Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shlomit Farkash-Amar"'
Autor:
Arigela Harikumar, Raghu Ram Edupuganti, Matan Sorek, Gajendra Kumar Azad, Styliani Markoulaki, Petra Sehnalová, Soňa Legartová, Eva Bártová, Shlomit Farkash-Amar, Rudolf Jaenisch, Uri Alon, Eran Meshorer
Publikováno v:
Stem Cell Reports, Vol 9, Iss 4, Pp 1304-1314 (2017)
Embryonic stem cells (ESCs), with their dual capacity to self-renew and differentiate, are commonly used to study differentiation, epigenetic regulation, lineage choices, and more. Using non-directed retroviral integration of a YFP/Cherry exon into m
Externí odkaz:
https://doaj.org/article/d8c7170f17f64996acc876ed0d2be165
Autor:
Shlomit Farkash-Amar, Anat Zimmer, Eran Eden, Ariel Cohen, Naama Geva-Zatorsky, Lydia Cohen, Ron Milo, Alex Sigal, Tamar Danon, Uri Alon
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004176 (2014)
To understand gene function, genetic analysis uses large perturbations such as gene deletion, knockdown or over-expression. Large perturbations have drawbacks: they move the cell far from its normal working point, and can thus be masked by off-target
Externí odkaz:
https://doaj.org/article/4950cfc9b8154f5498b93504f18a03e5
Autor:
Shlomit Farkash-Amar, Yaara David, Andreas Polten, Hadas Hezroni, Yonina C Eldar, Eran Meshorer, Zohar Yakhini, Itamar Simon
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48986 (2012)
DNA replication is a highly regulated process, with each genomic locus replicating at a distinct time of replication (ToR). Advances in ToR measurement technology enabled several genome-wide profiling studies that revealed tight associations between
Externí odkaz:
https://doaj.org/article/ceaca1d048a74b6e9fd937a34df80cbf
Autor:
Shlomit Farkash-Amar, Eran Eden, Ariel Cohen, Naama Geva-Zatorsky, Lydia Cohen, Ron Milo, Alex Sigal, Tamar Danon, Uri Alon
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48722 (2012)
Regulation of proteins across the cell cycle is a basic process in cell biology. It has been difficult to study this globally in human cells due to lack of methods to accurately follow protein levels and localizations over time. Estimates based on gl
Externí odkaz:
https://doaj.org/article/63af391b5a284426941e9d5fda367b5c
Publikováno v:
PLoS Genetics, Vol 6, Iss 7, p e1001011 (2010)
Recent evidence suggests that the timing of DNA replication is coordinated across megabase-scale domains in metazoan genomes, yet the importance of this aspect of genome organization is unclear. Here we show that replication timing is remarkably cons
Externí odkaz:
https://doaj.org/article/7b06755c4d644c318cebfb8a52be0f07
Autor:
Shlomit Farkash-Amar, Itamar Simon
Publikováno v:
Chromosome Research. 18:115-125
Microarray technology has facilitated the research of eukaryotic DNA replication on a genome-wide scale. Recent studies have shed light on the association between time of replication and chromosome structure, on the organization principles of the rep
Autor:
Zohar Yakhini, Andreas Polten, Shlomit Farkash-Amar, Yaara David, Hadas Hezroni, Yonina C. Eldar, Itamar Simon, Eran Meshorer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 11, p e48986 (2012)
PLoS ONE, Vol 7, Iss 11, p e48986 (2012)
DNA replication is a highly regulated process, with each genomic locus replicating at a distinct time of replication (ToR). Advances in ToR measurement technology enabled several genome-wide profiling studies that revealed tight associations between
Publikováno v:
PLoS Genetics, Vol 6, Iss 7, p e1001011 (2010)
PLoS Genetics
PLoS Genetics
Recent evidence suggests that the timing of DNA replication is coordinated across megabase-scale domains in metazoan genomes, yet the importance of this aspect of genome organization is unclear. Here we show that replication timing is remarkably cons
Autor:
Guy Zinman, Ariel Gispan, Shlomit Farkash-Amar, Giora Simchen, Michael Klutstein, Itamar Simon, Ziv Bar-Joseph, Zahava Siegfried
Publikováno v:
BMC Genomics
BMC Genomics, Vol 11, Iss 1, p 478 (2010)
BMC Genomics, Vol 11, Iss 1, p 478 (2010)
Background Regulation of meiosis and sporulation in Saccharomyces cerevisiae is a model for a highly regulated developmental process. Meiosis middle phase transcriptional regulation is governed by two transcription factors: the activator Ndt80 and th
Autor:
Shlomit Farkash-Amar, Charles Helmstetter, Andreas Polten, Alon Goren, Doron Lipson, Zohar Yakhini, Itamar Simon
The division of genomes into distinct replication time zones has long been established. However, an in-depth understanding of their organization and their relationship to transcription is incomplete. Taking advantage of a novel synchronization method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7538c2183f906c9a3dbb2aa45d2ea3c1
https://europepmc.org/articles/PMC2556267/
https://europepmc.org/articles/PMC2556267/