Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Shizuo Odashima"'
Autor:
Kozue Miyauchi, Hiroyuki Kohno, Koretaro Takahashi, Satoshi Wanezaki, Jun Kawabata, Shizuo Odashima, Hideyuki Kurihara, Masashi Hosokawa
Publikováno v:
Food Science and Technology Research. 5(3):243-246
Note
The apoptosis-inducing effect of fucoxanthin on human leukemic HL-60 cells was investigated. Fucoxanthin, which was obtained from the brown alga Undaria pinnatifida, inhibited the proliferation of HL-60 cells and induced DNA fragmentation o
The apoptosis-inducing effect of fucoxanthin on human leukemic HL-60 cells was investigated. Fucoxanthin, which was obtained from the brown alga Undaria pinnatifida, inhibited the proliferation of HL-60 cells and induced DNA fragmentation o
Autor:
Akira Hara, Shizuo Odashima, Kumiko Satoh, Hajime Ohigashi, Wataru Kuki, Hideki Mori, Takuji Tanaka, Hiroshi Yonei, Masayo Maeda, Kunihiro Kawabata, Yasuo Takahashi, Koichi Koshimizu, Akira Murakami, Takahide Ota, Mikio Kakumoto, Kengo Matsunaga
Publikováno v:
Carcinogenesis. 19:425-431
The modifying effects of citrus auraptene given during the initiation and post-initiation phases of oral carcinogenesis initiated with 4-nitroquinoline 1-oxide (4-NQO) were investigated in male F344 rats. At 6 weeks of age, animals were divided into
Autor:
Hiroyuki Kohno, Koretaro Takahashi, Hideyuki Kurihara, Masashi Hosokawa, Kaoru Tochizawa, Shizuo Odashima
Publikováno v:
日本油化学会誌. 46(4):383-390
Effects of docosahexaenoic acid (DHA)-containing phospholipids (DHA-PLs) on retionic acid (RA)-induced cell differentiation and growth inhibition of the human promyelocytic leukemia cell line, HL-60 were investigated. Cell differentiation judged from
Autor:
Morimasa Wada, Shun'ichiro Taniguchi, Masayo Maeda, Nobuyuki Yamagishi, Shizuo Odashima, Takahide Ota, Motoharu Seiki, Masaaki Tatsuka
Publikováno v:
International Journal of Cancer. 71:88-93
A clonal cell line, 1-1ras1000, transformed by the activated c-Ha-ras oncogene, does not form metastases after i.v. injection into mice (experimental metastasis assay). Here, we show that this cell line is useful as a recipient to detect metastasis-i
Publikováno v:
Cancer Letters. 110:201-205
Fetal bovine serum (FBS) supplemented to the culture medium inhibited the metastasis of B16BL6 melanoma cells in a dose-dependent manner. This metastasis-inhibiting activity was accompanied by growth-promoting activity, up to the concentration of 10%
Publikováno v:
Life Sciences. 60:PL39-PL44
Ginsenoside Rh2, a plant glycoside with a dammarane skeleton resembling a steroid skeleton as an aglycone, has anticancer potentials in vitro or in vivo. To elucidate the molecular mechanisms of the effects of Rh2, we have examined the Cyclin-depende
Autor:
Masaaki Tatsuka, Morimasa Wada, Hiromi Mitsui, Shizuo Odashima, Yasunari Kashihara, Takahide Ota, Naoki Matsuda, Nobuyuki Yamagishi, Motoharu Seiki
Publikováno v:
Molecular Carcinogenesis. 15:300-308
The metastatic phenotype of tumor cells is thought to be induced by an aberrant signaling cascade or cascades that are different from those required for tumorigenicity. Oncogene-transfected cells with different tumorigenicities and metastatic potenti
Autor:
Kouhei Teraoka, Shizuo Odashima, Hiroko Yamagishi, Mikio Tanino, Zhi-ping Zong, Kohzaburo Fujikawa-Yamamoto
Publikováno v:
Biochemical and Biophysical Research Communications. 219:480-485
Saikosaponin (SS) b2 was found to inhibit the proliferation of B16 melanoma cells. To explore this mechanism, we employed flow cytometry to determine the distribution of DNA content. The cell cycle of B16 melanoma cells was accumulated in the G1 phas
Autor:
Zhi-ping Zong, Kohzaburo Fujikawa-Yamamoto, Kouhei Teraoka, Shizuo Odashima, Hiroko Yamagishi
Publikováno v:
Cell Structure and Function. 19:391-396
Demecolcine (Colcemid), an inhibitor of spindle fiber formation in M phase, induced apoptosis in V79 cells. At a concentration of 0.01 microgram/ml demecolcine, V79 cells proliferated exponentially as well as controls, although temporal M phase accum
Autor:
Shizuo Odashima, Hiroaki Ohshima, Hiroyuki Kohno, Koretaro Takahashi, Mutuo Hatano, Masashi Hosokawa
Publikováno v:
NIPPON SUISAN GAKKAISHI. 59:309-314
Phosphatidylcholine containing highly unsaturated fatty acid (HUFA-PC) was prepared by porcine pancreatic phospholipase A2, which catalyzed esterification between lysophosphatidylcholine (LPC) and highly unsaturated fatty acid (HUFA), under a scaled-