Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Shixiang Sun"'
Autor:
Shixiang Sun, Kristina Brazhnik, Moonsook Lee, Alexander Y. Maslov, Yi Zhang, Zhenqiu Huang, Susan Klugman, Ben H. Park, Jan Vijg, Cristina Montagna
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 5 (2022)
Inherited germline mutations in the breast cancer gene 1 (BRCA1) or BRCA2 genes (herein BRCA1/2) greatly increase the risk of breast and ovarian cancer, presumably by elevating somatic mutational errors as a consequence of deficient DNA repair. Howev
Externí odkaz:
https://doaj.org/article/88f073b576eb4d2d946165cf1fe3a4e1
Publikováno v:
IEEE Access, Vol 8, Pp 66068-66073 (2020)
Identifying influential spreaders in complex networks is crucial in understanding, controlling and accelerating spreading processes for diseases, information, innovations, behaviors, and so on. We proposed a semi-local-information-based algorithm nam
Externí odkaz:
https://doaj.org/article/9fd18d3dcffc455587be2b1b9e4f90c9
Publikováno v:
Mathematics, Vol 10, Iss 6, p 970 (2022)
Community detection is a fundamental topic in network science, with a variety of applications. However, there are still fundamental questions about how to detect more realistic network community structures. To address this problem and considering the
Externí odkaz:
https://doaj.org/article/35768c454bce4925b071001b55abac78
Publikováno v:
Mathematics, Vol 9, Iss 20, p 2531 (2021)
Identifying influential edges in a complex network is a fundamental topic with a variety of applications. Considering the topological structure of networks, we propose an edge ranking algorithm DID (Dissimilarity Influence Distribution), which is bas
Externí odkaz:
https://doaj.org/article/f788935d3077410ba9679c591c19696e
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
Codon usage bias, as a combined interplay from mutation and selection, has been intensively studied in Escherichia coli. However, codon usage analysis in an E. coli pangenome remains unexplored and the relative importance of mutation and selection ac
Externí odkaz:
https://doaj.org/article/240e1f552faa439880f7cd0c2fe02a5e
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158191 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0155935.].
Externí odkaz:
https://doaj.org/article/efdbcfc1748745b5b93dacedea7ae11a
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155935 (2016)
The second law of thermodynamics states that entropy, as a measure of randomness in a system, increases over time. Although studies have investigated biological sequence randomness from different aspects, it remains unknown whether sequence randomnes
Externí odkaz:
https://doaj.org/article/be8076a06e3044b2a13c5343be640431
Publikováno v:
Journal of Control and Decision. :1-8
Autor:
Blair K Schneider, Shixiang Sun, Moonsook Lee, Wenge Li, Nicholas Skvir, Nicola Neretti, Jan Vijg, Julie Secombe
Publikováno v:
GENETICS. 224
Retrotransposons are a class of transposable elements capable of self-replication and insertion into new genomic locations. Across species, the mobilization of retrotransposons in somatic cells has been suggested to contribute to the cell and tissue
Autor:
Zhenqiu Huang, Shixiang Sun, Moonsook Lee, Alexander Y. Maslov, Miao Shi, Spencer Waldman, Ava Marsh, Taha Siddiqui, Xiao Dong, Yakov Peter, Ali Sadoughi, Chirag Shah, Kenny Ye, Simon D. Spivack, Jan Vijg
Publikováno v:
Nature Genetics. 54:492-498
Although lung cancer risk among smokers is dependent on smoking dose, it remains unknown if this increased risk reflects an increased rate of somatic mutation accumulation in normal lung cells. Here, we applied single-cell whole-genome sequencing of