Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Shiva K. Angala"'
Autor:
Juan M. Belardinelli, Wei Li, Charlotte Avanzi, Shiva K. Angala, Elena Lian, Crystal J. Wiersma, Zuzana Palčeková, Kevin H. Martin, Bhanupriya Angala, Vinicius C. N. de Moura, Callan Kerns, Victoria Jones, Mercedes Gonzalez-Juarrero, Rebecca M. Davidson, Jerry A. Nick, Bradley R. Borlee, Mary Jackson
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Characterizing Mycobacterium abscessus complex (MABSC) biofilms under host-relevant conditions is essential to the design of informed therapeutic strategies targeted to this persistent, drug-tolerant, population of extracellular bacilli. Using synthe
Externí odkaz:
https://doaj.org/article/0d74ddfc88ec4837b85ab2f3e657620d
Autor:
David Albesa-Jové, Zuzana Svetlíková, Montse Tersa, Enea Sancho-Vaello, Ana Carreras-González, Pascal Bonnet, Pedro Arrasate, Ander Eguskiza, Shiva K. Angala, Javier O. Cifuente, Jana Korduláková, Mary Jackson, Katarína Mikušová, Marcelo E. Guerin
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
PatA is a membrane-associated acyltransferase that is essential for the biosynthesis of mycobacterial glycolipids. Here, Albesa-Jovéet al. describe structures of PatA from Mycobacterium smegmatisin complex with acyl donors and show that catalysis oc
Externí odkaz:
https://doaj.org/article/345eecca519f4563aed75b57f445943c
Autor:
Michal Bar-Oz, Maria Carla Martini, Maria Natalia Alonso, Michal Meir, Nicola Ivan Lore, Paolo Miotto, Camilla Riva, Shiva K Angala, Junpei Xiao, Catherine S Masiello, Maria-Anna Misiakou, Huaming Sun, Justin K Moy, Mary Jackson, Helle Krogh Johansen, Daniela Maria Cirillo, Scarlet S Shell, Daniel Barkan
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011575 (2023)
Mycobacterium abscessus causes severe disease in patients with cystic fibrosis. Little is known in M. abscessus about the roles of small regulatory RNAs (sRNA) in gene regulation. We show that the sRNA B11 controls gene expression and virulence-assoc
Externí odkaz:
https://doaj.org/article/06dacfd0952b454591cf2a3a31c618fb
Publikováno v:
ACS Chem Biol
The arabinogalactan of Corynebacterianeae is a critical heteropolysaccharide that tethers outer membrane mycolic acids to peptidoglycan thus forming the characteristic cell wall core of these prokaryotes. An essential α-(1→5)-arabinosyltransferase
Publikováno v:
Communications Chemistry, Vol 3, Iss 1, Pp 1-15 (2020)
Commun Chem
Commun Chem
Mycobacterial lipoarabinomannan (LAM) is in an essential cell envelope lipopolysaccharide anchored both to the plasma and outer membranes. To understand critical biological questions such as the biosynthesis, spatial organization of LAM within the ce
Autor:
Zuzana Palčeková, Shiva K. Angala, Mary Jackson, Michael R. McNeil, Martine Gilleron, Juan Manuel Belardinelli, Luiz E. Bermudez
Publikováno v:
ACS Infectious Diseases. 6:2235-2248
Lipoarabinomannan (LAM) and its biosynthetic precursors, phosphatidylinositol mannosides (PIMs) and lipomannan (LM) play important roles in the interactions of Mycobacterium tuberculosis with phago...
Autor:
Juan Manuel Belardinelli, Michael R. McNeil, Bhanupriya Angala, Michael J. Strong, Karen Brown, Julian Parkhill, Jeanne Benoit, Victoria Jones, Deepshikha Verma, Shiva K. Angala, Jerry A. Nick, Kenneth C. Malcolm, Edward Kendall, Charlotte Avanzi, Isobel Everall, Mary Jackson, R. Andres Floto, Crystal J Wiersma, Rebecca M. Davidson, Diane J. Ordway, Vinicius Calado Nogueira de Moura
Publikováno v:
ACS Infectious Diseases
Understanding the physiological processes underlying the ability of Mycobacterium abscessus to become a chronic pathogen of the cystic fibrosis (CF) lung is important to the development of prophylactic and therapeutic strategies to better control and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa1f8805dfbe18f2e6b2afd8cf0d7af
https://zenodo.org/record/4784612
https://zenodo.org/record/4784612
Autor:
Zuzana Palčeková, Haig A. Eskandarian, Richard Brunton, Victoria Jones, Michael R. McNeil, Jérôme Nigou, Maju Joe, Mary Jackson, Shiva K. Angala, Todd L. Lowary, Juan Manuel Belardinelli, Christopher D. Rithner, Martine Gilleron
Publikováno v:
J Biol Chem
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2019, 294 (26), pp.10325-10335. ⟨10.1074/jbc.RA119.008585⟩
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2019, 294 (26), pp.10325-10335. ⟨10.1074/jbc.RA119.008585⟩
Similar to other prokaryotes, mycobacteria decorate their major cell envelope glycans with minor covalent substituents whose biological significance remains largely unknown. We report on the discovery of a mycobacterial enzyme, named here SucT, that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf471f40a4254d4c97005d805ef0eb3b
https://europepmc.org/articles/PMC6664188/
https://europepmc.org/articles/PMC6664188/
Autor:
Mary Jackson, Shiva K. Angala
Publikováno v:
Methods in Molecular Biology ISBN: 9781493991532
D-Arabinofuranose is a major glycosyl constituent of mycobacteria found in two essential cell envelope heteropolysaccharides, arabinogalactan and lipoarabinomannan. Seven different arabinosyltransferases at least are required to synthesize the arabin
Autor:
Ana Carreras-González, Zuzana Svetlíková, Marcelo E. Guerin, Pedro Arrasate, Shiva K. Angala, Jana Korduláková, Javier O. Cifuente, Enea Sancho-Vaello, Katarína Mikušová, Pascal Bonnet, Ander Eguskiza, Montse Tersa, David Albesa-Jové, Mary Jackson
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Addi. Archivo Digital para la Docencia y la Investigación
instname
Nature Communications
Addi. Archivo Digital para la Docencia y la Investigación
instname
Nature Communications
The biosynthesis of phospholipids and glycolipids are critical pathways for virtually all cell membranes. PatA is an essential membrane associated acyltransferase involved in the biosynthesis of mycobacterial phosphatidyl-myo-inositol mannosides (PIM