Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Shmuel Yitzhaki"'
Autor:
Noam Cohen, Yaron Vagima, Odelia Mouhadeb, Einat Toister, Hila Gutman, Shlomi Lazar, Avital Jayson, Arbel Artzy-Schnirman, Josué Sznitman, Arie Ordentlich, Shmuel Yitzhaki, Dror Seliktar, Emanuelle Mamroud, Eyal Epstein
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Recent advances in the field of cell therapy have proposed new solutions for tissue repair and regeneration using various cell delivery approaches. Here we studied ex vivo a novel topical delivery system of encapsulated cells in hybrid polyethylene g
Externí odkaz:
https://doaj.org/article/c8b304ced3fd49f7843aefe214049d08
Autor:
Ronit Rosenfeld, Tal Noy-Porat, Adva Mechaly, Efi Makdasi, Yinon Levy, Ron Alcalay, Reut Falach, Moshe Aftalion, Eyal Epstein, David Gur, Theodor Chitlaru, Einat B. Vitner, Sharon Melamed, Boaz Politi, Ayelet Zauberman, Shirley Lazar, Adi Beth-Din, Yentl Evgy, Shmuel Yitzhaki, Shmuel C. Shapira, Tomer Israely, Ohad Mazor
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Here, using the K18-hACE2 transgenic mice model, the authors report the in vivo efficacy of a fully human neutralizing antibody against SARS-CoV-2 and show that when administered before or up to 3 days post infection, treated mice do not exhibit dise
Externí odkaz:
https://doaj.org/article/46809b3d714542f1b041f07ea3d49be0
Autor:
Ofir Schuster, Anat Zvi, Osnat Rosen, Hagit Achdout, Amir Ben-Shmuel, Ohad Shifman, Shmuel Yitzhaki, Orly Laskar, Liron Feldberg
Publikováno v:
ACS Omega, Vol 6, Iss 5, Pp 3525-3534 (2021)
Externí odkaz:
https://doaj.org/article/7505138125db4a68b41c959f8dd97bf2
Autor:
Yfat Yahalom-Ronen, Hadas Tamir, Sharon Melamed, Boaz Politi, Ohad Shifman, Hagit Achdout, Einat B. Vitner, Ofir Israeli, Elad Milrot, Dana Stein, Inbar Cohen-Gihon, Shlomi Lazar, Hila Gutman, Itai Glinert, Lilach Cherry, Yaron Vagima, Shirley Lazar, Shay Weiss, Amir Ben-Shmuel, Roy Avraham, Reut Puni, Edith Lupu, Elad Bar-David, Assa Sittner, Noam Erez, Ran Zichel, Emanuelle Mamroud, Ohad Mazor, Haim Levy, Orly Laskar, Shmuel Yitzhaki, Shmuel C. Shapira, Anat Zvi, Adi Beth-Din, Nir Paran, Tomer Israely
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Here, the authors generate a replication-competent VSV based vaccine expressing SARS-CoV-2 spike protein and show protection in the hamster model with one dose. Analysis of the antibody response in mice shows induction of neutralizing antibodies and
Externí odkaz:
https://doaj.org/article/c9dbfd8736364f25b7884f0d5634e9e1
Autor:
Tal Noy-Porat, Efi Makdasi, Ron Alcalay, Adva Mechaly, Yinon Levy, Adi Bercovich-Kinori, Ayelet Zauberman, Hadas Tamir, Yfat Yahalom-Ronen, Ma’ayan Israeli, Eyal Epstein, Hagit Achdout, Sharon Melamed, Theodor Chitlaru, Shay Weiss, Eldar Peretz, Osnat Rosen, Nir Paran, Shmuel Yitzhaki, Shmuel C. Shapira, Tomer Israely, Ohad Mazor, Ronit Rosenfeld
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
Here, Noy-Porat, Makdasi et al. report the isolation of a panel of neutralizing mAbs selected against SARS-CoV-2 receptor-binding domain (RBD) from a phage display library constructed based on patient samples collected in the acute phase of the disea
Externí odkaz:
https://doaj.org/article/b2261c0965d74199a91b395d6e6b9e4c
Autor:
Sharon Melamed, Boaz Politi, Ettie Grauer, Hagit Achdout, Moshe Aftalion, David Gur, Hadas Tamir, Yfat Yahalom-Ronen, Shlomy Maimon, Efi Yitzhak, Shay Weiss, Amir Rosner, Noam Erez, Shmuel Yitzhaki, Shmuel C Shapira, Nir Paran, Emanuelle Mamroud, Yaron Vagima, Tomer Israely
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
The COVID-19 pandemic initiated a worldwide race toward the development of treatments and vaccines. Small animal models included the Syrian golden hamster and the K18-hACE2 mice infected with SARS-CoV-2 to display a disease state with some aspects of
Externí odkaz:
https://doaj.org/article/374b2caa6c0a4cddb280a3a1453707f5
Autor:
Ofir Israeli, Adi Beth-Din, Nir Paran, Dana Stein, Shirley Lazar, Shay Weiss, Elad Milrot, Yafit Atiya-Nasagi, Shmuel Yitzhaki, Orly Laskar, Ofir Schuster
Publikováno v:
International Journal of Infectious Diseases, Vol 99, Iss , Pp 352-354 (2020)
The genetic identification of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is based on viral RNA extraction prior to RT-qPCR assay. However, recent studies have supported the elimination of the extraction step. This study was performe
Externí odkaz:
https://doaj.org/article/f8220712ac3a43c9bbbc4aadd4ca32d8
Autor:
Noam Erez, Hagit Achdout, Elad Milrot, Yuval Schwartz, Yonit Wiener-Well, Nir Paran, Boaz Politi, Hadas Tamir, Tomer Israely, Shay Weiss, Adi Beth-Din, Ohad Shifman, Ofir Israeli, Shmuel Yitzhaki, Shmuel C. Shapira, Sharon Melamed, Eli Schwartz
Publikováno v:
Emerging Infectious Diseases, Vol 25, Iss 5, Pp 980-983 (2019)
We report a case of monkeypox in a man who returned from Nigeria to Israel in 2018. Virus was detected in pustule swabs by transmission electron microscopy and PCR and confirmed by immunofluorescence assay, tissue culture, and ELISA. The West Africa
Externí odkaz:
https://doaj.org/article/4553fdf9dbc64c76884ca955837d5438
Autor:
Reut Falach, Liat Bar-On, Shlomi Lazar, Tamar Kadar, Ohad Mazor, Moshe Aftalion, David Gur, Yentl Evgy, Ohad Shifman, Tamar Aminov, Ofir Israeli, Inbar Cohen-Gihon, Galia Zaide, Hila Gutman, Yaron Vagima, Efi Makdasi, Dana Stein, Ronit Rosenfeld, Ron Alcalay, Eran Zahavy, Haim Levy, Itai Glinert, Amir Ben-Shmuel, Tomer Israely, Sharon Melamed, Boaz Politi, Hagit Achdout, Shmuel Yitzhaki, Chanoch Kronman, Tamar Sabo
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
Mice are normally unaffected by SARS coronavirus 2 (SARS-CoV-2) infection since the virus does not bind effectively to the murine version of the angiotensin-converting enzyme 2 (ACE2) receptor molecule. Here, we report that induced mild pulmonary mor
Externí odkaz:
https://doaj.org/article/f15ac9c77afc452ba0b7c4173a5bfbfe
Autor:
Tal Noy-Porat, Adva Mechaly, Yinon Levy, Efi Makdasi, Ron Alcalay, David Gur, Moshe Aftalion, Reut Falach, Shani Leviatan Ben-Arye, Shirley Lazar, Ayelet Zauberman, Eyal Epstein, Theodor Chitlaru, Shay Weiss, Hagit Achdout, Jonathan D. Edgeworth, Raghavendra Kikkeri, Hai Yu, Xi Chen, Shmuel Yitzhaki, Shmuel C. Shapira, Vered Padler-Karavani, Ohad Mazor, Ronit Rosenfeld
Publikováno v:
iScience, Vol 24, Iss 5, Pp 102479- (2021)
Summary: Neutralizing antibodies represent a valuable therapeutic approach to countermeasure the current COVID-19 pandemic. Emergence of SARS-CoV-2 variants emphasizes the notion that antibody treatments need to rely on highly neutralizing monoclonal
Externí odkaz:
https://doaj.org/article/5be2c18d8ba44814aa7c3af9cabd005d