Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shiu Yeung Lam"'
Autor:
Zeliha Yalçin, Shiu Yeung Lam, Marieke H. Peuscher, Jaco van der Torre, Sha Zhu, Prasanna V. Iyengar, Daniel Salas-Lloret, Inge de Krijger, Nathalie Moatti, Ruben van der Lugt, Mattia Falcone, Aurora Cerutti, Onno B. Bleijerveld, Liesbeth Hoekman, Román González-Prieto, Jacqueline J. L. Jacobs
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Maintenance of genome integrity requires tight control of DNA damage response (DDR) signalling and repair, with phosphorylation and ubiquitination representing key elements. How these events are coordinated to achieve productive DNA repair r
Externí odkaz:
https://doaj.org/article/5904fb9cf15e4ea0bcf5f618e256368f
Autor:
Lvwen Ning, Josephine Mun-Yee Ko, Valen Zhuoyou Yu, Hoi Yan Ng, Candy King-Chi Chan, Lihua Tao, Shiu-Yeung Lam, Merrin Man-Long Leong, Roger Kai-Cheong Ngan, Dora Lai-Wan Kwong, Anne Wing-Mui Lee, Wai-Tong Ng, Ashley Cheng, Stewart Tung, Victor Ho-Fun Lee, Ka-On Lam, Chung-Kong Kwan, Wing-Sum Li, Stephen Yau, Jin-Xin Bei, Maria Li Lung
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-13 (2020)
Here the authors report a major histocompatibility complex (MHC) association analysis for nasopharyngeal carcinoma in Chinese individuals from Hong Kong, finding 8 independent associated loci associated with lower risk for developing nasopharyngeal c
Externí odkaz:
https://doaj.org/article/f82cb968f4d947bb91dd4a6ed21c1e75
Autor:
Annie Wai Yeeng Chai, Carissa Wing Yan Wong, Maria Li Lung, Lisa Chan Lei, Shiu Yeung Lam, Lvwen Ning, Josephine Mun Yee Ko, Sheyne Sta Ana Choi
Publikováno v:
Cancers
Volume 13
Issue 18
Cancers, Vol 13, Iss 4715, p 4715 (2021)
Volume 13
Issue 18
Cancers, Vol 13, Iss 4715, p 4715 (2021)
Simple Summary Two deleterious RAD50 loss-of-function germline mutations were identified from the blood DNA of a cohort of 3289 Henan individuals by next-generation sequencing. These rare loss-of-function RAD50 variants were associated with a substan
Publikováno v:
Proceedings of The 1st International Electronic Conference on Cancers: Exploiting Cancer Vulnerability by Targeting the DNA Damage Response.
Autor:
Hoi Yan Ng, Stephen S.-T. Yau, Dora L.W. Kwong, Chung-Kong Kwan, Wai Tong Ng, Wing-Sum Li, Stewart Tung, Lvwen Ning, Merrin Man-Long Leong, Ashley Cheng, Ka-On Lam, Shiu-Yeung Lam, Roger Kai Cheong Ngan, Lihua Tao, Anne Wing-Mui Lee, Jin-Xin Bei, Valen Zhuoyou Yu, Maria Li Lung, Victor Ho-Fun Lee, Candy King-Chi Chan, Josephine Mun Yee Ko
Publikováno v:
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-13 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-13 (2020)
Despite pronounced associations of major histocompatibility complex (MHC) regions with nasopharyngeal carcinoma (NPC), causal variants underlying NPC pathogenesis remain elusive. Our large-scale comprehensive MHC region deep sequencing study of 5689
Publikováno v:
Cancer Research. 78:327-327
Esophageal squamous cell carcinoma (ESCC), a histological subtype of esophageal cancer, is a highly prevalent malignancy in Southeast Asia with poor prognosis and high mortality rate. From previous Next-Generation Sequencing (NGS) studies that sample