Výsledky vyhledávání - "Shizuka Sakairi"

Vitamin K2 selectively induced apoptosis in ovarian TYK-nu and pancreatic MIA PaCa-2 cells out of eight solid tumor cell lines through a mechanism different from geranylgeraniol

Autor: Shizuka Sakairi, Toshiko Shibayama-Imazu, Shigeo Nakajo, Toshihiro Aiuchi, Akiko Watanabe, Kazuyasu Nakaya

Publikováno v: Journal of Cancer Research and Clinical Oncology. 129:1-11

Purpose. In this study, we examined the effects of vitamin K2 (menaquinone 4), which has a geranylgeranyl side chain, on various lines of cells derived from human solid tumors and compared them with the effects of geranylgeraniol (GGO). Methods. Cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ffdbf4d3bc0c4f19559612159d453f
https://doi.org/10.1007/s00432-002-0393-7

Zobrazit plný text záznamu

Production of superoxide and dissipation of mitochondrial transmembrane potential by vitamin K2 trigger apoptosis in human ovarian cancer TYK-nu cells

Autor: Hiroyuki Itabe, Shizuka Sakairi, Shigeo Nakajo, Toshihiro Aiuchi, Toshiko Shibayama-Imazu, Kazuyasu Nakaya, Wei-wei Ann, Ikuko Sonoda

Publikováno v: Apoptosis : an international journal on programmed cell death. 11(9)

We reported previously that vitamin K(2) selectively induces apoptosis in human ovary cancer cells (TYK-nu cells) and pancreatic cancer cells (MIA PaCa-2 cells) through a mitochondrion-dependent pathway. In the present study, we examined the details

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309ecc8e1b60ef6b129e62804cf7f4d6
https://pubmed.ncbi.nlm.nih.gov/16763728

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání