Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Shiva Shahrara"'
Autor:
Jaleel Jerry G. Sweis, Nabil William G. Sweis, Christian Ascoli, Benjamin Levin, Boaz Avitall, Israel Rubinstein, George Kondos, Daniel A. Culver, Marc Judson, Robert Baughman, Dawood Darbar, Wonder Drake, Shiva Shahrara, Leslie T. Cooper, Jr., Nadera J. Sweiss
Publikováno v:
Respiratory Medicine Case Reports, Vol 40, Iss , Pp 101766- (2022)
Background: Tumor necrosis factor (TNF) inhibitors have been used in the treatment of cardiac sarcoidosis, infliximab being the most commonly used. We have previously reported a case of effective treatment of cardiac sarcoidosis using adalimumab. Obj
Externí odkaz:
https://doaj.org/article/ddc5cd4b1a364b01a6f1a3b4a082c6e6
Autor:
Anja Meyer, Ryan Sienes, Brian Zanotti, Katrien van Raemdonck, Karol Palasiewicz, Daniel P. Mass, Michael V. Volin, Shiva Shahrara
Publikováno v:
Cellular & Molecular Immunology. 19:1070-1072
Autor:
Shiva Arami, Nadera J. Sweiss, Rani Rahat, Christian Ascoli, Bianca Romay, Karol Palasiewicz, Shiva Shahrara, Ryan K Zomorrodi, Chandana Tetali, Michael V. Volin, Monica Guma, Luke A. J. O'Neill, Sadiq Umar
Publikováno v:
Cellular and Molecular Life Sciences. 78:7693-7707
Recent studies have shown the significance of metabolic reprogramming in immune and stromal cell function. Yet, the metabolic reconfiguration of RA macrophages (MΦs) is incompletely understood during active disease and in crosstalk with other cell t
Autor:
Azam Ahmed, Michael V. Volin, M. Asif Amin, Karol Palasiewicz, Chandana Tetali, Ryan K Zomorrodi, Hatem A Elshabrawy, Nadera J. Sweiss, Katrien Van Raemdonck, Sadiq Umar, Bianca Romay, Shiva Shahrara
Publikováno v:
Arthritis & Rheumatology. 73:2003-2014
OBJECTIVE In rheumatoid arthritis (RA), elevated serum interleukin-34 (IL-34) levels are linked with increased disease severity. IL-34 binds to 2 receptors, macrophage colony-stimulating factor receptor (M-CSFR) and syndecan 1, which are coexpressed
Autor:
Vivienne Kahlmann, Marlies S. Wijsenbeek, Shiva Shahrara, Catharina C. Moor, Michael Manansala, Nadera J. Sweiss
Publikováno v:
Current Opinion in Pulmonary Medicine, 27(5), 463-471. Lippincott Williams & Wilkins
PURPOSE OF REVIEW: Patients with sarcoidosis may be at higher risk of coronavirus disease-19 (COVID-19) as over 90% of the patients have pulmonary involvement and many are treated with immunosuppressive agents. This review will summarize the current
Autor:
Osama Alzoubi, Anja Meyer, Tanya Pulido Gonzalez, Adel C. Burgos, Nadera Sweiss, Ryan K. Zomorrodi, Shiva Shahrara
Publikováno v:
Clinical Immunology. 251:109635
Publikováno v:
European Journal of Immunology
The molecular mechanism of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) Spike protein was characterized to identify novel therapies. The impact of tofacitinib, IL‐6R Ab, or TNFi therapy was determined on Spike protein or LPS/IFN
Autor:
Karol Palasiewicz, Imran Ahmad, Nadera J. Sweiss, Chandana Tetali, Michael V. Volin, Katrien Van Raemdonck, M. Asif Amin, Bianca Romay, Shiva Shahrara, Ryan K Zomorrodi, Sadiq Umar
Publikováno v:
Eur J Immunol
This study elucidates the mechanism of CCL25 and CCR9 in rheumatoid arthritis (RA). RA synovial fluid (SF) expresses elevated levels of CCL25 compared to OA SF and plasma from RA and normal. CCL25 was released into RA SF by fibroblasts (FLS) and macr
Autor:
Sadiq Umar, Karol Palasiewicz, Anja Meyer, Prabhakaran Kumar, Bellur S. Prabhakar, Michael V. Volin, Rani Rahat, Mina Al-Awqati, Huan J. Chang, Ryan K. Zomorrodi, Jalees Rehman, Shiva Shahrara
Publikováno v:
Cellular and Molecular Life Sciences. 79
Escalated innate immunity plays a critical role in SARS-CoV-2 pathology; however, the molecular mechanism is incompletely understood. Thus, we aim to characterize the molecular mechanism by which SARS-CoV-2 Spike protein advances human macrophage (M
Publikováno v:
Autoimmun Rev
While physiological levels of IL-7 are essential for T cell proliferation, survival and co-stimulation, its escalated concentration has been associated with autoimmune diseases such as Rheumatoid arthritis (RA). Expression of IL-7 and IL-7R in RA mon