Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shiva Kumar, Angala"'
Autor:
Shiva Kumar Angala, Ana Carreras-Gonzalez, Emilie Huc-Claustre, Itxaso Anso, Devinder Kaur, Victoria Jones, Zuzana Palčeková, Juan M. Belardinelli, Célia de Sousa-d’Auria, Libin Shi, Nawel Slama, Christine Houssin, Annaïk Quémard, Michael McNeil, Marcelo E. Guerin, Mary Jackson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract We report on the existence of two phosphatidic acid biosynthetic pathways in mycobacteria, a classical one wherein the acylation of the sn-1 position of glycerol-3-phosphate (G3P) precedes that of sn-2 and another wherein acylations proceed
Externí odkaz:
https://doaj.org/article/e654bf1aa0a4424ea44490ddc8479d50
Autor:
Zuzana Palčeková, Andrés Obregón-Henao, Kavita De, Amanda Walz, Ha Lam, Jamie Philp, Shiva Kumar Angala, Johnathan Patterson, Camron Pearce, Sophie Zuberogoitia, Charlotte Avanzi, Jérôme Nigou, Michael McNeil, Juan F Muñoz Gutiérrez, Martine Gilleron, William H Wheat, Mercedes Gonzalez-Juarrero, Mary Jackson
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011636 (2023)
The covalent modification of bacterial (lipo)polysaccharides with discrete substituents may impact their biosynthesis, export and/or biological activity. Whether mycobacteria use a similar strategy to control the biogenesis of its cell envelope polys
Externí odkaz:
https://doaj.org/article/bb72e29f5ae744a0a16b13a47205a81c
Autor:
Heather Hodges, Kwaku Obeng, Charlotte Avanzi, Alex P. Ausmus, Shiva Kumar Angala, Karishma Kalera, Zuzana Palcekova, Benjamin M. Swarts, Mary Jackson
Publikováno v:
ACS Chemical Biology. 18:595-604
Autor:
Caroline Deshayes, Shiva Kumar Angala, Estelle Marion, Irène Brandli, Jérémie Babonneau, Laurent Preisser, Sara Eyangoh, Yves Delneste, Pierre Legras, Chantal De Chastellier, Timothy P Stinear, Mary Jackson, Laurent Marsollier
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 11, p e2502 (2013)
BACKGROUND: Mycobacterium ulcerans, a slow-growing environmental bacterium, is the etiologic agent of Buruli ulcer, a necrotic skin disease. Skin lesions are caused by mycolactone, the main virulence factor of M. ulcerans, with dermonecrotic (destruc
Externí odkaz:
https://doaj.org/article/a921efd8b48242c3bab789e0d9b9a320
Autor:
Zuzana, Palčeková, Martine, Gilleron, Shiva Kumar, Angala, Juan Manuel, Belardinelli, Michael, McNeil, Luiz E, Bermudez, Mary, Jackson
Publikováno v:
ACS Infect Dis
Lipoarabinomannan (LAM) and its biosynthetic precursors, phosphatidylinositol mannosides (PIMs) and lipomannan (LM) play important roles in the interactions of Mycobacterium tuberculosis with phagocytic cells and the modulation of the host immune res
Autor:
Crystal J, Wiersma, Juan Manuel, Belardinelli, Charlotte, Avanzi, Shiva Kumar, Angala, Isobel, Everall, Bhanupriya, Angala, Edward, Kendall, Vinicius Calado Nogueira, de Moura, Deepshikha, Verma, Jeanne, Benoit, Karen P, Brown, Victoria, Jones, Kenneth C, Malcolm, Michael, Strong, Jerry A, Nick, R Andres, Floto, Julian, Parkhill, Diane J, Ordway, Rebecca M, Davidson, Michael R, McNeil, Mary, Jackson
Publikováno v:
ACS infectious diseases. 6(8)
Understanding the physiological processes underlying the ability of
Autor:
Shiva Kumar, Angala, Wei, Li, Zuzana, Palčeková, Lu, Zou, Todd L, Lowary, Michael R, McNeil, Mary, Jackson
Publikováno v:
International Journal of Molecular Sciences
Mycobacteria produce two major lipoglycans, lipomannan (LM) and lipoarabinomannan (LAM), whose broad array of biological activities are tightly related to the fine details of their structure. However, the heterogeneity of these molecules in terms of