Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Shizuo HASEGAWA"'
Publikováno v:
Food and Nutrition Sciences. :1547-1552
Dietary fiber is a non-digestible carbohydrate providing beneficial effects for bowel health. The aim of this study was to evaluate the clinical effects of fiber supplementation in enteral feeding on elderly patients suffering from diarrhea. This stu
Publikováno v:
Respiratory Medicine. 94:542-548
To improve patients' quality of life and decrease pollution risks to medical personnel, we tested the usefulness of a nitric oxide (NO) inhalation system consisting of a nasal cannula and a demand valve in an open circuit system. To estimate the cont
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 11:281-285
The mechanism of relaxation of the guinea-pig trachea induced by pituitary adenylate cyclase activating peptide (PACAP)-27 was investigated. We examined whether modulators of nitric oxide (NO) and carbon monoxide (CO) affect PACAP-induced response of
Autor:
Akihiro Nomura, Yukio Ishii, Shizuo Hasegawa, Tohru Sakamoto, Yoshiyuki Uchida, Manabu Shirato, Hiroaki Iijima, Yukio Goto
Publikováno v:
Biochemical Journal. 333:795-799
We have isolated a full-length cDNA for an inducible nitric oxide synthase (iNOS) from guinea-pig lung. The cDNA has a 3447 bp open reading frame encoding 1149 amino acid residues. The deduced amino acid sequence is approx. 80% identical with iNOS of
Autor:
Hiroaki Iijima, Shizuo Hasegawa, Takeo Endo, Anbo Xiang, Manabu Shirato, Akihiro Nomura, Yoshiyuki Uchida
Publikováno v:
British Journal of Pharmacology. 124:1019-1028
1 Endogenous nitric oxide (NO) can be detected in exhaled air and accumulates in inflamed airways. However its physiological role has not been fully elucidated. In this study, we investigated a role for endogenous NO in allergen-induced airway respon
Autor:
Hiroki Ninomiya, Itaru Ohtsu, Toshiyuki Ishimitsu, Michiko Sakane, Iwao Yamaguchi, Yasuro Sugishita, Toshihiko Saito, Shizuo Hasegawa
Publikováno v:
Japanese Circulation Journal. 62:877-882
The objective of this study was to investigate the effects of inhaled nitric oxide (NO) on chronic pulmonary hypertension (PH). Thirty patients with valvular heart diseases (n=8, group A), chronic lung diseases (n=16, group B), primary PH or PH due t
Autor:
Shizuo Hasegawa, Hideto Takahashi, Hiroshi Kamma, Hiroichi Ishikawa, Morio Ohtsuka, Hiroaki Satoh, Yuko T. Yamashita
Publikováno v:
Respiration. 65:295-298
To evaluate the relationship between serum levels of sialyl Lewis X-i antigen and lung metastasis in patients with non-small cell lung cancer (NSCLC), we measured the serum level of the antigen in 299 patients with untreated locally advanced or metas
Autor:
Shizuo Hasegawa
Publikováno v:
Nihon Naika Gakkai Zasshi. 87:519-523
Autor:
Shizuo Hasegawa, Hui Yang, Fusao Hirata, Tohru Sakamoto, Akihiro Nomura, David J. P. Bassett, Yukio Ishii
Publikováno v:
Toxicology and Applied Pharmacology. 147:214-223
The alveolar macrophage generation of interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) cytokines has been implicated in the recruitment of neutrophils into acutely injured lungs. To examine the role of these cytokines in neu
Autor:
Hideyuki Yokote, Shizuo Hasegawa, Taisuke Nomoto, Kazuto Nishio, Nagahiro Saijo, Hitoshi Arioka, Hisao Fukumoto, Kazuya Fukuoka, Hirokazu Kurokawa, Tomoyuki Ishida
Publikováno v:
International Journal of Cancer. 72:865-870
A novel antitumor antibiotic 7-N-[2-[[2-(g-L-glutamylamino)ethyl]dithio]ethyl] mitomycin C (KW-2149), an analogue of mitomycin C (MMC), is activated by thiol molecules, such as glutathione (GSH). To clarify the relationship between cellular GSH level