Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Shiva M Singh"'
Autor:
Eric J Chater-Diehl, Benjamin I Laufer, Christina A Castellani, Bonnie L Alberry, Shiva M Singh
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154836 (2016)
The molecular basis of Fetal Alcohol Spectrum Disorders (FASD) is poorly understood; however, epigenetic and gene expression changes have been implicated. We have developed a mouse model of FASD characterized by learning and memory impairment and per
Externí odkaz:
https://doaj.org/article/9bf4d2f7f60f43589069a1fcd344c8f5
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
Externí odkaz:
https://doaj.org/article/a3cd4b05e1654550a3cf5006076fa0f4
Publikováno v:
Frontiers in Pediatrics, Vol 2 (2014)
Brain development in mammals is long lasting. It begins early during embryonic growth and is finalized in early adulthood. This progression represents a delicate choreography of molecular, cellular and physiological processes initiated and directed b
Externí odkaz:
https://doaj.org/article/6a9b96829b9f4f2296815197b01397a1
Autor:
Morgan L Kleiber, Eric J Diehl, Benjamin I Laufer, Katarzyna eMantha, Aniruddho eChokroborty Hoque, Bonnie eAlberry, Shiva M Singh
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
There is abundant evidence that prenatal alcohol exposure leads to a range of behavioural and cognitive impairments, categorized under the term fetal alcohol spectrum disorders (FASDs). These disorders are pervasive in Western cultures and represent
Externí odkaz:
https://doaj.org/article/31cb84da9bf549718856b9212a684557
Autor:
Phyo W. Win, Julia Nyugen, Amanda L. Morin, Charles E. Newcomb, Shiva M. Singh, Noha Gomaa, Christina A. Castellani
Publikováno v:
BMC Research Notes, Vol 17, Iss 1, Pp 1-6 (2024)
Abstract Objective Mitochondrial dysfunction and nuclear epigenetic alterations, two hallmarks of aging, are associated with aberrant development and complex disease risk. Here, we report a method for the simultaneous assessment of mitochondrial DNA
Externí odkaz:
https://doaj.org/article/7e75765013594295828e5a9c26434cac
Autor:
Raihan K Uddin, Shiva M Singh
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69768 (2013)
A number of gene expression microarray studies have been carried out in the past, which studied aging and age-associated spatial learning impairment (ASLI) in the hippocampus in animal models, with varying results. Data from such studies were never i
Externí odkaz:
https://doaj.org/article/899f3424688149aa83f030643334a175
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62845 (2013)
BACKGROUND: Morbidity and mortality rates of low birth weight (LBW) newborns at term are higher than rates in normal birth weight (NBW) newborns. LBW newborns are at greater risk to acquire recurrent bacterial and viral infections during their first
Externí odkaz:
https://doaj.org/article/af7af01514dd4af28dd8d4204270d7f1
Autor:
Sujit Maiti, Kiran Halagur Bhoge Gowda Kumar, Christina A Castellani, Richard O'Reilly, Shiva M Singh
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17125 (2011)
Genetic individuality is the foundation of personalized medicine, yet its determinants are currently poorly understood. One issue is the difference between monozygotic twins that are assumed identical and have been extensively used in genetic studies
Externí odkaz:
https://doaj.org/article/ae74501572834ca59428607100d96cbb
Publikováno v:
Journal of Neurodevelopmental Disorders, Vol 12, Iss 1, Pp 1-16 (2020)
Abstract Background Fetal alcohol spectrum disorders (FASD) are common, seen in 1–5% of the population in the USA and Canada. Children diagnosed with FASD are not likely to remain with their biological parents, facing early maternal separation and
Externí odkaz:
https://doaj.org/article/4bf0ae8257d44c68ba53ee239588b1fa
Autor:
Aditi Thakur, Morgan L. Kleiber, Elizabeth P. Hayden, Shiva M. Singh, Yuliya Kotelnikova, Andrew R. Daoust
Publikováno v:
Child Psychiatry & Human Development. 54:672-682
Shorter telomeres mark cellular aging and are linked to chronic stress exposure as well as negative physical and psychological outcomes. However, it is unclear whether telomere length mediates associations between early stress exposure and later exte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09e6d6a9cf82ca15496389cf37a8d128
https://doi.org/10.1007/s10578-021-01279-3
https://doi.org/10.1007/s10578-021-01279-3