Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Shizuka Hirai"'
Publikováno v:
Heliyon, Vol 9, Iss 1, Pp e12743- (2023)
[Aims] Flavonoid apigenin (API) has a wide range of biological functions, particularly anti-inflammation. Indoleamine 2,3-dioxygenase (IDO) and 2-Amino-3-carboxymuconate-6-semialdehyde decarboxylase (ACMSD) are important tryptophan metabolic enzymes
Externí odkaz:
https://doaj.org/article/f5fa9d26af0147f3a8b3f12da9c45c37
Publikováno v:
Molecules, Vol 26, Iss 3, p 546 (2021)
Obesity is a major risk factor for some metabolic disorders including type 2 diabetes. Enhancement of peroxisome proliferator-activated receptor (PPAR) γ, a master regulator of adipocyte differentiation, is known to increase insulin-sensitive small
Externí odkaz:
https://doaj.org/article/7024db16545445f39100eb1780045be8
Autor:
Tsuyoshi Goto, Joo-Young Lee, Aki Teraminami, Yong-Il Kim, Shizuka Hirai, Taku Uemura, Hiroyasu Inoue, Nobuyuki Takahashi, Teruo Kawada
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 5, Pp 873-884 (2011)
Peroxisome proliferator-activated receptor-α (PPARα) is a dietary lipid sensor, whose activation results in hypolipidemic effects. In this study, we investigated whether PPARα activation affects energy metabolism in white adipose tissue (WAT). Act
Externí odkaz:
https://doaj.org/article/9c1dd005232c471789cdd0b1e4e0d917
Autor:
Young-il Kim, Shizuka Hirai, Tsuyoshi Goto, Chie Ohyane, Haruya Takahashi, Taneaki Tsugane, Chiaki Konishi, Takashi Fujii, Shuji Inai, Yoko Iijima, Koh Aoki, Daisuke Shibata, Nobuyuki Takahashi, Teruo Kawada
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31317 (2012)
Dyslipidemia is a major risk factor for development of several obesity-related diseases. The peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription factor that regulates energy metabolism. Previously, we reported t
Externí odkaz:
https://doaj.org/article/3e373e39d3b2419884ee164a13fa48db
Publikováno v:
PPAR Research, Vol 2010 (2010)
Several herbal plants improve medical conditions. Such plants contain many bioactive phytochemicals. Terpenoids (also called “isoprenoids”) constitute one of the largest families of natural products accounting for more than 40,000 individual comp
Externí odkaz:
https://doaj.org/article/5d80fc87b4584963bc936644ea50b11b
Autor:
Shizuka Hirai, Nobuyuki Takahashi, Tsuyoshi Goto, Shan Lin, Taku Uemura, Rina Yu, Teruo Kawada
Publikováno v:
Mediators of Inflammation, Vol 2010 (2010)
Obesity is associated with a low-grade systemic chronic inflammatory state, characterized by the abnormal production of pro- and anti-inflammatory adipocytokines. It has been found that immune cells such as macrophages can infiltrate adipose tissue a
Externí odkaz:
https://doaj.org/article/7422c911cbe846caa8bf1fd6633899ab
Autor:
Dian Kurniati, Ryohei Umeda, Natsuko Kagawa, Eiji Goto, Ryo Wakabayashi, Kanae Shimada, Shizuka Hirai, Yukari Egashira
Publikováno v:
Bioscience, biotechnology, and biochemistry. 86(7)
UV-irradiated red perilla demonstrated promising protective effects against carbon tetrachloride-induced liver injury in mice. UV exposure significantly enhanced the accumulation of rosmarinic acid, malonylshisonin and shisonin in red perilla, and in
Autor:
Mari Maeda-Yamamoto, Norihiro Kametani, Shizuka Hirai, Tomoko Kamohara, Yukari Egashira, Yuki Shinoda, Manami Koshiguchi
Publikováno v:
SC10202003030008
NARO成果DBa
NARO成果DBa
We investigated the combined effects of 'Benifuuki,' a tea cultivar that contains O-methylated catechins like epigallocatechin-3-O-(3-O-methyl) gallate, and quercetin on hepatic fat accumulation in male Sprague-Dawley rats fed a high-fat, high-choles
Autor:
Haruhisa Kikuchi, Daiki Nakahara, Koichiro Mori, Cui Nan, Yukari Egashira, Shizuka Hirai, Motoki Hanayama
Publikováno v:
European journal of nutritionReferences. 59(7)
Mushrooms are reported to have a variety of health-promoting activities. However, little information is available on the effects of intake of polysaccharides from Pleurotus eryngii on obesity. In this study, we investigated the effects of P. eryngii
Publikováno v:
Phytotherapy research : PTRREFERENCES. 34(6)
Osteoporosis is associated with increase in fat tissue in bone marrow in humans. Mesenchymal stem cells in bone marrow are induced to differentiate into osteoblasts rather than adipocytes by the stimulation of peroxisome proliferator-activated recept