Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shizuka Aritomi"'
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 749-759 (2024)
Introduction: Neural crest cells (NCCs) are cell populations that originate during the formation of neural crest in developmental stages. They are characterized by their multipotency, self-renewal and migration potential. Given their ability to diffe
Externí odkaz:
https://doaj.org/article/532571a6926e45ea9b4488c6b4d6fa41
Autor:
Denise Zujur, Ziadoon Al-Akashi, Anna Nakamura, Chengzhu Zhao, Kazuma Takahashi, Shizuka Aritomi, William Theoputra, Daisuke Kamiya, Koichi Nakayama, Makoto Ikeya
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: To date, there is no effective long-lasting treatment for cartilage tissue repair. Primary chondrocytes and mesenchymal stem/stromal cells are the most commonly used cell sources in regenerative medicine. However, both cell types have lim
Externí odkaz:
https://doaj.org/article/e0af63184c45470983c411e103e08cd7
Autor:
Akira Takahara, Hirotaka Wagatsuma, Shizuka Aritomi, Tomoyuki Konda, Yasuki Akie, Yuji Nakamura, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 116, Iss 1, Pp 132-135 (2011)
Abstract.: The chronic atrioventricular block (CAVB) dog has been widely used as an in vivo proarrhythmia model. mRNA levels of K+ and Ca2+ channels in the isolated ventricular tissues from normal and CAVB dogs were assayed using a real-time PCR. The
Externí odkaz:
https://doaj.org/article/65dac53524854aa7bd120c6b8212c0e8
Publikováno v:
Clinical and Experimental Pharmacology & Physiology
Cilnidipine is an L/N-type calcium channel blocker (CCB). The effects of cilnidipine on N-type channels give it unique organ-protective properties via the suppression of hyperactivity in the sympathetic nervous system (SNS) and renin-angiotensin-aldo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1deb1a35ea9f59870bc41de3ab724740
https://doi.org/10.1111/1440-1681.12360
https://doi.org/10.1111/1440-1681.12360
Autor:
Caroline Sunggip, Shota Saiki, Shizuka Aritomi, Katsuya Hirano, Tatsuya Ishikawa, Motohiro Nishida, Koichiro Kuwahara, Yasuo Mori, Shokei Kim-Mitsuyama, Eri Harada
Publikováno v:
Biochemical and Biophysical Research Communications. 434(2):210-216
N-type voltage-dependent Ca2+channels (VDCCs), expressed predominantly in the nervous system, play pivotal roles in sympathetic regulation of the circulatory system. Although N-type VDCCs are also reportedly expressed in the vasculature, their pathop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe03e71bcce0e87e516e20806cd89184
Autor:
Miki Kato, Hiromi Ito, Tamayo Murase, Miwa Takatsu, Toyoaki Murohara, Kohzo Nagata, Kazumi Niinuma, Takuya Hattori, Keiji Takahashi, Masafumi Ohtake, Shizuka Aritomi, Keigo Nashima, Chieko Nakashima
Publikováno v:
Journal of Hypertension. 30:1845-1855
OBJECTIVE The L/N-type calcium channel blocker (CCB) cilnidipine suppresses sympathetic nerve activity and has a superior renoprotective effect compared with L-type CCBs such as amlodipine. The cardioprotective action of cilnidipine has remained larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae64e1f05851a3b77d7645e9ee074d6
https://doi.org/10.1097/hjh.0b013e3283567645
https://doi.org/10.1097/hjh.0b013e3283567645
Publikováno v:
Heart and Vessels. 27:419-423
The L/N-type calcium channel blocker cilnidipine has been shown to suppress aldosterone production induced by angiotensin II (Ang II) in vitro. In addition, cilnidipine also suppresses the reflex tachycardia induced by its antihypertensive action in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d52c2f84f241a72b0f65a3eb26a2b0d
https://doi.org/10.1007/s00380-011-0191-8
https://doi.org/10.1007/s00380-011-0191-8
Publikováno v:
American Journal of Nephrology. 33:168-175
Background: Interrupting the renin-angiotensin system (RAS) with an angiotensin II receptor blocker (ARB) has been found to induce RAS overactivation. In this study, we investigated the effect of 2 calcium channel blockers (CCBs), cilnidipine (L-/N-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f4ae8a9ad3e4251f2a45555bac6693
https://doi.org/10.1159/000323969
https://doi.org/10.1159/000323969
Autor:
Yuji Nakamura, Tomoyuki Konda, Akira Takahara, Yasuki Akie, Hirotaka Wagatsuma, Shizuka Aritomi, Atsushi Sugiyama
Publikováno v:
Journal of Pharmacological Sciences, Vol 116, Iss 1, Pp 132-135 (2011)
The chronic atrioventricular block (CAVB) dog has been widely used as an in vivo proarrhythmia model. mRNA levels of K+ and Ca2+ channels in the isolated ventricular tissues from normal and CAVB dogs were assayed using a real-time PCR. The mRNA level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce2badd90ad3b08a1668409ad12d3eb
http://www.sciencedirect.com/science/article/pii/S1347861319307303
http://www.sciencedirect.com/science/article/pii/S1347861319307303
Autor:
Yasuki Akie, Shizuka Aritomi, Atsushi Sugiyama, Yoshioki Satoh, Yuji Nakamura, Hirotaka Wagatsuma, A Nakayama, Akira Takahara
Publikováno v:
British Journal of Pharmacology. 158:1366-1374
Background and purpose: The heart of the canine model of chronic atrioventricular block is known to have a ventricular electrical remodelling, which mimics the pathophysiology of long QT syndrome. Using this model, we explored a new pharmacological t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1817f706423ace99c69ba39de691a4c4
https://doi.org/10.1111/j.1476-5381.2009.00407.x
https://doi.org/10.1111/j.1476-5381.2009.00407.x