Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shizhen Qiu"'
Autor:
Ling He, Xiangjun Zhou, Jia Liu, Yina Yao, Junyuan Lin, Jialong Chen, Shizhen Qiu, Zeyu Liu, Yingzheng He, Yujie Yi, Xueqiong Zhou, Fei Zou
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 265, Iss , Pp 115513- (2023)
Abstractc: Esophageal cancer (EC) is the sixth cause of cancer-related deaths and still is a significant public health problem globally. Nitrosamines exposure represents a major health concern increasing EC risks. Exploring the mechanisms induced by
Externí odkaz:
https://doaj.org/article/f7b4640cddd646018470b691f2d01bb7
Autor:
Yuetong Wang, Fei Wang, Lihua Wang, Shizhen Qiu, Yufeng Yao, Chenxu Yan, Xuexue Xiong, Xuyong Chen, Quanquan Ji, Jian Cao, Ganglong Gao, Dake Li, Liye Zhang, Zhiqian Guo, Ruoning Wang, Haopeng Wang, Gaofeng Fan
Publikováno v:
Cell Reports, Vol 36, Iss 6, Pp 109516- (2021)
Summary: Although tumor-infiltrating lymphocytes (TILs) maintain their ability to proliferate, persist, and eradicate tumors, they are frequently dysfunctional in situ. By performing both whole-genome CRISPR and metabolic inhibitor screens, we identi
Externí odkaz:
https://doaj.org/article/4602e51883054ef38bd82cd29fcd42d3
Autor:
Jian Chen, Shizhen Qiu, Wentao Li, Kun Wang, Yu Zhang, Han Yang, Baichuan Liu, Guangfei Li, Li Li, Min Chen, Junjie Lan, Jiahua Niu, Peijie He, Lei Cheng, Gaofeng Fan, Xin Liu, Xianmin Song, Chenqi Xu, Haitao Wu, Haopeng Wang
Publikováno v:
Cell Research. 33:341-354
Tonic signaling of chimeric antigen receptor (CAR), i.e., the spontaneous CAR activation in the absence of tumor antigen stimulation, is considered to be a pivotal event controlling CAR-T efficacy. However, the molecular mechanism underlying the spon
Autor:
Simeng Zhao, Fengjiang Liu, Shizhen Qiu, Qiaoshuai Lan, Yiran Wu, Wei Xu, Junzi Ke, Jie Yang, Xiaoyan Liu, Kun Wang, Hangtian Guo, Shuai Xia, Fangfang Zhang, Jiabei Wang, Xiaowen Hu, Lu Lu, Shibo Jiang, Suwen Zhao, Lianxin Liu, Youhua Xie, Xiuna Yang, Haopeng Wang, Guisheng Zhong
Publikováno v:
Protein & Cell.
Autor:
Haopeng Wang, Yuetong Wang, Liye Zhang, Dake Li, Xuyong Chen, Xuexue Xiong, Ruoning Wang, Fei Wang, Lihua Wang, Chenxu Yan, Gaofeng Fan, Jian Cao, Quanquan Ji, Yufeng Yao, Zhiqian Guo, Ganglong Gao, Shizhen Qiu
Publikováno v:
Cell Reports, Vol 36, Iss 6, Pp 109516-(2021)
Summary Although tumor-infiltrating lymphocytes (TILs) maintain their ability to proliferate, persist, and eradicate tumors, they are frequently dysfunctional in situ. By performing both whole-genome CRISPR and metabolic inhibitor screens, we identif
Autor:
Yuetong, Wang, Fei, Wang, Lihua, Wang, Shizhen, Qiu, Yufeng, Yao, Chenxu, Yan, Xuexue, Xiong, Xuyong, Chen, Quanquan, Ji, Jian, Cao, Ganglong, Gao, Dake, Li, Liye, Zhang, Zhiqian, Guo, Ruoning, Wang, Haopeng, Wang, Gaofeng, Fan
Publikováno v:
Cell reports. 36(6)
Although tumor-infiltrating lymphocytes (TILs) maintain their ability to proliferate, persist, and eradicate tumors, they are frequently dysfunctional in situ. By performing both whole-genome CRISPR and metabolic inhibitor screens, we identify that n
Autor:
Haopeng Wang, Jian Chen, Shutan Jiang, Fei Wang, Chenqi Xu, Wen Si, Yilai Shu, Ruijun Tian, Wei Ping, Haitao Wu, Wentao Li, Shizhen Qiu, Gaofeng Fan, Wendong Chen, Jingwei Jiang
Publikováno v:
Immunity. 53(2)
Summary Clinical evidence suggests that poor persistence of chimeric antigen receptor-T cells (CAR-T) in patients limits therapeutic efficacy. Here, we designed a CAR with recyclable capability to promote in vivo persistence and to sustain antitumor