Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Shiu-Wen Huang"'
Autor:
Shiu-Wen Huang, Ming Jen Hsu, Hsiu-Chen Chen, Rita Meleddu, Simona Distinto, Elias Maccioni, Filippo Cottiglia
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractThe phytochemical investigation of the methanol extract of the seeds of Magydaris pastinacea afforded two undescribed benzofuran glycosides, furomagydarins A-B (1, 2), together with three known coumarins. The structures of the new isolates we
Externí odkaz:
https://doaj.org/article/4ede0bc6e01e44d398ce55962401b995
Autor:
Ming-Jen Hsu, Han-Kun Chen, Cheng-Yu Chen, Jin-Cherng Lien, Jing-Yan Gao, Yu-Han Huang, Justin Bo-Kai Hsu, Gilbert Aaron Lee, Shiu-Wen Huang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Background and PurposeBenzimidazoles have attracted much attention over the last few decades due to their broad-spectrum pharmacological properties. Increasing evidence is showing the potential use of benzimidazoles as anti-angiogenic agents, althoug
Externí odkaz:
https://doaj.org/article/80ef20ba44e64b409623a876c5a41dfa
Publikováno v:
Cells, Vol 11, Iss 13, p 2114 (2022)
Natural naphthoquinones and their derivatives exhibit a broad spectrum of pharmacological activities and have thus attracted much attention in modern drug discovery. However, it remains unclear whether naphthoquinones are potential drug candidates fo
Externí odkaz:
https://doaj.org/article/4eefbfee7821493bb7b556b2e46533dd
Autor:
Shiu-Wen Huang, Hung-Yu Yang, Wei-Jan Huang, Wei-Chuan Chen, Meng-Chieh Yu, Shih-Wei Wang, Ya-Fen Hsu, Ming-Jen Hsu
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Background and purpose: Angiogenesis and lymphangiogenesis are major routes for metastatic spread of tumor cells. It thus represent the rational targets for therapeutic intervention of cancer. Recently, we showed that a novel aliphatic hydroxamate-ba
Externí odkaz:
https://doaj.org/article/09e8f70de02541a3988273f8a28d18ef
Autor:
Chia-Sheng Yen, Cheuk-Sing Choy, Wei-Jan Huang, Shiu-Wen Huang, Pin-Ye Lai, Meng-Chieh Yu, Ching Shiue, Ya-Fen Hsu, Ming-Jen Hsu
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Growing evidence shows that hydroxamate-based compounds exhibit broad-spectrum pharmacological properties including anti-tumor activity. However, the precise mechanisms underlying hydroxamate derivative-induced cancer cell death remain incomplete und
Externí odkaz:
https://doaj.org/article/7e03a2bd0dfb462081c06a5d564c668c
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158839 (2016)
Elevated serum interleukin-6 (IL-6) levels correlates with tumor grade and poor prognosis in cancer patients. IL-6 has been shown to promote tumor lymphangiogenesis through vascular endothelial growth factor-C (VEGF-C) induction in tumor cells. We re
Externí odkaz:
https://doaj.org/article/7b0285ebe8004438823d20aa4db6e9a6
Autor:
Yu-Fan Chuang, Mei-Chieh Chen, Shiu-Wen Huang, Ya-Fen Hsu, George Ou, Yu-Jou Tsai, Ming-Jen Hsu
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0137177 (2015)
The lymphatic endothelium plays an important role in the maintenance of tissue fluid homeostasis. It also participates in the pathogenesis of several inflammatory diseases. However, little is known about the underlying mechanisms by which lymphatic e
Externí odkaz:
https://doaj.org/article/61253afc0a7c4083867a338c21087fb0
Autor:
Yu-Hsin Chien, Chia-Yuan Lin, Shih-Yuan Hsu, Yue-Hwa Chen, Hung-Tsung Wu, Shiu-Wen Huang, Yang-Ching Chen
Publikováno v:
Nutrients; Volume 15; Issue 10; Pages: 2319
The effects of consuming specific types of nonnutritive sweeteners (NNSs) on adiposity changes in children have remained inconsistent. In this study, we aimed to investigate the effects of the intake of different kinds of NNSs on long-term adiposity
Publikováno v:
The Journal of Allergy and Clinical Immunology: In Practice.
Autor:
Yu-Han Huang, Han-Kun Chen, Ya-Fen Hsu, Hsiu-Chen Chen, Chin-Hui Chuang, Shiu-Wen Huang, Ming-Jen Hsu
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6650
Colorectal cancer is one of the most prevalent and lethal malignancies, affecting approximately 900,000 individuals each year worldwide. Patients with colorectal cancer are found with elevated serum interleukin-6 (IL-6), which is associated with adva