Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Shivaram Avula"'
Autor:
Maria Otth, Katrin Scheinemann, Thankamma Ajithkumar, Kristian Aquilina, Shivaram Avula, Hoong-Wei Gan, Geert O. Janssens, Jurgen Lemiere, Giovanni Morana, Enrico Opocher, Stefan M. Pfister, Giorgio Porro, Felix Sahm, Ulrich-Wilhelm Thomale, Michelle van Egmond-Ebbeling, Hanneke M. van Santen, Barry Pizer, Stefan Rutkowski
Publikováno v:
EJC Paediatric Oncology, Vol 3, Iss , Pp 100166- (2024)
Tumours of the central nervous system (CNS) represent the most common group of solid tumours in children and adolescents up to the age of 18 years. They comprise several biological entities, subgroups, and subtypes. These subtypes and additional fact
Externí odkaz:
https://doaj.org/article/725bd3ec24ad47f99a354342f9261167
Publikováno v:
Journal of International Advanced Otology, Vol 20, Iss 1, Pp 85-88 (2024)
Externí odkaz:
https://doaj.org/article/8aff429f9d3f4f6b9bd884622461e9c4
Autor:
Cornelis M. van Tilburg, Lindsay B. Kilburn, Sébastien Perreault, Rene Schmidt, Amedeo A. Azizi, Ofelia Cruz-Martínez, Michal Zápotocký, Katrin Scheinemann, Antoinette Y. N. Schouten-van Meeteren, Astrid Sehested, Enrico Opocher, Pablo Hernáiz Driever, Shivaram Avula, David S. Ziegler, David Capper, Arend Koch, Felix Sahm, Jiaheng Qiu, Li-Pen Tsao, Samuel C. Blackman, Peter Manley, Till Milde, Ruth Witt, David T. W. Jones, Darren Hargrave, Olaf Witt
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Pediatric low-grade glioma (pLGG) is essentially a single pathway disease, with most tumors driven by genomic alterations affecting the mitogen-activated protein kinase/ERK (MAPK) pathway, predominantly KIAA1549::BRAF fusions and
Externí odkaz:
https://doaj.org/article/6042d3662e6a4c2d9fc8d41531bad22c
Autor:
Sarah Kohe, Christopher Bennett, Florence Burté, Magretta Adiamah, Heather Rose, Lara Worthington, Fatma Scerif, Lesley MacPherson, Simrandip Gill, Debbie Hicks, Edward C. Schwalbe, Stephen Crosier, Lisa Storer, Ambarasu Lourdusamy, Dipyan Mitra, Paul S. Morgan, Robert A. Dineen, Shivaram Avula, Barry Pizer, Martin Wilson, Nigel Davies, Daniel Tennant, Simon Bailey, Daniel Williamson, Theodoros N. Arvanitis, Richard G. Grundy, Steven C. Clifford, Andrew C. Peet
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104958- (2024)
Summary: Background: The malignant childhood brain tumour, medulloblastoma, is classified clinically into molecular groups which guide therapy. DNA-methylation profiling is the current classification ‘gold-standard’, typically delivered 3–4 wee
Externí odkaz:
https://doaj.org/article/7ea57b301d434c53922cf4908ce48606
Autor:
Kleoniki Roka, Katrin Scheinemann, Shivaram Avula, John H. Maduro, Ulrich W. Thomale, Astrid Sehested, A.Y.N. Schouten-Van Meeteren
Publikováno v:
EJC Paediatric Oncology, Vol 4, Iss , Pp 100169- (2024)
Pediatric low-grade gliomas are the most common brain tumours in childhood and adolescence. Despite the excellent prognosis, pediatric low-grade glioma survivors may suffer from variable long-term complications and may require repeated therapies, imp
Externí odkaz:
https://doaj.org/article/ae2892d7413847afb3e9757bac718a35
Autor:
James T. Grist, Stephanie Withey, Christopher Bennett, Heather E. L. Rose, Lesley MacPherson, Adam Oates, Stephen Powell, Jan Novak, Laurence Abernethy, Barry Pizer, Simon Bailey, Steven C. Clifford, Dipayan Mitra, Theodoros N. Arvanitis, Dorothee P. Auer, Shivaram Avula, Richard Grundy, Andrew C. Peet
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Brain tumors represent the highest cause of mortality in the pediatric oncological population. Diagnosis is commonly performed with magnetic resonance imaging. Survival biomarkers are challenging to identify due to the relatively low numbers
Externí odkaz:
https://doaj.org/article/65b300bcf0904636b1d39deb984c2b8c
Autor:
Jan Novak, Niloufar Zarinabad, Heather Rose, Theodoros Arvanitis, Lesley MacPherson, Benjamin Pinkey, Adam Oates, Patrick Hales, Richard Grundy, Dorothee Auer, Daniel Rodriguez Gutierrez, Tim Jaspan, Shivaram Avula, Laurence Abernethy, Ramneek Kaur, Darren Hargrave, Dipayan Mitra, Simon Bailey, Nigel Davies, Christopher Clark, Andrew Peet
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract To determine if apparent diffusion coefficients (ADC) can discriminate between posterior fossa brain tumours on a multicentre basis. A total of 124 paediatric patients with posterior fossa tumours (including 55 Medulloblastomas, 36 Pilocytic
Externí odkaz:
https://doaj.org/article/ceb6c559134f49fa9d1b2048f5539650
Publikováno v:
Case Reports in Pediatrics, Vol 2022 (2022)
Post-operative cerebellar mutism syndrome (CMS), also known as posterior fossa syndrome (PFS), is a well-recognized and frequent complication of surgery for posterior fossa tumours in children and young people. Its incidence varies between 8 and 31%,
Externí odkaz:
https://doaj.org/article/68e6bf7dd17840fca154e0483196ecb5
Autor:
Soumit Dasgupta, Sudhira Ratnayake, Rosa Crunkhorn, Javed Iqbal, Laura Strachan, Shivaram Avula
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Third window disorders are structural abnormalities in the bony otic capsule that establish a connection between the middle/inner ear or the inner ear/cranial cavity. Investigated extensively in adults, they have hardly been studied in children. This
Externí odkaz:
https://doaj.org/article/ba2682d29ef74cddab3608209c6d0624
Autor:
Rebecca M. Hill, Sabine L. A. Plasschaert, Beate Timmermann, Christelle Dufour, Kristian Aquilina, Shivaram Avula, Laura Donovan, Maarten Lequin, Torsten Pietsch, Ulrich Thomale, Stephan Tippelt, Pieter Wesseling, Stefan Rutkowski, Steven C. Clifford, Stefan M. Pfister, Simon Bailey, Gudrun Fleischhack
Publikováno v:
Cancers, Vol 14, Iss 1, p 126 (2021)
Relapsed medulloblastoma (rMB) accounts for a considerable, and disproportionate amount of childhood cancer deaths. Recent advances have gone someway to characterising disease biology at relapse including second malignancies that often cannot be dist
Externí odkaz:
https://doaj.org/article/f20413a582614c57b0ac6fd042529eea