tsuchiya, Mamoru Watanabe, Ryuichi Okamoto
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss , Pp 100906- (2021)
Notch signaling is activated in the intestinal epithelial cells (IECs) of patients with inflammatory bowel disease (IBD), and contributes to mucosal regeneration. Our previous study indicated that TNF-α and Notch signaling may synergistically promot
Externí odkaz:
https://doaj.org/article/0a375b89ba1e4c71a4f4c238859107d9
Contribution of ATOH1+ Cells to the Homeostasis, Repair, and Tumorigenesis of the Colonic Epithelium
Autor:
Fumiaki Ishibashi, Hiromichi Shimizu, Toru Nakata, Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Sho Anzai, Reiko Kuno, Sayaka Nagata, Go Ito, Tatsuro Murano, Tomohiro Mizutani, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Mamoru Watanabe, Ryuichi Okamoto
Publikováno v:
Stem Cell Reports, Vol 10, Iss 1, Pp 27-42 (2018)
Summary: ATOH1 is a master transcription factor for the secretory lineage differentiation of intestinal epithelial cells (IECs). However, the comprehensive contribution of ATOH1+ secretory lineage IECs to the homeostasis, repair, and tumorigenesis of
Externí odkaz:
https://doaj.org/article/87734184b9144dfba2a2a9114587cdcd
Autor:
Toru Nakata, Hiromichi Shimizu, Sayaka Nagata, Go Ito, Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Fumiaki Ishibashi, Reiko Kuno, Sho Anzai, Tatsuro Murano, Tomohiro Mizutani, Shigeru Oshima, Kiichiro Tsuchiya, Tetsuya Nakamura, Katsuto Hozumi, Mamoru Watanabe, Ryuichi Okamoto
Publikováno v:
Data in Brief, Vol 10, Iss C, Pp 551-556 (2017)
The data on the immunohistochemical analysis of conditional Notch ligand knockout mice is presented. Targeted deletion of Jag1, Dll1, Dll4, or Dll1 plus Dll4 in Lgr5+ve cells was induced by a Cre-mediated gene recombination, and differentiation or pr
Externí odkaz:
https://doaj.org/article/14cf8246e42340d88a2c01e46742625d
Autor:
Mikinori Kataoka, Sho Anzai, Tomoaki Shirasaki, Hidekazu Ikemiyagi, Takashi Fujii, Kazuhisa Mabuchi, Shinji Suzuki, Masashi Yoshida, Takashi Kawai, Masaki Kitajima
Publikováno v:
Endoscopy International Open, Vol 03, Iss 02, Pp E113-E117 (2015)
Background and aims: Endoscopic submucosal dissection (ESD) was developed in Japan and has been performed on many patients with early stage esophageal cancer; however quality of life in patients with postoperative stricture is drastically decreased a
Externí odkaz:
https://doaj.org/article/488906f6f1654d12965965481bfbf815
Autor:
Minami Hama, Sho Anzai, Junichi Takahashi, Hady Yuki Sugihara, Shigeru Oshima, Tomohiro Mizutani, M. Tsuchiya, Hiromichi Shimizu, Sayaka Nagata, Go Ito, Mamoru Watanabe, Yui Hiraguri, Kiichiro Tsuchiya, Sayaka Takeoka, Ryuichi Okamoto, Shiro Yui, Reiko Kuno, Ami Kawamoto, Kohei Suzuki
Publikováno v:
Biochemical and Biophysical Research Communications. 542:40-47
Inflammatory bowel disease (IBD) comprises two major subtypes, ulcerative colitis (UC) and Crohn's disease, which are multifactorial diseases that may develop due to genetic susceptibility, dysbiosis, or environmental factors. Environmental triggers
Autor:
Shiro Yui, Hiromichi Shimizu, Ami Kawamoto, Satoshi Watanabe, Mamoru Watanabe, Sayaka Nagata, Hady Yuki Sugihara, Junichi Takahashi, Shigeru Oshima, Sakurako Kobayashi, Yui Hiraguri, Sayaka Takeoka, Sho Anzai, Ryuichi Okamoto, Reiko Kuno, Kohei Suzuki, Mao Kawai
Publikováno v:
Biochemical and Biophysical Research Communications. 524:533-541
The early-phase wound repair response of the intestinal epithelium is characterized by rapid and organized cell migration. This response is regulated by several humoral factors, including TGF-β. However, due to a lack of appropriate models, the prec
Autor:
Sayaka Nagata, Go Ito, Kiichiro Tsuchiya, Ryuichi Okamoto, Hiromichi Shimizu, M. Tsuchiya, Ami Kawamoto, Sho Anzai, Yui Hiraguri, Reiko Kuno, Tomohiro Mizutani, Hady Yuki Sugihara, Junichi Takahashi, Shigeru Oshima, Sayaka Takeoka, Shiro Yui, Mamoru Watanabe
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss, Pp 100906-(2021)
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports
Notch signaling is activated in the intestinal epithelial cells (IECs) of patients with inflammatory bowel disease (IBD), and contributes to mucosal regeneration. Our previous study indicated that TNF-α and Notch signaling may synergistically promot
Autor:
Ryuichi Okamoto, Reiko Kuno, Kiichiro Tsuchiya, Daichi Nogawa, Kouhei Yamamoto, Sayaka Nagata, Kohei Suzuki, Minami Hama, Hiromichi Shimizu, Junichi Takahashi, Shigeru Oshima, Masanobu Kitagawa, Mao Kawai, Yui Hiraguri, Ami Kawamoto, Tetsuya Nakamura, Shiro Yui, Kazuo Ohtsuka, Mamoru Watanabe, Sho Anzai
Publikováno v:
Journal of Crohn's and Colitis. 13:495-509
Background and aims The intestinal epithelium of inflammatory bowel disease [IBD] patients is exposed to various pro-inflammatory cytokines, most notably tumour necrosis factor alpha [TNF-α]. We have previously shown that the Notch signalling pathwa
Autor:
Hiromichi Shimizu, Sayaka Nagata, Konomi Kuwabara, Fumiaki Ishibashi, Ryuichi Okamoto, Satoru Fujii, Kento Takenaka, Tatsuro Murano, Ami Kawamoto, Reiko Kuno, Sho Anzai, Kiichiro Tsuchiya, Yui Hiraguri, Kazuo Ohtsuka, Kohei Suzuki, Minami Hama, Shiro Yui, Junichi Takahashi, Mamoru Watanabe, Toru Nakata, Tetsuya Nakamura, Go Ito
Publikováno v:
Journal of Gastroenterology
Background Intestinal stem cells (ISCs) play indispensable roles in the maintenance of homeostasis, and also in the regeneration of the damaged intestinal epithelia. However, whether the inflammatory environment of Crohn’s disease (CD) affects prop
Contribution of ATOH1+ Cells to the Homeostasis, Repair, and Tumorigenesis of the Colonic Epithelium
Autor:
Tatsuro Murano, Ami Kawamoto, Shigeru Oshima, Tetsuya Nakamura, Kiichiro Tsuchiya, Sayaka Nagata, Fumiaki Ishibashi, Ryuichi Okamoto, Hiromichi Shimizu, Mamoru Watanabe, Go Ito, Reiko Kuno, Sho Anzai, Toru Nakata, Kohei Suzuki, Satoru Fujii, Tomohiro Mizutani
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 10, Iss 1, Pp 27-42 (2018)
Stem Cell Reports, Vol 10, Iss 1, Pp 27-42 (2018)
Summary ATOH1 is a master transcription factor for the secretory lineage differentiation of intestinal epithelial cells (IECs). However, the comprehensive contribution of ATOH1+ secretory lineage IECs to the homeostasis, repair, and tumorigenesis of