Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shivapriya Chithambaram"'
Publikováno v:
Genetics
Studying phage codon adaptation is important not only for understanding the process of translation elongation, but also for reengineering phages for medical and industrial purposes. To evaluate the effect of mutation and selection on phage codon usag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b255cb17b5a82cbb951d3209c1aa56d
https://doi.org/10.1534/genetics.114.162842
https://doi.org/10.1534/genetics.114.162842
Publikováno v:
The Journal of General Virology
Rapid biosynthesis is key to the success of bacteria and viruses. Highly expressed genes in bacteria exhibit a strong codon bias corresponding to the differential availability of tRNAs. However, a large clade of lambdoid coliphages exhibits relativel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9307b45406c5c0e1447a7bd6064b7e
https://pubmed.ncbi.nlm.nih.gov/25614589
https://pubmed.ncbi.nlm.nih.gov/25614589
Publikováno v:
International journal of computational biology and drug design. 7(2-3)
The GC-rich bacterial species, Aeromonas salmonicida, is parasitised by both GC-rich phages (Aeromonas phages - phiAS7 and vB_AsaM-56) and GC-poor phages (Aeromonas phages - 25, 31, 44RR2.8t, 65, Aes508, phiAS4 and phiAS5). Both the GC-rich Aeromonas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb35aad0718a191c8c99ffbf046e5d0d
https://pubmed.ncbi.nlm.nih.gov/24878728
https://pubmed.ncbi.nlm.nih.gov/24878728
Publikováno v:
Molecular Biology and Evolution
Because phages use their host translation machinery, their codon usage should evolve toward that of highly expressed host genes. We used two indices to measure codon adaptation of phages to their host, rRSCU (the correlation in relative synonymous co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f882a5a771ea2a3c95b2981d0d126db6
https://pubmed.ncbi.nlm.nih.gov/24586046
https://pubmed.ncbi.nlm.nih.gov/24586046
Publikováno v:
BCB
Selection and mutation are the main forces that shape the codon usage patterns of viruses. Bacteriophages, just like all other viruses depend on their host's translational machinery for replication. The rate of spontaneous C→T mutations is about 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd1b2bfd8f33fce35c1f0bc527fc8810
https://doi.org/10.1145/2382936.2383035
https://doi.org/10.1145/2382936.2383035