Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Shiva Safavi"'
Autor:
Nasim Dana, Shiva Safavi, Nafiseh Nili, Badrodin Ebrahim Seyed Tabatabaei, Shaghayegh Haghjooy Javanmard
Publikováno v:
Tehran University Medical Journal, Vol 72, Iss 6, Pp 379-388 (2014)
Background: The occlusion of the artery and vein grafts are currently a major problem in coronary bypass surgery. Degradation of collagen and elastin, the most abundant extracellular matrix proteins in the vessel wall by matrix metalloproteinase (MMP
Externí odkaz:
https://doaj.org/article/a7222d00ce094cdc9f754c821d272425
Publikováno v:
ARYA Atherosclerosis, Vol 10, Iss 3, Pp 154-158 (2014)
BACKGROUND: Atherosclerosis is accepted as an inflammatory disease. Evidence suggests that inflammation evoked by injury plays a pathogenic role in all stages of atherosclerosis. This study aimed to investigate whether the high-mobility group box-1 (
Externí odkaz:
https://doaj.org/article/1bbfc534c1584dfca440d155dccbb4f1
Autor:
Joseph A. Reed, Francisco Vega, Astrid Zahn, Javier M. Di Noia, Elena M. Cortizas, Ramiro E. Verdun, Shiva Safavi
Publikováno v:
The Journal of Experimental Medicine
Verdun and colleagues find that the uracil-DNA glycosylase UNG, which promotes DNA breaks in the immunoglobulin genes during class switch recombination and is required for AID-induced chromosomal translocations, protects telomeres from AID-induced DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9963f184e6c9c334a128325ffa1fc5e8
http://europepmc.org/articles/PMC5068241
http://europepmc.org/articles/PMC5068241
Autor:
Shiva Safavi, Damien Montamat-Sicotte, Markus Müschen, Denise P. Muñoz, Alexandre Orthwein, Astrid Zahn, Javier M. Di Noia, Pablo Oppezzo, Cecilia Abreu, Ludivine C. Litzler
Publikováno v:
European Journal of Immunology. 45:2365-2376
Activation induced deaminase (AID) initiates somatic hypermutation and class switch recombination of the Ig genes in antigen-activated B cells, underpinning antibody affinity maturation and isotype switching. AID can also be pathogenic by contributin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00b45ff2a84813d36613612f7d0dca9b
https://doi.org/10.1002/eji.201545462
https://doi.org/10.1002/eji.201545462
Autor:
Shiva Safavi, David Godin, Astrid Zahn, Cheolho Cheong, Matthieu Daugan, Alain Lamarre, Javier M. Di Noia
Publikováno v:
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2013, 190 (12), pp.5949-60. ⟨10.4049/jimmunol.1202711⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2013, 190 (12), pp.5949-60. ⟨10.4049/jimmunol.1202711⟩
Activation-induced deaminase converts deoxycytidine to deoxyuridine at the Ig loci. Complementary pathways, initiated by the uracil-DNA glycosylase (UNG) or the mismatch repair factor MSH2/MSH6, must process the deoxyuridine to initiate class-switch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5bd2bee4d88e9ae28b718beebb24977
https://doi.org/10.4049/jimmunol.1202711
https://doi.org/10.4049/jimmunol.1202711
Autor:
Damien, Montamat-Sicotte, Ludivine C, Litzler, Cecilia, Abreu, Shiva, Safavi, Astrid, Zahn, Alexandre, Orthwein, Markus, Müschen, Pablo, Oppezzo, Denise P, Muñoz, Javier M, Di Noia
Publikováno v:
European Journal of Immunology
Activation induced deaminase (AID) initiates somatic hypermutation and class switch recombination of the Ig genes in antigen-activated B cells, underpinning antibody affinity maturation and isotype switching. AID can also be pathogenic by contributin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7fb135aa3a82b19d29e1cd742595f936
https://pubmed.ncbi.nlm.nih.gov/26151367
https://pubmed.ncbi.nlm.nih.gov/26151367