Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Shixue Shen"'
Autor:
James E Norton, Andrew G Lytle, Shixue Shen, Evgeni P Tzvetkov, Corin L Dorfmeier, James P McGettigan
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87098 (2014)
We have previously shown that live-attenuated rabies virus (RABV)-based vaccines infect and directly activate murine and human primary B cells in-vitro, which we propose can be exploited to help develop a single-dose RABV-based vaccine. Here we repor
Externí odkaz:
https://doaj.org/article/13155302d6564e51a863699777ae970f
Publikováno v:
AIDS Research and Human Retroviruses. 31:1126-1138
We previously showed that a matrix (M) gene-deleted rabies virus (RABV)-based vaccine (RABV-ΔM) is highly immunogenic and induces potent B cell responses in the context of RABV infection. We speculated that RABV-ΔM expressing HIV proteins would als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad8e42a0288a4fa8d95c617788f3b9d
https://doi.org/10.1089/aid.2014.0319
https://doi.org/10.1089/aid.2014.0319
Publikováno v:
Immunity, Inflammation and Disease
In vitro studies have demonstrated that the immunoreceptor tyrosine-based inhibitory motif (ITIM) of the inhibitory Fc receptor FcγRIIB is critical for mediating attenuation of signaling via immunoreceptor tyrosine-based activation motif (ITAM) cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb67f884de176eb1d8941f61d696fea
https://doi.org/10.1002/iid3.64
https://doi.org/10.1002/iid3.64
Publikováno v:
Journal of Virology. 89:2842-2848
Replication-deficient rabies virus (RABV)-based vaccines induce rapid and potent antibody responses via T cell-independent and T cell-dependent mechanisms. To further investigate early events in vaccine-induced antibody responses against RABV infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d81a2276808286edba944e249ecdaaa
https://doi.org/10.1128/jvi.03409-14
https://doi.org/10.1128/jvi.03409-14
Autor:
Nina Chi Sabins, Michelle Kinder, Sandra Santulli-Marotto, Raluca Verona, Richard Carter, Kurtis E. Bachman, Olesya Chornoguz, Vipul Bhargava, Fred Kaplan, Shixue Shen, Karen Leander
T cell expression of TIM-3 following Ag encounter has been associated with a continuum of functional states ranging from effector memory T cells to exhaustion. We have designed an in vitro culture system to specifically address the impact of anti–T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706a6510e05b74e058137c772ac46d29
https://europepmc.org/articles/PMC5713500/
https://europepmc.org/articles/PMC5713500/
Publikováno v:
Journal of Virology. 87:9217-9222
B cells secreting IgG antibodies, but not IgM, are thought to be solely responsible for vaccine-induced protection against rabies virus (RABV) infections in postexposure settings. In this report, we reinvestigated the potential for IgM to mediate pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d15787827a0707215381737271e574
https://doi.org/10.1128/jvi.00995-13
https://doi.org/10.1128/jvi.00995-13
Publikováno v:
The Journal of Immunology. 190:4923-4927
We demonstrated recently that, after accumulation of Ag-engaged B cells at the T cell zone boundaries in the spleen, these B cells migrate to the perimeter of follicles adjacent to the marginal zone. They undergo rapid proliferation at this site prio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77352f92f6a6a6b773a2a70775a346f3
https://doi.org/10.4049/jimmunol.1300350
https://doi.org/10.4049/jimmunol.1300350
Publikováno v:
Frontiers in Immunology
PD-1, TIM-3, and LAG-3 are molecules shown to have immune modulatory properties, and although initially classified as indicators of T cell hyporesponsiveness, it has become clear that they are also associated with the normal course of T cell activati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4c6c5a914cda46e2c2e9e8420b3bfc
http://europepmc.org/articles/PMC4909735
http://europepmc.org/articles/PMC4909735
Publikováno v:
Immunogenetics. 56:743-753
Toll-like receptors (TLRs) play an important role in the recognition of microbial components. Only chicken TLR2 and -4 have been reported in the literature. The objectives of this study were to identify new chicken TLRs and to evaluate evolutionary s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c0ef712968d5b63eaebc23e45342fd2
https://doi.org/10.1007/s00251-004-0740-8
https://doi.org/10.1007/s00251-004-0740-8
Autor:
Sabins, Nina C., Harman, Benjamin C., Barone, Linda R., Shixue Shen, Santulli-Marotto, Sandra
Publikováno v:
Frontiers in Immunology; 6/16/2016, p1-11, 11p