Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Shizhu Zhang"'
Publikováno v:
mSphere, Vol 9, Iss 5 (2024)
ABSTRACT Endocytosis has been extensively studied in yeasts, where it plays crucial roles in growth, signaling regulation, and cell-surface receptor internalization. However, the biological functions of endocytosis in pathogenic filamentous fungi rem
Externí odkaz:
https://doaj.org/article/56d9d1b5ac3142b0ad128971926a7f1c
Publikováno v:
npj Biofilms and Microbiomes, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract The filamentous fungus Aspergillus fumigatus is an ubiquitous mold that can cause invasive pulmonary infections in immunocompromised patients. Within the lung, A. fumigatus forms biofilms that can enhance resistance to antifungals and immune
Externí odkaz:
https://doaj.org/article/ff4c0885619c41afa65d8ea307718eea
Publikováno v:
Virulence, Vol 10, Iss 1, Pp 234-247 (2019)
Aspergillus fumigatus is the most prevalent airborne fungal pathogen that causes invasive fungal infections in immunosuppressed individuals. Adaptation to iron limited conditions is crucial for A. fumigatus virulence. To identify novel genes that pla
Externí odkaz:
https://doaj.org/article/cd16f6dbcbdd4d329f30cf5810c828f9
Autor:
Yuan Chen, Francois Le Mauff, Yan Wang, Ruiyang Lu, Donald C. Sheppard, Ling Lu, Shizhu Zhang
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT Polysaccharides are key components of both the fungal cell wall and biofilm matrix. Despite having distinct assembly and regulation pathways, matrix exopolysaccharide and cell wall polysaccharides share common substrates and intermediates in
Externí odkaz:
https://doaj.org/article/5defdb444c7b4839a856a4a1d4c16034
Publikováno v:
mSphere, Vol 5, Iss 5 (2020)
ABSTRACT The rise of drug resistance in fungal pathogens is becoming a serious problem owing to the limited number of antifungal drugs available. Identifying and targeting factors essential for virulence or development unique to fungal pathogens is o
Externí odkaz:
https://doaj.org/article/99ceb123ce674f7ca846d1a424639417
Publikováno v:
Journal of Fungi, Vol 7, Iss 11, p 920 (2021)
Transient Receptor Potential (TRP) proteins constitute a superfamily that encodes transmembrane ion channels with highly diverse permeation and gating properties. Filamentous fungi possess putative TRP channel-encoded genes, but their functions remai
Externí odkaz:
https://doaj.org/article/f5b7442a575d4bbc8173caad1efa25e1
Autor:
Nanbiao Long, Thomas Orasch, Shizhu Zhang, Lu Gao, Xiaoling Xu, Peter Hortschansky, Jing Ye, Fenli Zhang, Kai Xu, Fabio Gsaller, Maria Straßburger, Ulrike Binder, Thorsten Heinekamp, Axel A Brakhage, Hubertus Haas, Ling Lu
Publikováno v:
PLoS Genetics, Vol 14, Iss 10, p e1007762 (2018)
Both branched-chain amino acids (BCAA) and iron are essential nutrients for eukaryotic cells. Previously, the Zn2Cys6-type transcription factor Leu3/LeuB was shown to play a crucial role in regulation of BCAA biosynthesis and nitrogen metabolism in S
Externí odkaz:
https://doaj.org/article/be69d7fd105d4bbb84fc6f1c2324f420
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
The claudin family protein Fig1 is a unique fungal protein that is involved in pheromone-induced calcium influx and membrane fusion during the mating of Saccharomyces cerevisiae and Candida albicans. Whether and how Fig1 regulates Ca2+ homeostasis in
Externí odkaz:
https://doaj.org/article/3dd11f7f856e4567865a22c0f3886856
Autor:
Yuanwei Zhang, Qingqing Zheng, Congcong Sun, Jinxing Song, Lina Gao, Shizhu Zhang, Alberto Muñoz, Nick D Read, Ling Lu
Publikováno v:
PLoS Genetics, Vol 12, Iss 4, p e1005977 (2016)
Finely tuned changes in cytosolic free calcium ([Ca2+]c) mediate numerous intracellular functions resulting in the activation or inactivation of a series of target proteins. Palmitoylation is a reversible post-translational modification involved in m
Externí odkaz:
https://doaj.org/article/19cf1f746ff347b1bfb36875b8af1003
Publikováno v:
Polymers, Vol 10, Iss 5, p 492 (2018)
Hyperlipidemia is a key risk factor in inducing fatty liver, hypertension, atherosclerosis and cerebrovascular diseases. Previous studies have verified that polysaccharides from fruiting bodies (PEPE) of Pleurotus eryngii (king oyster mushroom) are c
Externí odkaz:
https://doaj.org/article/cffdbb0f834145d98a214a02b373f1ee