Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Shiuh-Ming Luoh"'
Publikováno v:
Nucleic Acids Research
GeneHub-GEPIS is a web application that performs digital expression analysis in human and mouse tissues based on an integrated gene database. Using aggregated expressed sequence tag (EST) library information and EST counts, the application calculates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa9fffc45c4f41f27ee3ae0efca4d33
https://doi.org/10.1093/nar/gkm381
https://doi.org/10.1093/nar/gkm381
Autor:
Neil Gesundheit, Lena M. S. Carlsson, Robin Covello, Kenneth M. Attie, James A. Wells, Shiuh-Ming Luoh, Audrey Goddard, Amy Chen Rundle, Tim Clackson
Publikováno v:
New England Journal of Medicine. 333:1093-1098
Background Short stature in children who are not deficient in growth hormone (GH) is probably caused by a variety of defects. Some children with idiopathic short stature have low serum concentrations of GH-binding protein, which is derived from the G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01d8d6e8d6ea82dbe69133afabee73a3
https://doi.org/10.1056/nejm199510263331701
https://doi.org/10.1056/nejm199510263331701
Autor:
Marcia Belvin, Jeanne Cheung, Rafael Cubas, Marina Moskalenko, Stephen E. Gould, Erin McNamara, Shiuh-Ming Luoh, Jeong Kim
Publikováno v:
Cancer Immunology Research. 4:A114-A114
Immunotherapy with checkpoint inhibitors has proven to be highly effective, with durable responses in a subset of patients. In an effort to broaden the number of responding individuals, overcome resistance to single-agent therapy and extend the durat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff6b702c6ce581fc5cf44b30f54233f3
https://doi.org/10.1158/2326-6066.imm2016-a114
https://doi.org/10.1158/2326-6066.imm2016-a114
Autor:
Erin Williams, Shiuh-Ming Luoh, Mark Merchant, Christine Orr, Jeanne Cheung, Ira Mellman, Marcia Belvin, Jeong Kim, Emily Chan, Peter J.R. Ebert
Publikováno v:
Cancer Research. 76:4905-4905
Immunotherapeutic agents have shown great promise in the clinic in recent years and this has led to their approval as single agents or as immune doublet combinations in melanoma and lung cancer. In order to increase the extent of benefit from these a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f402bd80b39807a982ebe6c3386a2c7a
https://doi.org/10.1158/1538-7445.am2016-4905
https://doi.org/10.1158/1538-7445.am2016-4905
Publikováno v:
Cancer Research. 76:4898-4898
Immunotherapeutic agents have shown dramatic success in oncology in recent years and several have been approved in melanoma and lung cancer. One strategy for extending the benefit of immunotherapy is to evaluate these agents in combination with stand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0baf987bad8e795c30dc01ba12e07701
https://doi.org/10.1158/1538-7445.am2016-4898
https://doi.org/10.1158/1538-7445.am2016-4898
Autor:
K L King, J Rullamas, Diane Pennica, D S Knutzon, Shiuh-Ming Luoh, E Luis, Kenneth R. Chien, K J Shaw, R Yen, W C Darbonne
Publikováno v:
Proceedings of the National Academy of Sciences. 92:1142-1146
Heart failure continues to be a leading cause of mortality worldwide. A hallmark of this disease is dilated cardiac hypertrophy, which is accompanied by a reactivation of genes expressed in fetal heart development. Reasoning that fetal or embryonic g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9703a9cfb92c2b93c336d5cf32bf4114
https://doi.org/10.1073/pnas.92.4.1142
https://doi.org/10.1073/pnas.92.4.1142
Autor:
Jacob R. Haling, Kyung Song, Daniel Anderson, Shiva Malek, Marcia Belvin, Jocelyn Chan, Joanne Frances Mary Hewitt, Christian Wiesmann, Robert Heald, Klaus P. Hoeflich, Lori Friedman, Steve Price, Mark Merchant, Mary J. C. Ludlam, Georgia Hatzivassiliou, Mark Zak, Huifen Chen, Mark Ultsch, Ariana Peck, Shiuh-Ming Luoh, Christine Orr
Publikováno v:
Nature. 501(7466)
KRAS and BRAF activating mutations drive tumorigenesis through constitutive activation of the MAPK pathway. As these tumours represent an area of high unmet medical need, multiple allosteric MEK inhibitors, which inhibit MAPK signalling in both genot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b5e4a47bc834c601f649fd6d2ae5eb6
https://pubmed.ncbi.nlm.nih.gov/23934108
https://pubmed.ncbi.nlm.nih.gov/23934108
Autor:
Austin L. Gurney, Christa Grey, Donna M. Stone, Frederic J. de Sauvage, Maximilien Murone, Shiuh-Ming Luoh, Arnon Rosenthal, Wenlu Li, Mark Armanini
Publikováno v:
Nature Cell Biology. 2:310-312
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3c3f08c6dacd44f659debd45fddd19
https://doi.org/10.1038/35010610
https://doi.org/10.1038/35010610
Autor:
Jeannette M. Bonifas, Ervin H. Epstein, Audrey Goddard, Chaohui Zhang, Jingwu Xie, Mary Hynes, Shiuh Ming Luoh, Frederic J. de Sauvage, Ching-Wan Lam, Qimin Gu, Arnon Rosenthal, Maximilien Murone, Anne M. Ryan
Publikováno v:
Nature. 391:90-92
Basal-cell carcinomas (BCCs) are the commonest human cancer. Insight into their genesis came from identification of mutations in the PATCHED gene (PTCH) in patients with the basal-cell nevus syndrome, a hereditary disease characterized by multiple BC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948a20b44322b3bf93c9eb1977691d2d
https://doi.org/10.1038/34201
https://doi.org/10.1038/34201
Autor:
Mark Merchant, Julio Ramirez, Marie Evangelista, Frederic J. de Sauvage, Gretchen Frantz, Ellen Filvaroff, Leanne McFarland, Sreedevi Chalasani, Dorothy French, Richard A.D. Carano, Annie Ogasawara, Shiuh-Ming Luoh, Marjie van Hoy
The Drosophila Fused (Fu) kinase is an integral component of the Hedgehog (Hh) pathway that helps promote Hh-dependent gene transcription. Vertebrate homologues of Fu function in the Hh pathway in vitro, suggesting that Fu is evolutionarily conserved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931a57a818a052983f9de7a6e5a87a41
https://europepmc.org/articles/PMC1190232/
https://europepmc.org/articles/PMC1190232/
