Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Shizhen, Shen"'
Autor:
Sihui Li, Shizhen Shen, Wanzhong Ge, Yixuan Cen, Songfa Zhang, Xiaodong Cheng, Xinyu Wang, Xing Xie, Weiguo Lu
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/c5944efd84e14ded8d7568a66bc64242
Autor:
Shizhen Shen, Conghui Wang, Jiaxin Gu, Feifei Song, Xiaodong Wu, Fangfang Qian, Xiaojing Chen, Lingfang Wang, Qiaohua Peng, Ziyu Xing, Lingkai Gu, Fenfen Wang, Xiaodong Cheng
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 8, Pp n/a-n/a (2024)
Abstract Epithelial ovarian cancer (EOC) is an often‐fatal malignancy marked by the development of resistance to platinum‐based chemotherapy. Thus, accurate prediction of platinum drug efficacy is crucial for strategically selecting postoperative
Externí odkaz:
https://doaj.org/article/68fd7bca827b4ca490edf549168dc9d3
Autor:
Qiaohua Peng, Yan Yu, Lele Ye, Songfa Zhang, Yang Li, Xiaoping Hua, Shizhen Shen, Dongxiao Hu, Weiguo Lu
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110376- (2024)
Summary: Ovarian cancer (OC) remains the most lethal gynecological malignant tumor. PARP inhibitors (PARPi) have significantly improved survival, particularly in patients with OC with BRCA1/2 mutations. However, the majority of patients eventually de
Externí odkaz:
https://doaj.org/article/65420ea8c4d54b788ff5a76eee3bc89f
Autor:
Chao Zhang, Qiang Guo, Lifeng Chen, Zheming Wu, Xiao-Jian Yan, Chengyang Zou, Qiuxue Zhang, Jiahong Tan, Tian Fang, Qunxian Rao, Yang Li, Shizhen Shen, Min Deng, Liewei Wang, Huanyao Gao, Jia Yu, Hu Li, Cheng Zhang, Somaira Nowsheen, Jake Kloeber, Fei Zhao, Ping Yin, Chunbo Teng, Zhongqiu Lin, Kun Song, Shuzhong Yao, Liangqing Yao, Lingying Wu, Yong Zhang, Xiaodong Cheng, Qinglei Gao, Jian Yuan, Zhenkun Lou, Jin-San Zhang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract Poly (ADP-ribose) polymerase (PARP) inhibitors are one of the most exciting classes of targeted therapy agents for cancers with homologous recombination (HR) deficiency. However, many patients without apparent HR defects also respond well to
Externí odkaz:
https://doaj.org/article/cca68174bd0f4c47bca6a90059d0f268
Autor:
Sihui Li, Shizhen Shen, Wanzhong Ge, Yixuan Cen, Songfa Zhang, Xiaodong Cheng, Xinyu Wang, Xing Xie, Weiguo Lu
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-19 (2023)
Abstract Background Epithelial ovarian cancer (EOC) is a highly prevalent disease that rapidly metastasizes and has poor prognosis. Most women are in the middle or late stages when diagnosed and have low survival rates. Recently, long non-coding RNAs
Externí odkaz:
https://doaj.org/article/99039b919a654ea1baf42424959e34a8
Autor:
Shizhen Shen, Zhangjin Shen, Conghui Wang, Xiaodong Wu, Lingfang Wang, Lele Ye, Songfa Zhang, Xiaodong Cheng
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106521- (2023)
Summary: Small extracellular vesicles (sEVs) and large extracellular vesicles (lEVs), play vital roles in intercellular communication. We optimized a method that extracts EVs from epithelial ovarian cancer (EOC) tissues for the purpose of investigati
Externí odkaz:
https://doaj.org/article/535c68e695db483e91b98f9398be8824
Autor:
Lingfang Wang, Jian Zhang, Yingfeng Su, Yasen Maimaitiyiming, Siqi Yang, Zhangjin Shen, Shitong Lin, Shizhen Shen, Guankai Zhan, Fenfen Wang, Chih-Hung Hsu, Xiaodong Cheng
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
RNA methylation has recently emerged as an important category of epigenetic modifications, which plays diverse physiopathological roles in various cancers. Recent studies have confirmed the presence of 5-methylcytosine (m5C) modification on mammalian
Externí odkaz:
https://doaj.org/article/3b06e21bd1f74338bbdb03469d8e1c79
Autor:
Xiaodong Wu, Shizhen Shen, Jiale Qin, Weidong Fei, Fengyun Fan, Jiaxin Gu, Tao Shen, Tao Zhang, Xiaodong Cheng
Publikováno v:
BJOG: An International Journal of Obstetrics & Gynaecology. 129:40-49
The aim was to assess the expression levels of SLC7A11 and GPX4 in relation to platinum resistance and prognosis in patients with epithelial ovarian cancer (EOC).A retrospective cohort study.Women's Hospital, Zhejiang University School of Medicine, H
Publikováno v:
Cellular Physiology and Biochemistry, Vol 43, Iss 4, Pp 1718-1730 (2017)
Gene mutation has been considered a research hotspot, and the rapid development of biomedicine has enabled significant advances in the evaluation of gene mutations. The advent of digital polymerase chain reaction (dPCR) elevates the detection of gene
Externí odkaz:
https://doaj.org/article/6c0a33b084bc49adae6fda9aa574a154
Autor:
Lingfang, Wang, Guankai, Zhan, Yasen, Maimaitiyiming, Yingfeng, Su, Shitong, Lin, Jinfeng, Liu, Kunhui, Su, Jiebo, Lin, Shizhen, Shen, Wentao, He, Fenfen, Wang, Jiafeng, Chen, Siqi, Sun, Yite, Xue, Jiaxin, Gu, Xiaojing, Chen, Jian, Zhang, Lu, Zhang, Qianqian, Wang, Kao-Jung, Chang, Shih-Hwa, Chiou, Mikael, Björklund, Hua, Naranmandura, Xiaodong, Cheng, Chih-Hung, Hsu
Publikováno v:
Cell reports. 41(4)
Human papillomavirus (HPV)-induced carcinogenesis critically depends on the viral early protein 7 (E7), making E7 an attractive therapeutic target. Here, we report that the E7 messenger RNA (mRNA)-containing oncotranscript complex can be selectively