Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Shivashankar H Nagaraj"'
Autor:
Jayden Logan, Mark S Pearson, Srikanth S Manda, Young-Jun Choi, Matthew Field, Ramon M Eichenberger, Jason Mulvenna, Shivashankar H Nagaraj, Ricardo T Fujiwara, Pedro Gazzinelli-Guimaraes, Lilian Bueno, Vitor Mati, Jeffrey M Bethony, Makedonka Mitreva, Javier Sotillo, Alex Loukas
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 5, p e0008237 (2020)
The human hookworm Necator americanus infects more than 400 million people worldwide, contributing substantially to the poverty in these regions. Adult stage N. americanus live in the small intestine of the human host where they inject excretory/secr
Externí odkaz:
https://doaj.org/article/4babd1df41ee4fd4a04ad9e342026748
Autor:
Vignesh Arunachalam, Rodney Lea, Wendy Hoy, Simon Lee, Susan Mott, Judith Savige, John D. Mathews, Brendan J. McMorran, Shivashankar H. Nagaraj
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Chronic kidney disease (CKD) is highly prevalent among Indigenous Australians, especially those in remote regions. The Tiwi population has been isolated from mainland Australia for millennia and exhibits unique genetic characteris
Externí odkaz:
https://doaj.org/article/92fe68ebd55645deb7e72c2fd290eb91
Autor:
Nicholas J Hudson, Quan Gu, Shivashankar H Nagaraj, Yong-Sheng Ding, Brian P Dalrymple, Antonio Reverter
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25457 (2011)
Codon bias in the genome of an organism influences its phenome by changing the speed and efficiency of mRNA translation and hence protein abundance. We hypothesized that differences in codon bias, either between-species differences in orthologous gen
Externí odkaz:
https://doaj.org/article/18a227090fe3406283de048b5af4eb87
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 2, Iss 9, p e301 (2008)
Parasitic nematodes of humans, other animals and plants continue to impose a significant public health and economic burden worldwide, due to the diseases they cause. Promising antiparasitic drug and vaccine candidates have been discovered from excret
Externí odkaz:
https://doaj.org/article/64de89c3894d41368ebe38658e682127
Autor:
Bennett J D Datu, Robin B Gasser, Shivashankar H Nagaraj, Eng K Ong, Peter O'Donoghue, Russell McInnes, Shoba Ranganathan, Alex Loukas
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 2, Iss 1, p e130 (2008)
BACKGROUND: Third-stage larvae (L3) of the canine hookworm, Ancylostoma caninum, undergo arrested development preceding transmission to a host. Many of the mRNAs up-regulated at this stage are likely to encode proteins that facilitate the transition
Externí odkaz:
https://doaj.org/article/3f370d885406402c9651f385b0167449
Autor:
Dian Ningtyas, Russell J. Thomson, Volga Tarlac, Shivashankar H. Nagaraj, Wendy Hoy, John D. Mathews, Simon J. Foote, Elizabeth E. Gardiner, Justin R. Hamilton, Brendan J. McMorran
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The F2RL3 gene encoding protease activated receptor 4 (PAR4) contains a single nucleotide variant, rs773902, that is functional. The resulting PAR4 variants, Thr120, and Ala120, are known to differently affect platelet reactivity to thrombin. Signifi
Externí odkaz:
https://doaj.org/article/7750e3e3a71b4504a0c4bf25224be957
Autor:
Meisam Bagheri, Gadisti Aisha Mohamed, Mohammed Ashick, Mohamed Saleem, Nevena B. Ognjenovic, Hanxu Lu, Fred W. Kolling, Owen M. Wilkins, Subhadeep Das, Ian S. La Croix, Shivashankar H. Nagaraj, Kristen E. Muller, Scott A. Gerber, Todd W. Miller, Diwakar R. Pattabiraman
Publikováno v:
bioRxiv
The epithelial-mesenchymal transition (EMT) is a developmental program co-opted by tumor cells that aids the initiation of the metastatic cascade. Tumor cells that undergo EMT are relatively chemoresistant, and there are currently no therapeutic aven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2d310d76f98b7f3add17a2afd26b04
https://europepmc.org/articles/PMC10153261/
https://europepmc.org/articles/PMC10153261/
Breast cancer ranks second in the most common cancer in women worldwide with 30% of cases resulting into recurrence of the disease at distant organs post the treatment. While clinicians have utilized several clinicopathological measurements for predi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fca06f9b0003924fe2f6c431db659edf
https://doi.org/10.1101/2023.04.16.537076
https://doi.org/10.1101/2023.04.16.537076
Autor:
Brendan J. McMorran, Arvind Jaya Shankar, Simon J. Foote, Vinod Scaria, Sudhir Jadhao, Wendy E. Hoy, Hardip R. Patel, Shivashankar H. Nagaraj
Publikováno v:
The Pharmacogenomics Journal. 22:100-108
Indigenous Australians face a disproportionately severe burden of chronic disease relative to other Australians, with elevated rates of morbidity and mortality. While genomics technologies are slowly gaining momentum in personalised treatments for ma
Autor:
Sergey Knyazev, Karishma Chhugani, Varuni Sarwal, Ram Ayyala, Harman Singh, Smruthi Karthikeyan, Dhrithi Deshpande, Pelin Icer Baykal, Zoia Comarova, Angela Lu, Yuri Porozov, Tetyana I. Vasylyeva, Joel O. Wertheim, Braden T. Tierney, Charles Y. Chiu, Ren Sun, Aiping Wu, Malak S. Abedalthagafi, Victoria M. Pak, Shivashankar H. Nagaraj, Adam L. Smith, Pavel Skums, Bogdan Pasaniuc, Andrey Komissarov, Christopher E. Mason, Eric Bortz, Philippe Lemey, Fyodor Kondrashov, Niko Beerenwinkel, Tommy Tsan-Yuk Lam, Nicholas C. Wu, Alex Zelikovsky, Rob Knight, Keith A. Crandall, Serghei Mangul
Publikováno v:
ArXiv
article-version (number) 1
article-version (status) pre
Nature methods, vol 19, iss 4
article-version (number) 1
article-version (status) pre
Nature methods, vol 19, iss 4
More than any other infectious disease epidemic, the COVID-19 pandemic has been characterized by the generation of large volumes of viral genomic data at an incredible pace due to recent advances in high-throughput sequencing technologies, the rapid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7594ac9f03db7cdfd90b445fa4f44f8
https://lirias.kuleuven.be/handle/20.500.12942/694643
https://lirias.kuleuven.be/handle/20.500.12942/694643