Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Shixing Zhu"'
Autor:
Mengyuan Wu, Kun Feng, Xiao Wu, Chang Liu, Shixing Zhu, Frederico S. Martins, Mingming Yu, Zhihua Lv, Meixing Yan, Sherwin K. B. Sy
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
BackgroundThe combination antimicrobial therapy consisting of amikacin, polymyxin-B, and sulbactam demonstrated in vitro synergy against multi-drug resistant Acinetobacter baumannii.ObjectivesThe objectives were to predict drug disposition and extrap
Externí odkaz:
https://doaj.org/article/a444d15486d747eea075316b80276b61
Autor:
Shixing Zhu, Jiali Yue, Xintong Wang, Jiayuan Zhang, Mingming Yu, Yuanchao Zhan, Yuanqi Zhu, Sherwin K. B. Sy, Zhihua Lv
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionThe emergence of multidrug-resistant (MDR) Acinetobacter baumannii prompts clinicians to consider treating these infections with polymyxin combination.MethodsMetabolomic analysis was applied to investigate the synergistic effects of polym
Externí odkaz:
https://doaj.org/article/d40bea0d8f99445eafdca63929107324
Autor:
Jiayuan Zhang, Shuo Diao, Yanfei Liu, Hongxiang Wang, Yuwei Liu, Shixing Zhu, Kun Feng, Xiaoqian Tang, Charles Oo, Peijuan Zhu, Zhihua Lv, Mingming Yu, Sherwin K. B. Sy, Yuanqi Zhu
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The objective of this study was to evaluate whether combinations of sulbactam, meropenem, and polymyxin-B could reduce or close the gap of mutant selection window (MSW) of individual antibiotics against Acinetobacter baumannii harboring OXA-23. MICs
Externí odkaz:
https://doaj.org/article/1ad499a4996b4ef386c794f5558c11c9
Autor:
Shixing Zhu, Chu Song, Jiayuan Zhang, Shuo Diao, Tobias M. Heinrichs, Frederico S. Martins, Zhihua Lv, Yuanqi Zhu, Mingming Yu, Sherwin K. B. Sy
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Amikacin and polymyxins as monotherapies are ineffective against multidrug-resistant Acinetobacter baumannii at the clinical dose. When polymyxins, aminoglycosides, and sulbactam are co-administered, the combinations exhibit in vitro synergistic acti
Externí odkaz:
https://doaj.org/article/b88553ff296545e7ab88a15ba49de9f4
Autor:
Shixing Zhu, Jiayuan Zhang, Chu Song, Yuwei Liu, Charles Oo, M. Tobias Heinrichs, Zhihua Lv, Yuanqi Zhu, Sherwin K. B. Sy, Pan Deng, Mingming Yu
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Empirical therapies using polymyxins combined with other antibiotics are recommended in the treatment of Acinetobacter baumannii infections. In the present study, the synergistic activities of polymyxin-B, meropenem, and sulbactam as combination ther
Externí odkaz:
https://doaj.org/article/ca87e4834fdb47e68fb88ec94c42675d
Autor:
Jiayuan Zhang, Mengyuan Wu, Shuo Diao, Shixing Zhu, Chu Song, Jiali Yue, Frederico S. Martins, Peijuan Zhu, Zhihua Lv, Yuanqi Zhu, Mingming Yu, Sherwin K. B. Sy
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 251 (2023)
This study aimed to examine specific niches and usage for the aztreonam/amoxicillin/clavulanate combination and to use population pharmacokinetic simulations of clinical dosing regimens to predict the impact of this combination on restricting mutant
Externí odkaz:
https://doaj.org/article/0e91b025d63346348f580892f4e9ab16
Autor:
Shixing Zhu, Maoyan Zhu, Andrew H. Knoll, Zongjun Yin, Fangchen Zhao, Shufen Sun, Yuangao Qu, Min Shi, Huan Liu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Macroscopic organisms are rare in the fossil record until the Ediacaran Period, beginning 635 million years ago. Here, Zhu et al. report the discovery of 1.56-billion-year-old carbonaceous compression fossils that provide evidence of the evolution of
Externí odkaz:
https://doaj.org/article/c24a1fdb24614cf9a52e5e788087010d
Autor:
Yicong Zhang, Ruili Zhang, Sherwin K.B. Sy, Zhizhong Li, Shixing Zhu, Meichen Zhou, Chu Song, Jiayuan Zhang, Zhihua Lv, Jinsong Liu, Liting Qin, Mingming Yu
Publikováno v:
Microbial Drug Resistance. 28:832-840
Autor:
Jiayuan Zhang, Chu Song, Mengyuan Wu, Jiali Yue, Shixing Zhu, Peijuan Zhu, Charles OO, Jan-Frederik Schlender, Zhihua LV, Yuanqi Zhu, Sherwin K.B. SY, Mingming YU
Publikováno v:
European Journal of Pharmaceutical Sciences. 185:106443
Autor:
Shixing Zhu, Jiayuan Zhang, Zhihua Lv, Peijuan Zhu, Charles Oo, Mingming Yu, Sherwin K. B. Sy
Publikováno v:
Clinical pharmacokinetics. 61(10)
The combination of polymyxins, meropenem, and sulbactam demonstrated efficacy against multi-drug-resistant bacillus Acinetobacter baumannii. These three antibiotics are commonly used against major blood, skin, lung, and heart muscle infections.The ob