Genetic effects of long-term captive breeding on the endangered pygmy hog

Autor: Deepanwita Purohit, Shivakumara Manu, Muthuvarmadam Subramanian Ram, Shradha Sharma, Harika Chinchilam Patnaik, Parag Jyoti Deka, Goutam Narayan, Govindhaswamy Umapathy

Publikováno v: PeerJ, Vol 9, p e12212 (2021)

Long-term captive populations often accumulate genetic changes that are detrimental to their survival in the wild. Periodic genetic evaluation of captive populations is thus necessary to identify deleterious changes and minimize their impact through

Externí odkaz: https://doaj.org/article/eb02184556344a788fb90911d189948b

Genomic potential and evolution of Dissimilatory Nitrate Reduction to Ammonium in Cyanobacteria

Autor: Manisha Ray, Shivakumara Manu, Gurdeep Rastogi, Govindhaswamy Umapathy

Cyanobacteria play an important role in primary production and nitrogen fixation. Although Cyanobacteria are well-known diazotrophic organisms, their role in other steps Nitrogen Cycle is obscure. Screening of Cyanobacterial genomes from cultured and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d1ca034016456b2fe808b4eaad63a08
https://doi.org/10.1101/2023.05.23.542008

The landscape of tolerated genetic variation in humans and primates

Autor: Hong Gao, Tobias Hamp, Jeffrey Ede, Joshua G. Schraiber, Jeremy McRae, Moriel Singer-Berk, Yanshen Yang, Anastasia Dietrich, Petko Fiziev, Lukas Kuderna, Laksshman Sundaram, Yibing Wu, Aashish Adhikari, Yair Field, Chen Chen, Serafim Batzoglou, Francois Aguet, Gabrielle Lemire, Rebecca Reimers, Daniel Balick, Mareike C. Janiak, Martin Kuhlwilm, Joseph D. Orkin, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rouselle, Felipe Ennes Silva, Lidia Agueda, Julie Blanc, Marta Gut, Dorien de Vries, Ian Goodhead, R. Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idriss S. Chuma, Julie Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Fabiano R. de Melo, Fabricio Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Farias, João Valsecchi do Amaral, Mariluce Messias, Maria N. F. da Silva, Mihir Trivedi, Rogerio Rossi, Tomas Hrbek, Nicole Andriaholinirina, Clément J. Rabarivola, Alphonse Zaramody, Clifford J. Jolly, Jane Phillips-Conroy, Gregory Wilkerson, Christian Abee, Joe H. Simmons, Eduardo Fernandez-Duque, ee Kanthaswamy, Fekadu Shiferaw, Dongdong Wu, Long Zhou, Yong Shao, Guojie Zhang, Julius D. Keyyu, Sascha Knauf, Minh D. Le, Esther Lizano, Stefan Merker, Arcadi Navarro, Thomas Batallion, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Tan, Weng Khong Lim, Andrew C. Kitchener, Dietmar Zinner, Ivo Gut, Amanda Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin M. D. Beck, Govindhaswamy Umapathy, Christian Roos, Jean P. Boubli, Monkol Lek, Shamil Sunyaev, Anne O’Donnell, Heidi Rehm, Jinbo Xu, Jeffrey Rogers, Tomas Marques-Bonet, Kyle Kai-How Farh

Publikováno v: Gao, H, Hamp, T, Ede, J, Schraiber, J G, McRae, J, Singer-Berk, M, Yang, Y, Dietrich, A S D, Fiziev, P P, Kuderna, L F K, Sundaram, L, Wu, Y, Adhikari, A, Field, Y, Chen, C, Batzoglou, S, Aguet, F, Lemire, G, Reimers, R, Balick, D, Janiak, M C, Kuhlwilm, M, Orkin, J D, Manu, S, Valenzuela, A, Bergman, J, Rousselle, M, Silva, F E, Agueda, L, Blanc, J, Gut, M, de Vries, D, Goodhead, I, Harris, R A, Raveendran, M, Jensen, A, Chuma, I S, Horvath, J E, Hvilsom, C, Juan, D, Frandsen, P, de Melo, F R, Bertuol, F, Byrne, H, Sampaio, I, Farias, I, do Amaral, J V, Messias, M, da Silva, M N F, Trivedi, M, Rossi, R, Hrbek, T, Andriaholinirina, N, Rabarivola, C J, Zaramody, A, Jolly, C J, Phillips-Conroy, J, Wilkerson, G, Abee, C, Simmons, J H, Fernandez-Duque, E, Kanthaswamy, S, Shiferaw, F, Wu, D, Zhou, L, Shao, Y, Zhang, G, Keyyu, J D, Knauf, S, Le, M D, Lizano, E, Merker, S, Navarro, A, Bataillon, T, Nadler, T, Khor, C C, Lee, J, Tan, P, Lim, W K, Kitchener, A C, Zinner, D, Gut, I, Melin, A, Guschanski, K, Schierup, M H, Beck, R M D, Umapathy, G, Roos, C, Boubli, J P, Lek, M, Sunyaev, S, O'Donnell-Luria, A, Rehm, H L, Xu, J, Rogers, J, Marques-Bonet, T & Farh, K K H 2023, ' The landscape of tolerated genetic variation in humans and primates ', Science (New York, N.Y.), vol. 380, no. 6648, abn8197 . https://doi.org/10.1126/science.abn8197
bioRxiv
Gao, H, Hamp, T, Ede, J, Schraiber, J G, McRae, J, Singer-Berk, M, Yang, Y, Dietrich, A S D, Fiziev, P P, Kuderna, L F K, Sundaram, L, Wu, Y, Adhikari, A, Field, Y, Chen, C, Batzoglou, S, Aguet, F, Lemire, G, Reimers, R, Balick, D, Janiak, M C, Kuhlwilm, M, Orkin, J D, Manu, S, Valenzuela, A, Bergman, J, Rousselle, M, Silva, F E, Agueda, L, Blanc, J, Gut, M, de Vries, D, Goodhead, I, Harris, R A, Raveendran, M, Jensen, A, Chuma, I S, Horvath, J E, Hvilsom, C, Juan, D, Frandsen, P, de Melo, F R, Bertuol, F, Byrne, H, Sampaio, I, Farias, I, do Amaral, J V, Messias, M, da Silva, M N F, Trivedi, M, Rossi, R, Hrbek, T, Andriaholinirina, N, Rabarivola, C J, Zaramody, A, Jolly, C J, Phillips-Conroy, J, Wilkerson, G, Abee, C, Simmons, J H, Fernandez-Duque, E, Kanthaswamy, S, Shiferaw, F, Wu, D, Zhou, L, Shao, Y, Zhang, G, Keyyu, J D, Knauf, S, Le, M D, Lizano, E, Merker, S, Navarro, A, Bataillon, T, Nadler, T, Khor, C C, Lee, J, Tan, P, Lim, W K, Kitchener, A C, Zinner, D, Gut, I, Melin, A, Guschanski, K, Schierup, M H, Beck, R M D, Umapathy, G, Roos, C, Boubli, J P, Lek, M, Sunyaev, S, O'Donnell-Luria, A, Rehm, H L, Xu, J, Rogers, J, Marques-Bonet, T & Farh, K K H 2023, ' The landscape of tolerated genetic variation in humans and primates ', Science (New York, N.Y.), vol. 380, no. 6648 . https://doi.org/10.1126/science.abn8197

INTRODUCTIONMillions of people have received genome and exome sequencing to date, a collective effort that has illuminated for the first time the vast catalog of small genetic differences that distinguish us as individuals within our species. However

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40093f4fd8bf53afb92b2b17f54d2dc5
https://doi.org/10.1101/2023.05.01.538953

Taxonomic diversity assessment across the tree of life from extracellular environmental DNA in aquatic ecosystems

Autor: Shivakumara Manu, Govindhaswamy Umapathy

Global biodiversity is declining at an alarming pace due to anthropogenic factors. It is imperative to monitor the health of ecosystems through biodiversity assessments. But existing biodiversity assessment approaches are not scalable to assess the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e939778e869054eb39ac79673389b0f4
https://doi.org/10.22541/au.161401815.51766652/v2

Discovery of Boar Pheromones and their Functional Role in Reproduction of Mouse Deer (Moschiola Indica)

Autor: Vinod Kumar, Shivakumara Manu, Karunakaran Caroline, Anupama Sekhar, Sajwan-Khatri Mamta, Mushkam Sandeep, Wasimuddin Wasimuddin, Balasubramanian Senthilkumaran, Govindhaswamy Umapathy

Two putative boar pheromones (Androstenone and Androstenol) were discovered in endangered mouse deer during captive breeding program. This study further examined the molecular characteristics, pheromone synthesis pathway, and the functional role of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2361f1ef20027c99aabea4713a07e3c1
https://doi.org/10.20944/preprints202210.0242.v1