Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Shivashankar Khanapur"'
Autor:
Julian L. Goggi, Lifeng Qiu, Mei Chih Liao, Shivashankar Khanapur, Lingfan Jiang, Ramasamy Boominathan, Siddesh V. Hartimath, Peter Cheng, Fui Fong Yong, Vanessa Soh, Xiaozhou Deng, Youshan Melissa Lin, Anna Haslop, Peng Wen Tan, Xiaoxia Zeng, Jolene W. L. Lee, Zhiwei Zhang, Pragalath Sadasivam, Eng King Tan, Sajinder K. Luthra, William D. Shingleton, Steve K. W. Oh, Li Zeng, Edward G. Robins
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-14 (2020)
Abstract Background Significant developments in stem cell therapy for Parkinson’s disease (PD) have already been achieved; however, methods for reliable assessment of dopamine neuron maturation in vivo are lacking. Establishing the efficacy of new
Externí odkaz:
https://doaj.org/article/7b3a51c8d38643008824b7f536251784
Autor:
Julian L. Goggi, Siddesh V. Hartimath, Shivashankar Khanapur, Boominathan Ramasamy, Zan Feng Chin, Peter Cheng, Hui Xian Chin, You Yi Hwang, Edward G. Robins
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12892 (2022)
The low response rates associated with immune checkpoint inhibitor (ICI) use has led to a surge in research investigating adjuvant combination strategies in an attempt to enhance efficacy. Repurposing existing drugs as adjuvants accelerates the pace
Externí odkaz:
https://doaj.org/article/25b65054bfb3412988a93bfa8f8011a7
Autor:
Julian L. Goggi, Shivashankar Khanapur, Siddesh V. Hartimath, Boominathan Ramasamy, Peter Cheng, Hui-Xian Chin, Jun-Rong Tang, You-Yi Hwang, Edward G. Robins
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2343 (2022)
Often, patients fail to respond to immune checkpoint inhibitor (ICI) treatment despite favourable biomarker status. Numerous chemotherapeutic agents have been shown to promote tumour immunogenicity when used in conjunction with ICIs; however, little
Externí odkaz:
https://doaj.org/article/507bd3a96cca40bfacbd25567b24f5b3
Publikováno v:
ACS Omega, Vol 4, Iss 6, Pp 9925-9931 (2019)
Externí odkaz:
https://doaj.org/article/2dfe9e5301554cb6a594292f0e036a19
Autor:
Yi-Hao Chan, Teck-Hui Teo, Anthony Torres-Ruesta, Siddesh V. Hartimath, Rhonda Sin-Ling Chee, Shivashankar Khanapur, Fui Fong Yong, Boominathan Ramasamy, Peter Cheng, Ravisankar Rajarethinam, Edward G. Robins, Julian L. Goggi, Fok-Moon Lum, Guillaume Carissimo, Laurent Rénia, Lisa F. P. Ng
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
O'nyong-nyong virus (ONNV) is an arthritogenic alphavirus that caused two large epidemics in 1959 and 1996, affecting millions of people in Africa. More recently, sero-surveillance of healthy blood donors conducted in 2019 revealed high rates of unre
Externí odkaz:
https://doaj.org/article/934e388fe2504d76ab72f450dfa1a577
Autor:
Siddesh V. Hartimath, Boominathan Ramasamy, Tan Yun Xuan, Tang Jun Rong, Shivashankar Khanapur, Peter Cheng, You Yi Hwang, Edward G. Robins, Julian L. Goggi
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 150 (2022)
Immune checkpoint inhibitors (ICIs) block checkpoint receptors that tumours use for immune evasion, allowing immune cells to target and destroy cancer cells. Despite rapid advancements in immunotherapy, durable response rates to ICIs remains low. To
Externí odkaz:
https://doaj.org/article/9db5ad1621d3485cb8e454fb4af6b0f0
Autor:
Shivashankar Khanapur, Fui Fong Yong, Siddesh V. Hartimath, Lingfan Jiang, Boominathan Ramasamy, Peter Cheng, Pradeep Narayanaswamy, Julian L. Goggi, Edward George Robins
Publikováno v:
Molecules, Vol 26, Iss 6, p 1728 (2021)
Positron emission tomography (PET) imaging of activated T-cells with N-(4-[18F]fluorobenzoyl)-interleukin-2 ([18F]FB-IL-2) may be a promising tool for patient management to aid in the assessment of clinical responses to immune therapeutics. Unfortuna
Externí odkaz:
https://doaj.org/article/002c4c1b86854377ad1ba1a9e66d3760
Autor:
Shivashankar Khanapur, Kenneth Lye, Dipendu Mandal, Xin Jie Wee, Edward G. Robins, Rowan D. Young
Publikováno v:
Angewandte Chemie (International ed. in English). 61(49)
We report a general method for the labeling of both CF
Autor:
Julian L. Goggi, You Yi Hwang, Siddesh V. Hartimath, Beverly Jieu, Shivashankar Khanapur, Tsz Ying Yuen, Tan Yun Xuan, Laurent Rénia, Ann-Marie Chacko, Rasha Msallam, Yong Fui Fong, Peter Cheng, Boominathan Ramasamy, Tang Jun Rong, Edward G. Robins, Hui Xian Chin, Charles W. Johannes
Publikováno v:
Molecular Imaging and Biology
Purpose Chemotherapeutic adjuvants, such as oxaliplatin (OXA) and 5-fluorouracil (5-FU), that enhance the immune system, are being assessed as strategies to improve durable response rates when used in combination with immune checkpoint inhibitor (ICI
Autor:
Julian L. Goggi, Shivashankar Khanapur, Boominathan Ramasamy, Siddesh V. Hartimath, Tang Jun Rong, Peter Cheng, Yun Xuan Tan, Xin Yi Yeo, Sangyong Jung, Stephanie Shee Min Goay, Seow Theng Ong, You Yi Hwang, K. George Chandy, Edward G. Robins
Publikováno v:
Cancers; Volume 14; Issue 5; Pages: 1217
Immune checkpoint inhibitors have shown great promise, emerging as a new pillar of treatment for cancer; however, only a relatively small proportion of recipients show a durable response to treatment. Strategies that reliably differentiate durably-re