Cellular uptake of modified mRNA occurs via caveolae-mediated endocytosis, yielding high protein expression in slow-dividing cells

Autor: Claudia Del Toro Runzer, Shivesh Anand, Carlos Mota, Lorenzo Moroni, Christian Plank, Martijn van Griensven, Elizabeth R. Balmayor

Publikováno v: Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 960-979 (2023)

Nucleic acids have clear clinical potential for gene therapy. Plasmid DNA (pDNA) was the first nucleic acid to be pursued as a therapeutic molecule. Recently, mRNA came into play as it offers improved safety and affordability. In this study, we inves

Externí odkaz: https://doaj.org/article/1ddd12fb6e494d58b9485ed19a79a69e

Design and Development of Open Source Software Solution for Hyperspectral Data Simulation: Hydas

Autor: Varun Tiwari, Vinay Kumar, Kamal Pandey, Shivesh Anand, Rigved Ranade, Mohit Singh, Shefali Agrawal

Multispectral remote sensing data is available with broad spectral bands in the wavelength range of Visible-NIR-SWIR, and finds its applications in assessment of Land Use Land Cover classes (LULC). There are plenty of onboard sensors which are provid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d338dfa9c82c6cb812fd14e09bf53cfa
https://doi.org/10.21203/rs.3.rs-2316782/v1

Shaping and properties of thermoplastic scaffolds in tissue regeneration

Autor: Shivesh Anand, Andrea Roberto Calore, Ane Albillos-Sanchez, Carlos Mota, Lorenzo Moroni, Stan F.S.P. Looijmans, Jules Harings, Varun Srinivas, Lambèrt C.A. van Breemen, Katrien V. Bernaerts

Publikováno v: Journal of Materials Research, 36(19), 3914-3935. Materials Research Society

Abstract Thermoplastic semi-crystalline polymers are excellent candidates for tissue engineering scaffolds thanks to facile processing and tunable properties, employed in melt-based additive manufacturing. Control of crystallization and ultimate crys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c20c52af8cda46c4c5c6867e5529067
https://doi.org/10.1557/s43578-021-00403-2

Mimicking the Human Tympanic Membrane

Autor: T Stoppe, Lorenzo Moroni, Carlos Mota, Marcus Neudert, Timo Rademakers, Mónica Lucena, Shivesh Anand, Serena Danti

Publikováno v: Advanced Healthcare Materials, 10(11):2002082. Wiley

The human tympanic membrane (TM) captures sound waves from the environment and transforms them into mechanical motion. The successful transmission of these acoustic vibrations is attributed to the unique architecture of the TM. However, a limited kno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce6e0d028c5aaa59c89f9f4f0de0e78
https://cris.maastrichtuniversity.nl/en/publications/47fea2c3-26de-417e-b876-38fd27f3bddb

Chitin nanofibril application in tympanic membrane scaffolds to modulate inflammatory and immune response

Autor: S. Linari, Shivesh Anand, Andrea Lazzeri, Carlos Mota, Alessandra Fusco, Giovanna Donnarumma, Lorenzo Zavagna, Claudio Ricci, Stefano Berrettini, Lorenzo Moroni, Serena Danti, Bahareh Azimi, Mario Milazzo

Publikováno v: Pharmaceutics, 13(9):1440. Multidisciplinary Digital Publishing Institute (MDPI)
Pharmaceutics
Volume 13
Issue 9
Pharmaceutics, Vol 13, Iss 1440, p 1440 (2021)

Chitin nanofibrils (CNs) are an emerging bio-based nanomaterial. Due to nanometric size and high crystallinity, CNs lose the allergenic features of chitin and interestingly acquire anti-inflammatory activity. Here we investigate the possible advantag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff95fc4b991b9acd2f37c1239447782
http://hdl.handle.net/11382/541414