Zobrazeno 1 - 10
of 2 213
pro vyhledávání: '"Shivesh"'
Autor:
Shivesh Ghura, Noah R. Beratan, Xinglong Shi, Elena Alvarez-Periel, Sarah E. Bond Newton, Cagla Akay-Espinoza, Kelly L. Jordan-Sciutto
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Common single-nucleotide variants (SNVs) of eukaryotic translation initiation factor 2 alpha kinase 3 (EIF2AK3) slightly increase the risk of disorders in the periphery and the central nervous system. EIF2AK3 encodes protein kinase RNA-like
Externí odkaz:
https://doaj.org/article/cd849f67507748ea9342ece45a821b3e
Autor:
Shivesh Anand, Alessandra Fusco, Cemre Günday, Nazende Günday-Türeli, Giovanna Donnarumma, Serena Danti, Lorenzo Moroni, Carlos Mota
Publikováno v:
Bioactive Materials, Vol 38, Iss , Pp 109-123 (2024)
Approximately 740 million symptomatic patients are affected by otitis media every year. Being an inflammatory disease affecting the middle ear, it is one of the primary causes of tympanic membrane (TM) perforations, often resulting in impaired hearin
Externí odkaz:
https://doaj.org/article/37d1a0f9691b41e3a3ed4230864b67ca
Publikováno v:
Plant Nano Biology, Vol 9, Iss , Pp 100082- (2024)
The unprecedented increase in the use of nanoparticles (NPs) in domestic and industrial applications has led to their gradual accumulation in plant systems, posing a severe threat to the environment. Given that these silver NPs (AgNPs), are well know
Externí odkaz:
https://doaj.org/article/6c181c726f974a829705c6bc34f4fb18
Autor:
Ana C. Valencia-Olvera, Deebika Balu, Shreya Bellur, Thomas McNally, Yaseen Saleh, Don Pham, Shivesh Ghura, Jason York, Jan O. Johansson, Mary Jo LaDu, Leon Tai
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background Alzheimer’s disease (AD) is characterized by cognitive dysfunction and amyloid plaques composed of the amyloid-beta peptide (Aβ). APOE is the greatest genetic risk for AD with APOE4 increasing risk up to ~ 15-fold compared to A
Externí odkaz:
https://doaj.org/article/f5241d90f3904145ab4ecaa3436a668b
Autor:
Shivesh Kishore Karan, Dominic Woolf, Elias Sebastian Azzi, Cecilia Sundberg, Stephen A. Wood
Publikováno v:
GCB Bioenergy, Vol 15, Iss 12, Pp 1424-1436 (2023)
Abstract Global warming necessitates urgent action to reduce carbon dioxide (CO2) emissions and remove CO2 from the atmosphere. Biochar, a type of carbonized biomass which can be produced from crop residues (CRs), offers a promising solution for carb
Externí odkaz:
https://doaj.org/article/a992440468ab4f3cac74aa54345a2dd5
Publikováno v:
Healthline, Vol 14, Iss 3, Pp 201-209 (2023)
Introduction: Caregivers may feel stressed and burdened while caring for a stroke survivor. However, very few studies have assessed the burden among caregivers of Indian stroke patients. Objectives: The present study was done to assess the magnitude
Externí odkaz:
https://doaj.org/article/27e2f95957694e9a8b73fc2756fdb795
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Fluorescent labeling of proteins is a powerful tool for probing structure-function relationships with many biosensing applications. Structure-based rules for systematically designing fluorescent biosensors require understanding ligand-mediat
Externí odkaz:
https://doaj.org/article/4ede28d421394daea94e2600cf48249d
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0297502 (2024)
Accurately modeling large biomolecules such as DNA from first principles is fundamentally challenging due to the steep computational scaling of ab initio quantum chemistry methods. This limitation becomes even more prominent when modeling biomolecule
Externí odkaz:
https://doaj.org/article/20ad7dcfe06c4f7b9f57f2e4ea479561
Publikováno v:
Case Reports in Clinical Practice, Vol 8, Iss 4 (2024)
Pheochromocytoma is a rare catecholamine-secreting tumours of chromaffin tissues that cause a constellation of symptoms. It is closely associated with endocrine hypertension that can be masked, sustained or paroxysmal leading to hypertensive crisis,
Externí odkaz:
https://doaj.org/article/b3249626fcc94e4fae8687f6ee45efcd
Autor:
Claudia Del Toro Runzer, Shivesh Anand, Carlos Mota, Lorenzo Moroni, Christian Plank, Martijn van Griensven, Elizabeth R. Balmayor
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 960-979 (2023)
Nucleic acids have clear clinical potential for gene therapy. Plasmid DNA (pDNA) was the first nucleic acid to be pursued as a therapeutic molecule. Recently, mRNA came into play as it offers improved safety and affordability. In this study, we inves
Externí odkaz:
https://doaj.org/article/1ddd12fb6e494d58b9485ed19a79a69e