Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Shizuko KOBAYASHI"'
Autor:
Yuko Higaki, Miki Izumi, Kyoko Nomura, Junji Otaki, Shizuko Kobayashi, Takayuki Komoda, Masayasu Seki, Yu Akaishi
Publikováno v:
The Tohoku Journal of Experimental Medicine. 229:233-237
The shortage of physicians has become a serious problem in Japan. It has been pointed out that an increase in the number of female doctors may contribute to the aggravation of this shortage because it is known that women work fewer hours than male do
Autor:
Shizuko Kobayashi
Publikováno v:
YAKUGAKU ZASSHI. 126:677-693
Ultraviolet radiation is the major environmental cause of skin damage. Although only 0.5% of ultraviolet B (UVB) radiation reaches the earth, it is the main cause of sunburn and inflammation and the most carcinogenic constituent of sunlight. We inves
Autor:
Emiko Yoshida, Jiro Takata, Tatsuya Watanabe, Akihiko Yamazaki, Yoshiharu Karube, Shizuko Kobayashi
Publikováno v:
Journal of Investigative Dermatology. 126(7):1633-1640
We previously demonstrated that a novel hydrophilic gamma-tocopherol (gamma-Toc) derivative, gamma-tocopherol-N,N-dimethylglycinate hydrochloride (gamma-TDMG) converts to gamma-Toc in the mouse skin and has a higher bioavailability than gamma-Toc its
Autor:
SHIZUKO KOBAYASHI
Publikováno v:
Nihon Nyugan Kenshin Gakkaishi (Journal of Japan Association of Breast Cancer Screening). 15:69-74
Publikováno v:
Journal of Health Science. 51:734-737
The Shumiya cataract rat (SCR) is a hereditary cataract model in which lens opacity appears spontaneously in both the nuclear and perinuclear regions of 10‐11 week old animals. The expression of drug metabolizing enzymes, including cytochrome P450
Publikováno v:
BUNSEKI KAGAKU. 54:775-782
畜水産物に使用される動物用医薬品は,生産性の向上や疾病予防や治療のため使用量が増大し,その残留の可能性が懸念されている.一方,食品の安全性確保のため公布された「ポジテ
Publikováno v:
Journal of Health Science. 51:122-129
The quenching abilities of sodium L-ascorbyl-2-phosphate (APS) and ascorbic acid 2-glucose (AG) against UVB/A-generated free radicals in cultured mouse skin were investigated using electron spin resonance (ESR). The relation between their quenching a
Autor:
Shizuko Kobayashi, Hiroshi Suzuki, Atsushi Shibata, Hitoshi Nakagama, Mitsuko Masutani, Takashi Sugimura, Hirobumi Teraoka, Kenichi Masumura, Nobuo Kamada, Takehiko Nohmi
Publikováno v:
Oncogene. 24:1328-1337
Accumulated evidence suggests that Parp-1 is involved in DNA repair processes, including base excision repair, single-strand and double-strand break repairs. To understand the precise role of Parp-1 in genomic stability in vivo, we carried out mutati
Autor:
Satoki Ueno, Mikako Oka, Shizuko Kobayashi, Makoto Takehana, Noriyasu Hada, Yumiko Aoyama, Jun Inoue, Tadahiro Takeda
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 20:1-13
We studied the intraocular pharmacokinetics of dorzolamide hydrochloride eye drops and the effect of dorzolamide on carbonic anhydrase activity and localization in ocular tissues. Carbonic anhydrase activity was detected in normal ocular tissues. The
Publikováno v:
Biochemical and Biophysical Research Communications. 313:263-270
Drosophila Crumbs and the mammalian homologues encoded by the Crb genes are transmembrane proteins required for determination of retinal cell polarity. We cloned a novel variant of mouse Crb1 and termed it Crb1s. Since the 3′-end of exon 6 remained