Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shiwha Park"'
Publikováno v:
Proteins
Prions, misfolded proteins that aggregate, cause an array of progressively deteriorating conditions to which, currently, there are no effective treatments. The presently accepted model indicates that the soluble non-prion forms of prion-forming prote
Autor:
Minyoung Lee, Kyung Jae Jeong, Selina Vong, Shiwha Park, Chelsi Lopez, Jung-Jae Lee, Seth Edwards, Hunter Sauerland, Shujie Hou
Publikováno v:
ACS Biomaterials Science & Engineering. 5:1195-1199
Corneal melting is an uncontrolled, excessive degradation of cellular and extracellular components of the cornea. This potential cause of corneal blindness is caused by excessive expression of zinc-dependent matrix metalloproteinases (MMPs) and has n
Publikováno v:
Biomaterials Science. 7:1276-1280
A mechanically strong composite hydrogel was produced based on an interpenetrating network (IPN) between gelatin and silk fibroin. When two layers of the IPN were created, the resulting hydrogel exhibited much improved mechanical properties. This hyd
Publikováno v:
ACS Applied Bio Materials. 1:1430-1439
Injectable hydrogels can be useful tools for facilitating wound healing since they conform to the irregular shapes of wounds, serving as a temporary matrix during the healing process. However, the lack of inherent pore structures of most injectable h
Publikováno v:
ACS Biomaterials Science & Engineering. 4:3471-3477
Soft tissue integration of medical implants is important to prevent bacterial infection and implant failure. A bioadhesive that forms firm binding between the implant and the surrounding tissue and facilitates the wound-healing process will be a grea
Publikováno v:
Proteins. 86(2)
The eukaryotic eRF1 translation termination factor plays an important role in recognizing stop codons and initiating the end to translation. However, which exact complexes contain eRF1 and at what abundance is not clear. We have used analytical ultra
Autor:
Clyde L. Denis, Thomas M. Laue, Wen Xi, Shiwha Park, Chongxu Zhang, Yueh Chin Chiang, Xin Wang
Publikováno v:
Protein Science. 23:1036-1049
We have previously identified 55 nonribosomal proteins in PAB1-mRNP complexes in Saccharomyces cerevisiae using mass spectrometric analysis. Because one of the inherent limitations of mass spectrometry is that it does not inform as to the size or typ
Autor:
Darren J. Lee, Xin Wang, Chongxu Zhang, Roy Richardson, Clyde L. Denis, Thomas M. Laue, Yueh-Chin Chiang, Shiwha Park
Publikováno v:
Molecular Genetics and Genomics. 288:401-412
The poly(A)-binding protein PAB1 from the yeast Saccharomyces cerevisiae plays an important role in controlling mRNA deadenylation rates. Deletion of either its RRM1 or proline-rich domain (P domain) severely restricts deadenylation and slows mRNA de
Autor:
Chongxu, Zhang, Xin, Wang, Shiwha, Park, Yueh-chin, Chiang, Wen, Xi, Thomas M, Laue, Clyde L, Denis
Publikováno v:
Protein science : a publication of the Protein Society. 23(8)
We have previously identified 55 nonribosomal proteins in PAB1-mRNP complexes in Saccharomyces cerevisiae using mass spectrometric analysis. Because one of the inherent limitations of mass spectrometry is that it does not inform as to the size or typ