Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Shiyuan Hong"'
Autor:
Ying Luo, Mengda Niu, Yanfei Liu, Miaochang Zhang, Yuanyuan Deng, Dan Mu, Junfen Xu, Shiyuan Hong
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Cervical cancer (CC) stands as a significant health threat to women globally, with high-risk human papillomaviruses as major etiologic agents. The DNA damage repair (DDR) protein topoisomerase I (TOP1) has been linked to various cancers,
Externí odkaz:
https://doaj.org/article/ce2fb40691f543fa91158c70ec526adc
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-10 (2022)
Abstract High grade serous ovarian cancer (HGSOC) is the most aggressive subtype of ovarian cancer and HGSOC patients often appear with metastasis, leading to the poor prognosis. Up to date, the extrachromosomal circular DNAs (eccDNAs) have been show
Externí odkaz:
https://doaj.org/article/3f5e8f8391214bd5b721e30643369ee2
Autor:
Junfen Xu, Yuanming Shen, Conghui Wang, Sangsang Tang, Shiyuan Hong, Weiguo Lu, Xing Xie, Xiaodong Cheng
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract The poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitors show survival benefits in ovarian cancer patients with BRCA1/2 mutation or homologous recombination (HR) deficiency, but only limited efficacy in HR-proficient ones. Another
Externí odkaz:
https://doaj.org/article/170f485243834593b335a1d6d286f515
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
High-risk human papillomaviruses (HPVs) infect epithelial cells and induce viral genome amplification upon differentiation. HPV proteins activate DNA damage repair pathways by inducing high numbers of DNA breaks in both viral and cellular DNAs.
Externí odkaz:
https://doaj.org/article/931932cf45334cafbae817683388301c
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT High-risk human papillomaviruses (HPVs) constitutively activate the ataxia telangiectasia and Rad3-related (ATR) DNA damage response pathway, and this is required for viral replication. In fibroblasts, activated ATR regulates transcription o
Externí odkaz:
https://doaj.org/article/5d0cf5180f0043dbaf1cd79c8ed96a12
Autor:
Ying Luo, Shiyuan Hong
Publikováno v:
Pathogens, Vol 9, Iss 6, p 506 (2020)
Human papillomavirus (HPV) infection leads to a variety of benign lesions and malignant tumors such as cervical cancer and head and neck squamous cell carcinoma. Several HPV vaccines have been developed that can help to prevent cervical carcinoma, bu
Externí odkaz:
https://doaj.org/article/8136f1719b544729a42f8a295902177c
Publikováno v:
mBio, Vol 6, Iss 6 (2015)
ABSTRACT The life cycle of high-risk human papillomaviruses (HPVs) is dependent upon epithelial differentiation. Following infection of basal cells, HPV genomes are stably maintained at low copy numbers, and productive replication or amplification is
Externí odkaz:
https://doaj.org/article/3c9b0d4e0994485684d093a2d582d9a0
Autor:
Shiyuan Hong, Laimonis A Laimins
Publikováno v:
PLoS Pathogens, Vol 9, Iss 4, p e1003295 (2013)
High-risk human papillomavirus (HPV) must evade innate immune surveillance to establish persistent infections and to amplify viral genomes upon differentiation. Members of the JAK-STAT family are important regulators of the innate immune response and
Externí odkaz:
https://doaj.org/article/b50b7ffae5f64602b297ca4131071edf
Autor:
Sudhir Krishna, Laimonis A. Laimins, Venkat G. Giri, Aswathy Ammothumkandy, H. Krishnamurthy, Sweta Srivastava, Jeevisha Bajaj, Annapurna Pranatharthi, Vignesh K. Gunasekharan, Shiyuan Hong, Chitra Pattabiraman
Supplementary Figure 6. CD66High cells are found at the edges of tumours and CINs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb26e817c307d501a3da55208292094
https://doi.org/10.1158/0008-5472.22404087.v1
https://doi.org/10.1158/0008-5472.22404087.v1
Autor:
Sudhir Krishna, Laimonis A. Laimins, Venkat G. Giri, Aswathy Ammothumkandy, H. Krishnamurthy, Sweta Srivastava, Jeevisha Bajaj, Annapurna Pranatharthi, Vignesh K. Gunasekharan, Shiyuan Hong, Chitra Pattabiraman
Supplementary Figure 5. Cycling and survival properties of CD66High cells from CIN-612, and CaSki spheroids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca4dda0f5d7aa0e1117f88db513a594
https://doi.org/10.1158/0008-5472.22404090
https://doi.org/10.1158/0008-5472.22404090