Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Shizou Akira"'
Autor:
Timothy Sheahan, Thomas E Morrison, William Funkhouser, Satoshi Uematsu, Shizou Akira, Ralph S Baric, Mark T Heise
Publikováno v:
PLoS Pathogens, Vol 4, Iss 12, p e1000240 (2008)
A novel human coronavirus, SARS-CoV, emerged suddenly in 2003, causing approximately 8000 human cases and more than 700 deaths worldwide. Since most animal models fail to faithfully recapitulate the clinical course of SARS-CoV in humans, the virus an
Externí odkaz:
https://doaj.org/article/a0cf73727fe144368a4f7fd3ac93e2d5
Autor:
John C. Reed, Tanenobu Harada, Tadaaki Miyazaki, Daisuke Fujikura, Hong Mei Li, Taro Kawai, Shizou Akira, Atsushi Iwai, Jun Uehara
Publikováno v:
Cell Death & Differentiation. 16:1615-1621
Detachment of adherent epithelial cells from the extracellular matrix induces apoptosis, a process known as anoikis. We have shown that DAP3 is critical for anoikis induction. However, the mechanism for anoikis induction mediated by DAP3 is still unc
Autor:
Dina C. Nacionales, Jun Akaogi, Pui Lee, Bryan R.G. Williams, Minoru Satoh, Kindra M. Kelly, Shizou Akira, Philip O. Scumpia, Masahiro Yamamoto, Robert Lyons, Westley H. Reeves, Haoyang Zhuang
Publikováno v:
Arthritis & Rheumatism. 54:1557-1567
Objective Most lupus patients produce autoantibodies against small ribonucleoproteins such as Sm/RNP and Ro 60 (containing U1 and Y1–Y5 RNAs, respectively). We undertook this study to investigate whether the RNA components of these antigens, which
Publikováno v:
International Congress Series. 1285:10-14
Individual Toll-like receptor (TLR) recognizes distinct components derived from pathogens, and triggers inflammatory and immune responses including production of cytokines and chemokines as well as activation of dendritic cells. TLR recruits IL-1 rec
Autor:
Andrea Schuessler, Robert H. Silverman, Helen M. Lazear, Stephane Daffis, Paul J. Hertzog, Daphne A. Cooper, Babal K. Jha, Alexander A. Khromykh, Shizou Akira, Osamu Takeuchi, David J. Barton, Yutaro Kumagai, Michael S. Diamond, Shessy Torres, Anneke Funk
Publikováno v:
Journal of virology. 86(10)
We previously showed that a noncoding subgenomic flavivirus RNA (sfRNA) is required for viral pathogenicity, as a mutant West Nile virus (WNV) deficient in sfRNA production replicated poorly in wild-type mice. To investigate the possible immunomodula
Autor:
Phillip I. Bird, Shizou Akira, Sally V. Watt, Desiree A Anthony, Melvyn T. Chow, Joseph A. Trapani, Mark J. Smyth, Daniel M. Andrews, Colin M. House
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 185(3)
Lymphocyte perforin and serine protease granzymes are well-recognized extrinsic mediators of apoptosis. We now demonstrate that cytotoxic lymphocyte granule components profoundly augment the myeloid cell inflammatory cytokine cascade in response to T
Autor:
Dragana Odobasic, Joshua D. Ooi, Shaun A. Summers, Oliver M. Steinmetz, Shizou Akira, Stephen R. Holdsworth, Kim M. O’Sullivan, Arthur R Kitching, Alberta Hoi
Publikováno v:
Journal of autoimmunity. 35(4)
Systemic lupus erythematosus is a common autoimmune disease, with kidney involvement a serious complication associated with poor prognosis. Humoral immune responses constitute the hallmark of disease, however T helper cells are required for the gener
Autor:
Kim, Jeongwon1 (AUTHOR), Ha, Sugyeong1 (AUTHOR), Son, Minjung1 (AUTHOR), Kim, Doyeon1 (AUTHOR), Kim, Mi-Jeong1 (AUTHOR), Kim, Bumseok2 (AUTHOR), Kim, Donghwan3 (AUTHOR), Chung, Hae Young1 (AUTHOR), Chung, Ki Wung1 (AUTHOR) kieungc@pusan.ac.kr
Publikováno v:
Cell Communication & Signaling. 8/18/2023, Vol. 21 Issue 1, p1-16. 16p.
Autor:
Hunt, Jonathan J.1 (AUTHOR), Astley, Roger2,3 (AUTHOR), Wheatley, Nanette2,3 (AUTHOR), Wang, Jin-Town4 (AUTHOR), Callegan, Michelle C.1,2,3 (AUTHOR) michelle-callegan@ouhsc.edu
Publikováno v:
Current Eye Research. Aug2014, Vol. 39 Issue 8, p790-802. 13p.
Autor:
Brickey, Willie J.1 (AUTHOR), Neuringer, Isabel P.2 (AUTHOR), Walton, William3 (AUTHOR), Hua, Xiaoyang2 (AUTHOR), Wang, Ellis Y.3 (AUTHOR), Jha, Sushmita3 (AUTHOR), Sempowski, Gregory D.4 (AUTHOR), Yang, Xuebin5 (AUTHOR), Kirby, Suzanne L.3,5 (AUTHOR), Tilley, Stephen L.2 (AUTHOR), Ting, Jenny P.-Y.1,3 (AUTHOR) jenny_ting@med.unc.edu
Publikováno v:
International Journal of Radiation Biology. Apr2012, Vol. 88 Issue 4, p335-347. 13p. 6 Graphs.