Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Shiwu Dong"'
Publikováno v:
Genes and Diseases, Vol 11, Iss 4, Pp 101122- (2024)
In recent years, researchers have become focused on the relationship between lipids and bone metabolism balance. Moreover, many diseases related to lipid metabolism disorders, such as nonalcoholic fatty liver disease, atherosclerosis, obesity, and me
Externí odkaz:
https://doaj.org/article/ba3b93e63b6c4e988afe80aae2d0b947
Autor:
Hao Tang, Xiaoshan Gong, Jingjin Dai, Jun Gu, Zicai Dong, Yuan Xu, Zhaoyang Hu, Chunrong Zhao, Jiezhong Deng, Shiwu Dong
Publikováno v:
Journal of Orthopaedic Translation, Vol 44, Iss , Pp 47-59 (2024)
Background: Osteoarthritis (OA) is a chronic degenerative joint disease that primarily affects middle-aged and elderly individuals. The decline in chondrocyte function plays a crucial role in the development of OA. Inflammasome-mediated chondrocyte p
Externí odkaz:
https://doaj.org/article/d9fe5c050e8a4cccbebf005ff9755708
Autor:
Libangxi Liu, Hong Sun, Yang Zhang, Chang Liu, Yong Zhuang, Miao Liu, Xuezheng Ai, Dan Long, Bo Huang, Changqing Li, Yue Zhou, Shiwu Dong, Chencheng Feng
Publikováno v:
JOR Spine, Vol 7, Iss 1, Pp n/a-n/a (2024)
Abstract Background The N6‐methyladenosine (m6A) dynamics in the progression of intervertebral disc (IVD) aging remain largely unknown. This study aimed to explore the distribution and pattern of m6A modification in nucleus pulpous (NP) tissues of
Externí odkaz:
https://doaj.org/article/a4c9bf3b18ea4146861467e4c1166fb1
Autor:
Fanchun Zeng, Chunrong Zhao, Rujie Wang, Lingyan Ren, Hao Qiu, Zhi Zou, Haibin Ding, Zhongyi Sun, Jianmei Li, Shiwu Dong
Publikováno v:
Genes and Diseases, Vol 10, Iss 4, Pp 1626-1640 (2023)
More than 50% of prostate cancer (PCa) patients have bone metastasis with osteoblastic lesions. MiR-18a-5p is associated with the development and metastasis of PCa, but it remains unclear whether it is involved in osteoblastic lesions. We first found
Externí odkaz:
https://doaj.org/article/90276746e6aa4ac0903f66ad2543dea4
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e26226- (2024)
The anterior cruciate ligament plays an important role in maintaining the stability of the knee joint. Its injury is a common cause of articular cartilage degeneration and osteoarthritis (OA). The anterior cruciate ligament transection (ACLT) method
Externí odkaz:
https://doaj.org/article/6e75fcddba6c4a35a7606b6ca8c7d2d7
Publikováno v:
Materials Today Bio, Vol 23, Iss , Pp 100864- (2023)
Reactive oxygen burst in articular chondrocytes is a major contributor to osteoarthritis progression. Although selenium is indispensable role in the antioxidant process, the narrow therapeutic window, delicate toxicity margins, and lack of an efficie
Externí odkaz:
https://doaj.org/article/6ad61872940b489fa06555e8ce6ad20f
Publikováno v:
Animals, Vol 14, Iss 7, p 1063 (2024)
Cervidae represents a family that is not only rich in species diversity but also exhibits a wide range of karyotypes. The controversies regarding the phylogeny and classification of Cervidae still persist. The flourishing development of the genomic e
Externí odkaz:
https://doaj.org/article/a06a1abc0c804837b20412f725fe7532
Autor:
Yun Bai, Xiaoshan Gong, Rui Dong, Zhen Cao, Ce Dou, Chuan Liu, Jianmei Li, Fei Kang, Jingjin Dai, Chunrong Zhao, Zhansong Tian, Jiulin Tan, Qijie Dai, Shiwu Dong
Publikováno v:
Genes and Diseases, Vol 9, Iss 2, Pp 456-465 (2022)
Endochondral bone formation is an important route for bone repair. Although emerging evidence has revealed the functions of long non-coding RNAs (lncRNAs) in bone and cartilage development, the effect of lncRNAs in endochondral bone repair is still l
Externí odkaz:
https://doaj.org/article/54104d1e0dea44429ab1a80daadcdb80
Autor:
Ce Dou, Jianmei Li, Jian He, Fei Luo, Tao Yu, Qijie Dai, Yueqi Chen, Jianzhong Xu, Xiaochao Yang, Shiwu Dong
Publikováno v:
Bioactive Materials, Vol 6, Iss 12, Pp 4697-4706 (2021)
Antiresorptive drugs are widely used for treatment of osteoporosis and cancer bone metastasis, which function mainly through an overall inhibition of osteoclast. However, not all osteoclasts are “bone eaters”; preosteoclasts (pOCs) play anabolic
Externí odkaz:
https://doaj.org/article/222b52341c7a48ec96d5d386bcd8e05f
Publikováno v:
Bioactive Materials, Vol 6, Iss 11, Pp 3839-3850 (2021)
Osteoporosis is caused by an osteoclast activation mechanism. People suffering from osteoporosis are prone to bone defects. Increasing evidence indicates that scavenging reactive oxygen species (ROS) can inhibit receptor activator of nuclear factor
Externí odkaz:
https://doaj.org/article/f32c8d45eed94143b7f70fe553f1c5ae