Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shmool, TA"'
Publikováno v:
JACS Au. 2:2068-2080
Novel drug candidates are continuously being developed to combat the most life-threatening diseases; however, many promising protein therapeutics are dropped from the pipeline. During biological and industrial processes, protein therapeutics are expo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156a7183144bdff6d17c957cdf55d7b5
https://doi.org/10.1021/jacsau.2c00356
https://doi.org/10.1021/jacsau.2c00356
Autor:
Shmool, TA, Martin, LK, Bui-Le, L, Moya-Ramirez, I, Kotidis, P, Matthews, RP, Venter, GA, Kontoravdi, C, Polizzi, KM, Hallett, JP
Publikováno v:
Chemical Science
Understanding protein folding in different environmental conditions is fundamentally important for predicting protein structures and developing innovative antibody formulations. While the thermodynamics and kinetics of folding and unfolding have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7185aa8643dad6a9bea1cfa5cce39801
https://doi.org/10.1039/d1sc02520a
https://doi.org/10.1039/d1sc02520a
Autor:
Shmool, TA, Zeitler, JA
The mechanical properties of an amorphous copolymer are directly related to the dynamic processes occurring at the molecular level.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a640a56a27a918962ceeaf84e6f76321
Biodegradable poly lactic-co-glycolic acid (PLGA) microspheres can be used to encapsulate peptide and offer a promising drug delivery vehicle. In this work we investigate the dynamics of PLGA microspheres prepared by freeze-drying and the molecular m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ff27338bc376afb3ef82e0c518f0d7c
Autor:
Shmool TA; Department of Chemical Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ, U.K., Martin LK; Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, U.K., Jirkas A; Department of Chemical Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ, U.K., Matthews RP; Department of Chemical Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ, U.K.; Department of Bioscience, School of Health, Sports and Bioscience, University of East London, Stratford, London E15 4LZ, U.K., Constantinou AP; Department of Materials, Imperial College London, South Kensington Campus, London SW7 2AZ, U.K., Vadukul DM; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, U.K., Georgiou TK; Department of Materials, Imperial College London, South Kensington Campus, London SW7 2AZ, U.K., Aprile FA; Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, U.K.; Institute of Chemical Biology, Molecular Sciences Research Hub, Imperial College London, London W12 0BZ, U.K., Hallett JP; Department of Chemical Engineering, Imperial College London, South Kensington Campus, London SW7 2AZ, U.K.
Publikováno v:
Chemistry of materials : a publication of the American Chemical Society [Chem Mater] 2023 Jul 20; Vol. 35 (15), pp. 5798-5808. Date of Electronic Publication: 2023 Jul 20 (Print Publication: 2023).
Autor:
Stephens AD; Department of Chemical Engineering and Biotechnology University of Cambridge UK., Kölbel J; Department of Chemical Engineering and Biotechnology University of Cambridge UK., Moons R; Department of Chemistry University of Antwerp Belgium., Chung CW; Department of Chemical Engineering and Biotechnology University of Cambridge UK., Ruggiero MT; Department of Chemical Engineering and Biotechnology University of Cambridge UK.; Department of Chemistry University of Vermont USA., Mahmoudi N; ISIS STFC Rutherford Appleton Laboratory UK., Shmool TA; Department of Chemical Engineering and Biotechnology University of Cambridge UK., McCoy TM; Department of Chemical Engineering and Biotechnology University of Cambridge UK., Nietlispach D; Department of Biochemistry University of Cambridge UK., Routh AF; Department of Chemical Engineering and Biotechnology University of Cambridge UK., Sobott F; Department of Chemistry University of Antwerp Belgium.; The Astbury Centre for Structural Molecular Biology University of Leeds UK., Zeitler JA; Department of Chemical Engineering and Biotechnology University of Cambridge UK., Kaminski Schierle GS; Department of Chemical Engineering and Biotechnology University of Cambridge UK.
Publikováno v:
Angewandte Chemie (Weinheim an der Bergstrasse, Germany) [Angew Chem Weinheim Bergstr Ger] 2023 Feb 06; Vol. 135 (7), pp. e202212063. Date of Electronic Publication: 2023 Jan 12.
Autor:
Shmool TA; Department of Chemical Engineering, Imperial College London London SW7 2AZ UK j.hallett@imperial.ac.uk +44 (0)20 7594 5388., Martin LK; Department of Chemical Engineering, Imperial College London London SW7 2AZ UK j.hallett@imperial.ac.uk +44 (0)20 7594 5388.; Imperial College Centre for Synthetic Biology, Imperial College London London SW7 2AZ UK., Clarke CJ; Department of Chemical Engineering, Imperial College London London SW7 2AZ UK j.hallett@imperial.ac.uk +44 (0)20 7594 5388., Bui-Le L; Department of Chemical Engineering, Imperial College London London SW7 2AZ UK j.hallett@imperial.ac.uk +44 (0)20 7594 5388., Polizzi KM; Department of Chemical Engineering, Imperial College London London SW7 2AZ UK j.hallett@imperial.ac.uk +44 (0)20 7594 5388.; Imperial College Centre for Synthetic Biology, Imperial College London London SW7 2AZ UK., Hallett JP; Department of Chemical Engineering, Imperial College London London SW7 2AZ UK j.hallett@imperial.ac.uk +44 (0)20 7594 5388.
Publikováno v:
Chemical science [Chem Sci] 2020 Oct 23; Vol. 12 (1), pp. 196-209. Date of Electronic Publication: 2020 Oct 23.
Autor:
Batens M; Drug Delivery and Disposition, KU Leuven, Leuven, Belgium. guy.vandenmooter@kuleuven.be., Shmool TA, Massant J, Zeitler JA, Van den Mooter G
Publikováno v:
Physical chemistry chemical physics : PCCP [Phys Chem Chem Phys] 2020 Aug 14; Vol. 22 (30), pp. 17247-17254. Date of Electronic Publication: 2020 Jul 20.
Autor:
Shmool TA; Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom., Batens M; Drug Delivery and Disposition, KU Leuven, Leuven, Belgium., Massant J; Biological Formulation Development, UCB Pharma, Braine l'Alleud, Belgium., Van den Mooter G; Drug Delivery and Disposition, KU Leuven, Leuven, Belgium., Zeitler JA; Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom. Electronic address: jaz22@cam.ac.uk.
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2019 Nov; Vol. 144, pp. 244-251. Date of Electronic Publication: 2019 Sep 20.
Autor:
Shmool TA; Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge CB3 0AS, United Kingdom., Woodhams PJ; Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge CB3 0AS, United Kingdom., Leutzsch M; Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge CB3 0AS, United Kingdom., Stephens AD; Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge CB3 0AS, United Kingdom., Gaimann MU; Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge CB3 0AS, United Kingdom., Mantle MD; Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge CB3 0AS, United Kingdom., Kaminski Schierle GS; Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge CB3 0AS, United Kingdom., van der Walle CF; Biopharmaceutical Development, AstraZeneca, Granta Park, Cambridge CB21 6GH, United Kingdom., Zeitler JA; Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge CB3 0AS, United Kingdom.
Publikováno v:
International journal of pharmaceutics: X [Int J Pharm X] 2019 Jul 08; Vol. 1, pp. 100022. Date of Electronic Publication: 2019 Jul 08 (Print Publication: 2019).