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pro vyhledávání: '"Shleshma Dhakal"'
Autor:
Amanda J Audesse, Shleshma Dhakal, Lexi-Amber Hassell, Zachary Gardell, Yuliya Nemtsova, Ashley E Webb
Publikováno v:
PLoS Genetics, Vol 15, Iss 4, p e1008097 (2019)
Maintenance of a healthy proteome is essential for cellular homeostasis and loss of proteostasis is associated with tissue dysfunction and neurodegenerative disease. The mechanisms that support proteostasis in healthy cells and how they become defect
Externí odkaz:
https://doaj.org/article/fc3e45a40a744edcad46e21a8f4a8f5e
Autor:
Anna Sloutskin, Shleshma Dhakal, Mitchell Yeary, Ashley E. Webb, Sun Y. Maybury-Lewis, Tamar Juven-Gershon, Abigail K. Brown
Publikováno v:
Aging Cell
Neural stem cells (NSCs) in the adult and aged brain are largely quiescent, and require transcriptional reprogramming to re‐enter the cell cycle. However, the mechanisms underlying these changes and how they are altered with age remain undefined. H
Autor:
Yuliya Nemtsova, Lexi-Amber Hassell, Ashley E. Webb, Shleshma Dhakal, Amanda J Audesse, Zachary Gardell
Publikováno v:
PLoS Genetics, Vol 15, Iss 4, p e1008097 (2019)
PLoS Genetics
PLoS Genetics
Maintenance of a healthy proteome is essential for cellular homeostasis and loss of proteostasis is associated with tissue dysfunction and neurodegenerative disease. The mechanisms that support proteostasis in healthy cells and how they become defect
Autor:
Yanjie Sun, Thomas Wisniewski, Eileen Do, Pankaj Mehta, Shleshma Dhakal, Henrieta Scholtzova, Shan Liu
Alzheimer's disease (AD) is characterized by the presence of parenchymal amyloid-β (Aβ) plaques, cerebral amyloid angiopathy (CAA) and neurofibrillary tangles. Currently there are no effective treatments for AD. Immunotherapeutic approaches under d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f61608d04882006cdd8551d0bd328c5
https://europepmc.org/articles/PMC5296786/
https://europepmc.org/articles/PMC5296786/