Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Shlomo Finkin"'
Autor:
Allison J. Greaney, Tyler N. Starr, Christopher O. Barnes, Yiska Weisblum, Fabian Schmidt, Marina Caskey, Christian Gaebler, Alice Cho, Marianna Agudelo, Shlomo Finkin, Zijun Wang, Daniel Poston, Frauke Muecksch, Theodora Hatziioannou, Paul D. Bieniasz, Davide F. Robbiani, Michel C. Nussenzweig, Pamela J. Bjorkman, Jesse D. Bloom
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Emerging SARS-CoV-2 mutants may escape neutralization by antibodies. Here, the authors use deep mutational scanning to identify mutations in the RBD that escape human monoclonal antibodies or convalescent plasmas.
Externí odkaz:
https://doaj.org/article/ed99a3d89b4343beb0ebcb8680884099
Autor:
Pilar Mendoza, Frauke Muecksch, Katrina G. Millard, Melissa Cipolla, Fengwen Zhang, Victor A. Ramos, Paul D. Bieniasz, Juan Dizon, Justin DaSilva, Alice Cho, Michel C. Nussenzweig, Shlomo Finkin, Mila Jankovic, Martina Turroja, Thiago Y. Oliveria, Fabian Schmidt, Zijun Wang, Marina Caskey, Theodora Hatziioannou, Anna Gazumyan, Irina Shimeliovich, Eva Bednarski, Marianna Agudelo, Christian Gaebler, Mridushi Daga, Dennis Schaefer-Babajew, Tarek Ben Tanfous
Publikováno v:
Nature
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection produces B cell responses that continue to evolve for at least a year. During that time, memory B cells express increasingly broad and potent antibodies that are resistant to muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add0e6c5f5a9c8e524e869b5473516a9
http://europepmc.org/articles/PMC8674133
http://europepmc.org/articles/PMC8674133
Autor:
Jianliang Xu, Robert A. Colbert, Martina Turroja, Fabian Schmidt, Jenna Ariel Lieberman, Roshni Patel, Yiska Weisblum, Justin Da Silva, Irina Shimeliovich, Kathryn E. Huey-Tubman, Zijun Wang, Marina Caskey, Thiago Y. Oliveira, Theodora Hatziioannou, Michel C. Nussenzweig, Cecille Unson-O'Brien, Morgan E. Abernathy, Christian Gaebler, Arlene Hurley, Melissa Cipolla, Rafael Casellas, Zhi Yang, Frauke Muecksch, Juan Dizon, Christopher O. Barnes, Kamille A. West, Anna Gazumyan, Katrina G. Millard, Shlomo Finkin, Victor A. Ramos, Paul D. Bieniasz, Pamela J. Bjorkman, Dennis Schaefer-Babajew, Kristie Gordon
Publikováno v:
bioRxiv
Signal Transduction and Targeted Therapy
Nature
Signal Transduction and Targeted Therapy
Nature
To date severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected over 100 million individuals resulting in over two million deaths. Many vaccines are being deployed to prevent coronavirus disease 2019 (COVID-19) including two novel m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afdccbb2e04218d82b6e8fac7d072289
https://doi.org/10.1038/s41586-021-03324-6
https://doi.org/10.1038/s41586-021-03324-6
Autor:
Paul Dominic B. Olinares, Melissa Cipolla, Michel C. Nussenzweig, Wenzhu Zhang, Julia Merkenschlager, Brian T. Chait, Anna Gazumyan, Thiago Y. Oliveira, Shlomo Finkin, Julian Kraft, Carla R. Nowosad, Harald Hartweger, Victor A. Ramos
Publikováno v:
Nature. 591:458-463
The germinal centre is a dynamic microenvironment in which B cells that express high-affinity antibody variants produced by somatic hypermutation are selected for clonal expansion by limiting the numbers of T follicular helper cells1,2. Although much
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::786568777bdfef196dde4e2b9450d36c
https://doi.org/10.1038/s41586-021-03187-x
https://doi.org/10.1038/s41586-021-03187-x
Autor:
Dennis Schaefer-Babajew, Frauke Muecksch, Mridushi Daga, Justin DaSilva, Mila Jankovic, Melissa Cipolla, Anna Gazumyan, Thiago Y. Oliveria, Martina Turroja, Marianna Agudelo, Tarek Ben Tanfous, Eva Bednarski, Pilar Mendoza, Katrina G. Millard, Michel C. Nussenzweig, Juan Dizon, Fengwen Zhang, Victor A. Ramos, Paul D. Bieniasz, Alice Cho, Shlomo Finkin, Fabian Schmidt, Zijun Wang, Marina Caskey, Irina Shimeliovich, Christian Gaebler, Theodora Hatziioannou
SummarySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection produces B-cell responses that continue to evolve for at least one year. During that time, memory B cells express increasingly broad and potent antibodies that are resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b92c22ef7b933dddd252d0ee64823a6d
https://doi.org/10.1101/2021.07.29.454333
https://doi.org/10.1101/2021.07.29.454333
Autor:
Frauke Muecksch, Charlotte Viant, Thiago Y. Oliveira, Theodora Hatziioannou, Eva Bednarski, Charles M. Rice, Hans Heinrich Hoffmann, Anna Gazumyan, Justin Da Silva, Christian Gaebler, Christopher O. Barnes, Michel C. Nussenzweig, Melissa Cipolla, Shlomo Finkin, Katrina G. Millard, Lauren C. Aguado, Martina Turroja, Victor A. Ramos, Paul D. Bieniasz, Zhen Zhao, Fabian Schmidt, Mila Jankovic, Alice Cho, Jim Yee, Zijun Wang, Marina Caskey, Mridushi Daga, Dennis Schaefer-Babajew
Publikováno v:
Nature
More than one year after its inception, the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains difficult to control despite the availability of several working vaccines. Progres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82b2b6bf9bd8f9fcf7226ca754bc2a7
https://resolver.caltech.edu/CaltechAUTHORS:20210510-104403619
https://resolver.caltech.edu/CaltechAUTHORS:20210510-104403619
Autor:
Frauke Muecksch, Charlotte Viant, Michel C. Nussenzweig, Thiago Y. Oliveira, Melissa Cipolla, Charles M. Rice, Martina Turroja, Zijun Wang, Marina Caskey, Mila Jankovic, Victor A. Ramos, Paul D. Bieniasz, Lauren C. Aguado, Eva Bednarski, Alice Cho, Shlomo Finkin, Zhen Zhao, Anna Gazumyan, Christopher O. Barnes, Katrina G. Millard, Fabian Schmidt, Christian Gaebler, Hans-Heinrich Hoffmann, Jim Yee, Mridushi Daga, Theodora Hatziioannou, Justin Da Silva, Dennis Schaefer-Babajew
Publikováno v:
bioRxiv
Over one year after its inception, the coronavirus disease-2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) remains difficult to control despite the availability of several excellent vaccines. Progress i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e202a2ed9da16fbbf2fc0b160dcd0740
https://doi.org/10.1101/2021.05.07.443175
https://doi.org/10.1101/2021.05.07.443175
Autor:
Fabian Schmidt, Thiago Y. Oliveira, Melissa Cipolla, Saurabh Mehandru, Yaron Bram, Minami Tokuyama, Pamela J. Bjorkman, Juan Dizon, Kristie Gordon, Michel C. Nussenzweig, Frauke Muecksch, Divya Jha, Zhen Zhao, Christopher O. Barnes, Pilar Mendoza, Charlotte Viant, Katrina G. Millard, Roshni Patel, Mila Jankovic, Martina Turroja, Irina Shimeliovich, Davide F. Robbiani, Arlene Hurley, Christian Gaebler, Julio C. C. Lorenzi, Thomas Hagglof, Cecille Unson-O'Brien, Jim Yee, Anna Gazumyan, Victor A. Ramos, Paul D. Bieniasz, Theodora Hatziioannou, Yiska Weisblum, Dennis Schaefer-Babajew, Michael Tankelevich, Zijun Wang, Marina Caskey, Robert E. Schwartz, Shlomo Finkin, Gustavo Martinez-Delgado, Alice Cho, Gaëlle Breton
Publikováno v:
Nature
bioRxiv
bioRxiv
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected 78 million individuals and is responsible for over 1.7 million deaths to date. Infection is associated with the development of variable levels of antibodies with neutralizing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdd69dab2b470dd9f528399fd731c2b
https://resolver.caltech.edu/CaltechAUTHORS:20201105-121857214
https://resolver.caltech.edu/CaltechAUTHORS:20201105-121857214
Autor:
Yiska Weisblum, Christopher O. Barnes, Fabian Schmidt, Davide F. Robbiani, Allison J. Greaney, Marianna Agudelo, Tyler N. Starr, Jesse D. Bloom, Zijun Wang, Marina Caskey, Frauke Muecksch, Shlomo Finkin, Daniel Poston, Paul D. Bieniasz, Michel C. Nussenzweig, Theodora Hatziioannou, Christian Gaebler, Pamela J. Bjorkman
Publikováno v:
Nature Communications
Monoclonal antibodies targeting a variety of epitopes have been isolated from individuals previously infected with SARS-CoV-2, but the relative contributions of these different antibody classes to the polyclonal response remains unclear. Here we use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e838e15e9cc9381883aa43b2498be99
https://doi.org/10.1101/2021.03.17.435863
https://doi.org/10.1101/2021.03.17.435863
Autor:
Kathryn E. Huey-Tubman, Andrew I. Flyak, Magdalena Rutkowska, Thiago Y. Oliveira, Anna Gazumyan, Zijun Wang, Marina Caskey, Celia A. Schiffer, Yiska Weisblum, Julio C. C. Lorenzi, Christian Gaebler, Shlomo Finkin, Victor A. Ramos, Paul D. Bieniasz, Frauke Muecksch, Michel C. Nussenzweig, Pamela J. Bjorkman, Fabian Schmidt, Dennis Schaefer-Babajew, Alice Cho, Christopher O. Barnes, Katrina G. Millard, Melissa Cipolla, Theodora Hatziioannou, Justin Da Silva, Daniel Poston, Andrew T. DeLaitsch, Shurong Hou
Publikováno v:
Immunity
Antibodies elicited by infection accumulate somatic mutations in germinal centers that can increase affinity for cognate antigens. We analyzed 6 independent groups of clonally related severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) Spike
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb5ac12380ac501fc4c33d534317220
https://doi.org/10.1101/2021.03.07.434227
https://doi.org/10.1101/2021.03.07.434227