Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Shiva Shajari"'
Autor:
Svenja Sydor, Natalia Smith-Cortinez, Janette Heegsma, Shiva Shajari, Ali Saeed, Klaas Nico Faber
Publikováno v:
Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1864(9), 1258-1267. ELSEVIER SCIENCE BV
Hepatic stellate cells (HSC) store vitamin A as retinyl esters and control circulating retinol levels. Upon liver injury, quiescent (q)HSC lose their vitamin A and transdifferentiate to myofibroblasts, e.g. activated (a)HSC, which promote fibrosis by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e1cafcaab3c0e6152ee7e7598758e9
https://research.rug.nl/en/publications/163b5fea-4b53-416b-9566-c29593a223a4
https://research.rug.nl/en/publications/163b5fea-4b53-416b-9566-c29593a223a4
Autor:
Shiva Shajari
Liver fibrosis is the formation of an abnormally large amount of scar tissue in response to a liver injury. Hepatic stellate cells (HSCs) play a key role in fibrogenesis in the liver. Any insult to the liver can trigger HSCs to transdifferentiate int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea6e22e3fa6234600c990d9b19de466
https://research.rug.nl/en/publications/31fbf46f-0193-4e8c-b96b-6e4710a3c9e2
https://research.rug.nl/en/publications/31fbf46f-0193-4e8c-b96b-6e4710a3c9e2
Autor:
Han Moshage, María J. Tuñón, Almudena Laliena, Klaas Nico Faber, Shiva Shajari, Janette Heegsma
Publikováno v:
Journal of Pineal Research, 59(3), 391-401
Liver fibrosis is scar tissue resulting from an uncontrolled wound-healing process in response to chronic liver injury. Liver damage generates an inflammatory reaction that activates hepatic stellate cells (HSC) that transdifferentiate from quiescent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9587b9bfa07c34d12eae52e651bf0a66
https://doi.org/10.1111/jpi.12271
https://doi.org/10.1111/jpi.12271