Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Shizuyo Honda"'
Autor:
Shinichi Kohsaka, Hidenori Wada, Takae Hirasawa, Yumiko Ondo, Shizuyo Honda, Eri Suzuki, Yasuko Nakamura, Takayoshi Uchiyama, Shigeo Uchino, Moe Tsutsumi
Publikováno v:
Journal of Neurochemistry. 97:1203-1214
A class of scaffolding protein containing the post-synaptic density-95/Dlg/ZO-1 (PDZ) domain is thought to be involved in synaptic trafficking of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors during development. To clarif
Autor:
Shizuyo Honda, Shinichi Kohsaka, Yasuko Nakamura, Shigeo Uchino, Shigeki Yanai, Yumiko Ondo, Hidenori Wada, Takae Hirasawa
Publikováno v:
Biochemical and Biophysical Research Communications. 310:1140-1147
Slo2 channels are a type of sodium-activated K+ channels and possess a typical PDZ binding motif at the carboxy-terminal end. Thus, we investigated whether Slo2 channels bind to PSD-95, because it is well known that other types of K+ channels, voltag
Autor:
Kazuyuki Nakajima, Yasuko Nakamura, Akihiko Kikuchi, Fernando López-Redondo, Masayuki Yamato, Shinichi Kohsaka, Shizuyo Honda, Teruo Okano
Publikováno v:
Biomaterials. 22:1213-1223
Because spontaneous host regeneration of damaged tissues is limited, novel therapeutics utilizing cultured cells with the aid of tissue engineering methods are promising alternatives for tissue replacement. One critical shortcoming is current require
Publikováno v:
Glia. 32:226-233
As described previously, a relatively high dose of neurotrophins increased the release of urokinase-type plasminogen activator (uPA) from cultured microglia. This biological response is suggested to be caused by ceramide, which is a metabolite of ner
Publikováno v:
Molecular Brain Research. 76:429-435
Glutamate transporters play an important role in the re-uptake of glutamate after its release from glutamatergic synapses. So far five of such transporters subtypes have been cloned from rodent and human brains. The densities of glutamate transporter
Publikováno v:
Neuroscience Letters. 275:203-206
The neurotrophic effect of glial cell line-derived neurotrophic factor (GDNF) has been well documented in both the central and peripheral nervous systems. From the histological findings, target cells of GDNF have been considered to be neurons. In the
Autor:
Kazuyuki Nakajima, Yoshiaki Kikuchi, Masahiro Ishikawa, Shinichi Kohsaka, Shizuyo Honda, Etsuko Ikoma, Yongmao Liu
Publikováno v:
Glia. 24:272-289
Although the physiological role of neurotrophins in neuronal development and survival has been extensively investigated, their role in glial cell physiology remains to be elucidated. In the present study, we investigated the effects of neurotrophins
Autor:
Yoshinori Imai, Kazuhide Inoue, Yo Sasaki, Shinichi Kohsaka, Keiko Ohsawa, Shizuyo Honda, Yasuko Nakamura
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 21(6)
The initial microglial responses that occur after brain injury and in various neurological diseases are characterized by microglial accumulation in the affected sites of brain that results from the migration and proliferation of these cells. The earl
Plasminogen enhances the secretion of plasminogen activator inhibitor-1 from cultured rat astrocytes
Publikováno v:
Neuroscience letters. 282(3)
To investigate the physiological significance of microglia-derived plasminogen (PGn) in the central nervous system, we determined the effects of rat PGn on the secretion of plasminogen activator inhibitor (PAI) in cultured rat astrocytes by reverse z
Publikováno v:
Neuroscience Research. 31:S39